The complement system is designed to kill pathogens through a signal cascade that results in cell lysis, removal of the pathogens through phagocytosis, and alerting other immune system cells to help with infections. Signals come from three different pathways – classical, lectin and alternative – culminating at the C3 protein of the cascade. Read More
It will come as no surprise that the Street's passion for biotech initial public offerings (IPO) has waned lately in the wake of the sector's overall poor market performance during the past few weeks. Read More
When cancers become resistant to the drugs used to treat them, it has become possible – at least in principle – to understand the cause of that resistance through sequencing, and if a drug exists that is effective against cells with the mutation, to change a patient's treatment accordingly. But a better strategy might be to prevent resistance from developing at all. Read More