The safety profile of CT-P13, a biosimilar candidate to Rituxan, also was comparable to the approved drug...Galapagos said the short-term efficacy and favorable safety profile supported the potential of JAK1 inhibition for RA treatment and confirmed results of its previous proof-of-concept study
Ablynx NV, of Ghent, Belgium, will make an oral and poster presentation for arthritis candidate, ALX-0061, at the Annual European Congress of Rheumatology in Madrid, Spain, showing a strong efficacy and safety profile for the drug in a Phase II study
DiaPep277 was well tolerated with a good safety profile, similar to that observed in DIA-AID 1 , and no drug-related serious adverse events were reported
No safety concerns relating to any of the aforementioned products have been identified in any preclinical and clinical data generated to date and there is no reason to believe that the favorable safety profile of the products will be affected
Taken together, the three studies demonstrated that AE37 is meeting or exceeding all expectations for generating a specific, robust and long-lived immune response while maintaining a favorable safety profile, the company said
AstraZeneca plc, of London, said results from two pivotal Phase III studies of naloxegol showed that the 25-mg dose met its primary and secondary endpoints for efficacy and showed a safety profile consistent with previous studies
Data from the Phase I study established that LPCN 1111 exhibited a strong safety profile and pharmacokinetics, which should allow for once-a-day dosing of the next-generation oral testosterone replacement product, Lipocine said
Galapagos NV, of Mechelen, Belgium, said GLPG0974, an inhibitor of FFA2 (free fatty acid receptor 2, formerly GPR43) in development for chronic neutrophil-driven inflammatory conditions such as inflammatory bowel disease, showed a clean safety profile and a strong biomarker signal in the second Phase I trial
The trial will be launched at Mexico's Hospital Angeles with the Regenerative Medicine Institute, using an initial cohort of five patients to help establish a safety profile and demonstrate preliminary efficacy
The results demonstrate that Pradaxa 150 mg twice daily is an effective option with a favorable safety profile for the extended prevention of recurrence of venous blood clots (known as venous thromboembolism) after a first event
At all doses tested, ALX-0061 was well tolerated and the safety profile compared favorably to data reported for other biological DMARDs...A third poster reviews the safety profile of poxviral vaccines from eight separate trials of PROSTVAC and the immunotherapy CV-301
The safety profile of the program remains consistent with what has been seen in the post-menopausal osteoporosis (PMO) program and is not a factor in the decision to not pursue acceleration of fracture healing
The primary objective is to establish the safety profile of VGX-100, while secondary objectives include determination of anti-tumor activity, biomarker levels and pharmacokinetics...The vaccine was well tolerated, and its safety profile was comparable to other pediatric vaccines
Spectrum Pharmaceuticals Inc., of Henderson, Nev., said data from the BELIEF trial showed belinostat had an acceptable safety profile in patients with relapsed/refractory peripheral T-cell lymphoma, including those who received a previous allogeneic or autologous stem cell transplant
The preliminary analysis showed that BI-505, a human antibody, has a good safety profile and in cohorts where extended therapy was available, 24 percent of the patients had stable disease for at least two months
Preclinical data have shown that Benepenem has potent in vitro and in vivo activities, a good safety profile and a long half-life compatible with once-daily dosing
The study showed a good safety profile, with no drug-related serious adverse events to date