The data showed that ganetespib had clinical activity as a single agent and a good safety profile

The study also indicated a favorable safety profile and successful intercourse, as measured by SEP 3, was observed as early as 15 minutes after dosing, without restrictions on food or alcohol, the company said

QRxPharma Ltd., of Sydney, Australia, completed Study 022, an exploratory Phase III study comparing the tolerability and safety profile of MoxDuo IR to equi-analgesic doses of either morphine or oxycodone alone, with data showing that MoxDuo effectively reduced pain with less respiratory depression...The study is designed primarily to evaluate the HbA1c-lowering effects, while the cardiovascular safety profile will be monitored according to FDA guidance

Amgen Inc., of Thousand Oaks, Calif., reported interim results from a single-arm study evaluating Nplate (romiplostim) in adults with primary immune thrombocytopenia, demonstrating that the drug induced a rapid platelet response with a good safety profile in subjects with low platelet counts and bleeding symptoms

ProSavin also continued to show a favorable safety profile

The company said the double-blind study will evaluate the pharmacokinetic and safety profile of escalating doses of RG3039 in as many as 40 healthy volunteers

The company said that the open-label, dose-escalating study is sponsored in part by the Leukemia & Lymphoma Society's Therapy Acceleration Program and will be conducted in patients with relapsed or refractory AML or MDS to evaluate the safety profile, maximum tolerated dose and biologic activity of OXi4503

Can-Fite BioPharma Ltd., of Petah-Tikva, Israel, said Phase I/II interim analysis data for drug candidate CF102 in hepatocellular carcinoma showed a favorable safety profile in a patient population with primary liver cancer and Child-Pugh cirrhosis classes A and B

Stem Cell Therapeutics Corp., of Calgary, Alberta, enrolled the first patient in an open-label Phase IIa traumatic brain injury (TBI) trial testing the safety profile of NTx-428, a human chorionic gonadotropin and epoeitin alfa therapy, when administered to patients who have sustained a TBI

V-101 also demonstrated a safety profile similar to placebo

CRMD001 appears to have a favorable safety profile, according to a blinded review of the data

Vertex Pharmaceuticals Inc., of Cambridge, Mass., reported results from a Phase II study of VX-765, a caspase-1 inhibitor, in 60 patients with treatment-resistant epilepsy, with data showing a similar safety profile for VX-765 as compared to placebo, the primary endpoint

The drug's safety profile was consistent with that seen in previous studies

In that study, safety was the primary endpoint, and the drug was generally well tolerated, with a safety profile consistent to both PRE-SURGE studies. (See BioWorld Today, June 10, 2010

Overall, there was a comparable safety profile between the three groups in the study, and Posidur appeared well tolerated

The study also confirmed that the treatment had a favorable safety profile

A preliminary safety analysis showed that the safety profile was consistent with previous studies

The study will seek to determine the maximum tolerated dose and recommended Phase II dose of LOR-253, as well as the compound's safety profile, antitumor activity and pharmacokinetics

All doses were well tolerated with a favorable safety profile