In the 428-patient, randomized, double-blind, active- and placebo-controlled trial, both the 18-mg and 35-mg doses of the nonsteroidal anti-inflammatory drug met the primary objective of significant improvement in pain relief, measured by the combined differences in pain intensity at intervals over 48 hours using a visual analogue scale
The 18-month, double-blind, placebo-controlled study will be followed by an open-label extension study, with all patients taking RP103 for up to an additional 18 months
The randomized, double-blind, placebo-controlled global study will seek to demonstrate a benefit in overall survival in a chemotherapy-naive patient population
The double-blind, crossover-controlled Phase II study will compare tivozanib with sunitinib in about 160 patients...The double-blind, placebo-controlled study, being conducted under an FDA special protocol assessment, is designed to enroll more than 1,000 patients with resected Stage IIb, IIc or III melanoma in Europe and the U.S. The biotech expects to reach the recurrence-free survival endpoint by mid-2016 and file an early biologic license application
Oxygen Biotherapeutics Inc., of Morrisville, N.C., said its randomized, double-blind, placebo-controlled study of the efficacy of Dermacyte for histamine-induced pruritis showed that the drug produced a larger reduction in Visual Analogue Scale scores after standard histamine skin prick than placebo
The double-blind, multinational, placebo-controlled study evaluated ulimorelin in accelerating GI recovery in patients who had undergone partial bowel resection
The international, randomized, double-blind, placebo-controlled trial, conducted by Amgen Inc., of Thousand Oaks, Calif., is testing an intravenous formulation of omecamtiv mecarbil in patients with left ventricular systolic dysfunction who are hospitalized with acute heart failure
Pulmatrix Inc., of Lexington, Mass., reported results from a randomized, double-blind crossover trial of seven mild atopic steroid-naïve asthmatic patients who inhaled iCALM (inhaled cationic airway lining modulatory therapy), showing that the product attenuated allergen-induced bronchitis in susceptible asthmatics
The 36-month randomized, multicenter, double-blind, placebo-controlled trial will include at least 200 patients in 16 centers in Europe and Israel...The double-blind, closed-label, placebo-controlled trial is being conducted at 20 sites in five countries across Europe
Ltd., of Osaka, Japan, reported top-line results from the international, randomized, placebo-controlled, double-blind GEMINI II pivotal Phase III trial
The randomized, double-blind, placebo-controlled trial will enroll about 96 healthy volunteers in the U.S. Besides investigating the safety, tolerability and pharmacokinetic profile of ACH-3102, the trial will assess single and multiple ascending oral doses for up to 28 days...In SUSTAIN, a 24-week, multi-centered, double-blind, randomized, parallel group, placebo controlled trial, all subjects received standard of care therapy including up to 40 mg Lipitor (atorvastatin, Pfizer) or 20 mg Crestor
The double-blind, placebo-controlled study explored a single ascending dosing of up to 1,800 mg, and 15-day multiple-dose regimens of twice-daily 600 mg and 800 mg
The randomized, double-blind, placebo-controlled trial will evaluate safety and efficacy of single-agent MORAb-004 with supportive care for progression-free survival in patients with chemo-refractory metastatic colorectal cancer
The program includes an international, randomized, double-blind, placebo-controlled, parallel-group, two-year study in more than 5,000 postmenopausal women with osteoporosis
In the 428-patient, randomized, double-blind, active- and placebo-controlled trial, both the 18-mg and 35-mg doses of the nonsteroidal anti-inflammatory drug met the primary objective of significant improvement in pain relief, measured by the combined differences in pain intensity at intervals over 48 hours using a visual analogue scale