Fifty percent (eight patients) met the primary endpoint, defined as a reduction in the Mayo score between baseline and completion of treatment, while the remaining eight patients demonstrated a stable clinical condition or minor improvement

Primary endpoints include sustained virologic response at four weeks...The primary endpoints will be cell body distribution and bone markers

Both combinations of aclidinium/formoterol showed statistically significant improvements in the co-primary endpoints of change from baseline in morning predose through FEV1 vs

Both studies met the primary endpoint of significant pain relief compared to placebo

The primary endpoint is change in quality of life and physical functioning, including the six-minute walk test, body weight, Kansas City Cardiomyopahty Questionnaire, NT-pro BNP and time to first heart failure hospitalization, decongestion therapy or death

The primary endpoints are safety and tolerability, with secondary endpoints including the pharmacokinetic profile of the drug and an efficacy evaluation as assessed by various parameters, such as response rate as measured by bone marrow biopsy

The primary endpoint of the study is the induction of clinical remission at week 12

As previously reported, Study 202 met its primary endpoint of increased novel dystrophin as assessed by muscle biopsy at week 48

The primary endpoint will be the average number of events per patient, over a 12-month period...The primary endpoint of that cohort was to obtain a 40 percent progression-free survival rate at four months of treatment...The primary endpoint is 90-day overall survival, and the safety and tolerability of the two treatment groups will also be compared

The primary endpoint is the effect of GI-6207 on changes in calcitonin levels after six months of treatment vs

The primary endpoint will be a Systemic Lupus Erythematosus Response Index-8. (See BioWorld Today, Jan. 28, 2013...The primary endpoint – specified as nine or more patients in both stages, combined, achieving a partial response or better – was met after 21 evaluable patients were treated

The study enrolled 127 patients and tested the drug against placebo nasal spray, with co-primary endpoints defined as the mean minutes spent binge eating and the mean scores on the standard Binge Eating Scale...The study is enrolling 280 women with heavy uterine bleeding associated with uterine fibroids and will test elagolix against placebo, with an assessment of the change in menstrual blood loss using the alkaline hematin method comparing baseline to month six as the primary endpoint

The primary endpoint was the change in degrees from baseline to the day 92 follow-up in active forward flexion in the affected shoulder compared to the exercise-only cohort, with both the 0.58 mg (1 mL) and 0.58 mg (2 mL) dosing arms showing positive, statistically significant improvement...Tedizolid met its primary endpoint of non-inferiority (10% NI margin) to linezolid as measured by a 20 percent or greater reduction in lesion area at 48 to 72 hours after the first infusion

Ohr Pharmaceutical Inc., of New York, said a Phase II trial to evaluate the effects of OHR/AVR118 in advanced cancer patients with cachexia did not meet the primary endpoint of weight gain, but the 18 patients who completed the treatment protocol achieved stable body weight, body fat and muscle mass with a significant increase in appetite (p = 0.001

Teva Pharmaceutical Industries Ltd., of Jerusalem, and H. Lundbeck A/S, of Copenhagen, Denmark, said the ANDANTE (Add oN to Dopamine AgoNists in the TrEatment of Parkinson's disease), testing Azilect (rasagiline tablets) as an add-on treatment to dopamine agonists compared to placebo met its primary endpoint

The drug met the primary endpoint of reducing annualized relapse rate by 36 percent vs...The primary endpoint is safety, while the secondary endpoint is gluteal muscle function at six months, with the ability to perform biopsies of the involved muscle

The primary endpoint was the IPSS score, with secondary measures including the International Index of Erectile Function-Erectile Function Domain and the Treatment Satisfaction Scale-Benign Prostatic Hyperplasia questionnaire

The study showed that Uceris 9 mg gave a statistically significant benefit over placebo for the primary endpoint of clinical and endoscopic remission at week eight

The trial has as its primary endpoint changes in scar vascularity, height and thickness, pliability and pigmentation of scars, compared to a dimethicone comparator