An open-label pilot phase will be followed by a three-arm, randomized, double-blind, placebo-controlled main phase comparing two different dose regimens of NOX-H94 with placebo

The randomized, double-blind, placebo-controlled trial will assess safety and efficacy of L-glutamine for sickle cell anemia and beta0-thalassemia...The primary endpoint of the double-blind study was safety and tolerability of the vaccine four weeks after the third injection

The first-in-human, double-blind, placebo-controlled trial examined the effects of single doses of Aes-103 at 300 mg, 1,000 mg, 2,000 mg and 4,000 mg or placebo in 20 healthy volunteers of African-American descent...The double-blind, placebo-controlled, single- and multiple-ascending-dose study will evaluate the safety, tolerability and pharmacokinetics of CCX872 in 40 healthy adult subjects

The randomized, double-blind, placebo-controlled, parallel-group, multicenter trial will be conducted at 60 sites in the U.S

The primary endpoint of the randomized, double-blind, vehicle-controlled study enrolling 1,655 subjects was complete cure rate at week 52

The trial, PICASSO 3, is a randomized, double-blind, placebo-controlled study evaluating progression-free survival in metastatic soft-tissue sarcoma

About 18 participants will be given two doses of PLX cells or placebo on a randomized, double-blind basis

The randomized, double-blind, placebo-controlled study will enroll 10 patients with autism to receive placebo or CNDO-201 for 12 weeks, with a goal of finding changes in repetitive behaviors, irritability, global functioning and social cognition, as well as safety...The double-blind, placebo-controlled trial enrolled 280 patients at eight centers in the U.S. Patients receive a 25-mg dose of OCA or placebo for 72 weeks

In a two-week, randomized, double-blind, placebo-controlled study, 715 patients with SAR, 6-11 years, received once-daily treatment with QNASL 80 mcg, 160 mcg or placebo

In 2008 and 2009, 20 patients suffering from moderate to severe allergies to birch pollen were enrolled in a double-blind, randomized, placebo-controlled Phase I/IIa trial and received five subcutaneous injections over two months of either AllerT (N = 15) or placebo (N = 5...Inotek Pharmaceuticals Corp., of Lexington, Mass., said its multicenter, randomized, double-blind, placebo-controlled, dose-ranging Phase II trial achieved its primary and secondary endpoints in evaluating the efficacy and

The randomized, double-blind, placebo-controlled study will evaluate a range of doses in approximately 150 patients over an eight

Ultragenyx Pharmaceutical Inc., of Novato, Calif., completed enrollment of a randomized, double-blind, placebo-controlled Phase II study of UX001 (extended-release sialic acid) in patients with hereditary inclusion body myopathy (HIBM

The study is a randomized, double-blind, double-dummy trial comparing the efficacy of dalbavancin to a regimen of vancomycin

AIM Therapeutics Inc., of Toronto, said it initiated dosing in a double-blind, placebo-controlled, crossover Phase II study evaluating the efficacy, safety, tolerability, pharmacodynamics and pharmacokinetics of oral AIM-102 in mild to moderate allergic asthma

The randomized, double-blind trial of safety and feasibility will enroll 45 patients at six centers in the U.S

In the double-blind trial, Lpath plans to dose 160 subjects who have not responded completely to a VEGF inhibitor – Lucentis (ranibizumab, Roche AG) or Avastin (bevacizumab, Roche

The randomized, double-blind trial, known as AETHERA, is comparing Adcetris against placebo in patients at high risk of residual Hodgkin lymphoma following autologous stem cell transplant

Ohr Pharmaceutical Inc., of New York, began a randomized, double-blind, placebo-controlled, Phase II trial of Squalamine Eye Drops for wet, age-related macular degeneration...The trial enrolled 15 subjects, scheduled to undergo abdominoplasty, in a double-blind dose-escalation study during which single intradermal injections were administered in a dose-dependent manner to five cohorts of three subjects each

The randomized, double-blind, placebo-controlled, escalating dose study trial enrolled 48 healthy adult volunteers...The second trial, a randomized, double-blind study, compared the immunogenicity of Flunisyn, alone or with an undisclosed adjuvant, in 48 healthy adult volunteers