ViroPharma Inc., of Exton, Pa., and Halozyme Therapeutics Inc., of San Diego, said the FDA provided guidance enabling ViroPharma to resume clinical trials testing the subcutaneous administration of hereditary angioedema drug Cinryze (C1 esterase inhibitor [human]) in combination with Halozyme's recombinant human hyaluronidase (rHuPH20

Imprimis Pharmaceuticals Inc., of Solana Beach, Calif., said it started a clinical trial testing Impracor, a topical cream designed to deliver ketoprofen

Aeras, of Rockville, Md., and the Infectious Disease Research Institute (IDRI) said they started a clinical trial of IDRI's tuberculosis vaccine candidate, ID93 + GLA-SE...Pacific Therapeutics Ltd., of Vancouver, British Columbia, said it completed enrollment and initial dosing in its first clinical trial testing PTL-202 in healthy volunteers

If approved, the product, indicated for the treatment of autoimmune and inflammatory diseases, will enter clinical trials

Immatics biotechnologies GmbH, of Tübingen, Germany, published data from two clinical trials of IMA901, a cancer vaccine candidate, showing that patients experience longer survival times when their immune system responds to more than one of the peptides in the vaccine

Infectex, of Moscow, said it received approval from the Russian Ministry of Health to begin a pivotal clinical trial for antibiotic SQ109 in multidrug-resistant tuberculosis (MDR-TB) patients at TB centers in three major Russian cities (Moscow, Saint Petersburg and Ekaterinburg

BHR Pharma LLC, of Phoenix, said it reached its SyNAPSe clinical trial enrollment midpoint of 590 patients...ICT-121 is the second dendritic-cell-based vaccine to enter clinical trials

Catalyst Pharmaceutical Partners Inc., of Coral Gables, Fla., said Phase IIa ocular safety results published in the American Journal of Ophthalmology showed that CPP-109 (vigabatrin), a GABA aminotransferase inactivator in clinical trials to treat cocaine addiction, did not cause a decrease in visual acuity or significant peripheral visual field changes with short-term use

In addition to clearance to proceed with clinical trials, the company also received approval of the protocol from the institutional review board and scientific review committee

Oncolytics Biotech Inc., of Calgary, Alberta, said that it entered an agreement with the NCIC Clinical Trials Group at Queen's University, Kingston, Ontario, which will sponsor and conduct a randomized Phase II study of Reolysin in patients with advanced or metastatic breast cancer

Bristol-Myers Squibb Co., of New York, formed a strategic partnership with Emory University in Atlanta to conduct clinical trials involving the pharma's investigational compounds

e-Therapeutics, of Oxford, UK, said that it has started a first clinical trial evaluating its ETS2101 compound as a treatment for cancer

Sinovac Biotech Ltd., of Beijing, said that it has received a positive SFDA inspection of the three clinical trial sites in China that it is using in a Phase III study of inactivated Enterovirus 71 (EV71) vaccine against hand, foot and mouth disease

clinical trial in June testing allergy immunotherapy JRC-LAMP-Vax in subjects sensitive to Japanese red cedar pollen...Oncolytics Biotech Inc., of Calgary, Alberta, said it entered an agreement for the NCIC Clinical Trials Group at Queen's University in Kingston, Ontario, to sponsor and conduct a Phase II study of Reolysin in patients with advanced or metastatic colorectal cancer

In addition, the long-term safety and tolerability of the drug was consistent with that observed in clinical trials, with no new safety signals emerging

The next clinical trial of the defensin-mimetic antibiotic as a single dose is planned for later this year

Fibrocell Science Inc., of Exton, Pa., said pivotal clinical trial data demonstrated that Laviv (azficel-T) for nasolabial fold wrinkles is effective

Ampio Pharmaceuticals Inc., of Greenwood Village, Colo., completed enrollment of patients in a set of clinical trials to determine the usefulness of oxidation reduction potential in hospital readmission prediction, prevention and reduction in a group of patients presenting to the emergency department with chest pain...PharmAthene Inc., of Annapolis, Md., said new data based on a recent analysis of previous human clinical trial immunogenicity data and nonclinical animal study results for rPA anthrax

Threshold Pharmaceuticals Inc., of South San Francisco, received a $20 million milestone payment from Darmstadt, Germany-based Merck KGaA, which was triggered by results from a clinical trial of its drug TH-302 in pancreatic cancer