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Celgene clinically ahead, but ...

To say whether U.S. regulators will require heart monitoring after the first dose of Arena Pharmaceuticals Inc.'s etrasimod for ulcerative colitis (UC) would be "prognosticating a bit in terms of what the FDA is going to choose to do," said Chief Medical Officer (CMO) Preston Klassen, who refused such guesswork.

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GWAS in Chinese population implicates immune system in Alzheimer's disease

A study has identified common genetic variants in the Chinese population contributing to the risk of developing Alzheimer's disease (AD) that possibly exert functional effects through the immune system, which could have important implications for AD management.

The search continues for promising biomarkers and effective disease-modifying therapies for AD. The current drug development approaches mainly target the disease's hallmark pathology of amyloid-beta (Abeta) protein accumulation in the brain leading to Abeta plaque deposition.



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