The company said since it saw no adverse events at lower doses, it is continuing the Phase II dose-finding trial of incyclinide for the treatment of rosacea

In addition, DG051 was found to have good bioavailability, with low variability between subjects, and it was well tolerated at all dose levels tested, with no serious adverse events reported

TA-NIC has been through two Phase I/II studies in the UK with no unexpected adverse events and there were indications of efficacy in the treated group compared to placebo

Results showed no treatment-limiting or serious adverse events

Additionally, the ratio of plasma levels of R- to S-enantiomers of the active metabolite was lower following gel application, in comparison to a higher ratio of R-enantiomer levels known in oral products, indicating lower potential for adverse events from Anturol, which is being developed to treat symptoms of overactive bladder

The study, designed to test the oral drug administered once-daily for 28 days in 33 obese, but otherwise healthy patients, showed that PRX-07034 was well tolerated up to 600 mg once per day, with no dose-limiting toxicity identified and no serious adverse events reported

The treatment discontinuation rate due to adverse events through 12 weeks was 11 percent in telaprevir arms and 3 percent in the control arm, however

Treatment-related serious adverse events occurred in one patient in both the ferumoxytol and placebo arms...CRD5 also was well tolerated in the patient group, with the exception of the reported gastrointestinal adverse events that led to the cessation of the 5 gram dosing phase

Four of five subjects safely completed a regimen initiated 24 to 48 hours after stroke with no drug-related serious adverse events, while showing substantial recovery

The move was triggered by the initial cohorts of patients not exceeding a certain threshold related to adverse events

No significant local intolerance or drug-related serious adverse events were observed

The drug was well-tolerated across all active treatment arms, and there were no reports of drug-related serious adverse events...No-drug related serious adverse events were observed in patients who received the drug

The majority of adverse events were mild in nature, the company said...Interim results from the ongoing Phase I trial showed a dose-dependent response for GlycoPEG-GCSF vs. Neulasta, with no reported serious adverse events, Neose said

The trial, of 79 COPD patients at 12 centers in Australia, showed that the Aridol response was positive in 76.5 percent of cases, with no serious adverse events

No adverse events were reported in the Dermacyn group, although one patient in the iodine group withdrew due to topical dermatitis

The study met its primary efficacy endpoint of maintenance of visual acuity (defined as less than a three-line loss in visual acuity at three months) in 100 percent of the patients, and safety results were favorable with no drug-related serious adverse events reported

InSite Vision Inc., of Alameda, Calif., said top-line results from its Phase I study of AzaSite Plus (ISV-502), a combination antibiotic/corticosteroid product formulated in DuraSite, showed that the product was well tolerated, with no serious adverse events reported

Patients were assessed for adverse events during the one-hour retention and at follow-up visits on postoperative days eight and 15

Also, results reported the Journal of Cardiovascular Pharmacology showed that rapid transition from intravenous epoprostenol to intravenous Remodulin in 12 PAH patients was achieved with no serious adverse events, and baseline clinical status was maintained over 12 weeks