The primary endpoints will be safety and viral load reduction on day 15

Biogen Idec Inc., of Cambridge, Mass., and PDL BioPharma Inc., of Fremont, Calif., said the ongoing Phase II study of daclizumab, known as the CHOICE trial, met its primary endpoint in relapsing multiple sclerosis patients being treated with interferon beta

The primary endpoint would be levels of meal-stimulated C-peptide as a direct marker of endogenous insulin production

The primary endpoint is summed pain relief plus pain intensity scores for four hours following the initial dose

The new data showed that overall, 42 percent of patients on Flurizan showed improvement or no decline in one or more of the three primary endpoints of cognition, global function and activities of daily living, compared to 10 percent for the placebo group, indicating the drug may not only slow disease progression but also either halt that decline or even improve symptoms...The trial met its primary endpoint of improved postprandial glucose as well as secondary endpoints related to HbA1c and GLP-1

MAP Pharmaceuticals Inc., of Mountain View, Calif., said its Tempo Migraine drug candidate, an inhaled formulation of dihydroergotamine, met its primary endpoints in a Phase II program...Eighty-one percent of patients in the efavirenz arm also reached the primary endpoint

Regeneron Pharmaceuticals Inc., of Tarrytown, N.Y., reported efficacy and safety data from the Phase III study of its interleukin-1 (IL-1) Trap (rilonacept) in patients with cryopyrin-associated periodic syndromes (CAPS), showing that the product met its primary endpoint in the change in disease activity, as measured using a composite symptom score composed of daily evaluations of fever/chills, rash, fatigue, joint pain and eye redness/pain

Of those receiving 30 mg, 48 percent achieved the primary endpoint of clear or almost clear skin, compared to 28 percent in the 10 mg group and 17 percent in the placebo group

Genta Inc., of Berkeley Heights, N.J., said findings from a Phase III trial of Genasense (oblimersen sodium) injection in relapsed or refractory chronic lymphocytic leukemia achieved its primary endpoint, which was defined as a statistically significant increase in the proportion of patients receiving Genasense with fludarabine plus cyclophosphamide chemotherapy who achieved a complete or nodular partial response (17 percent) over those receiving chemotherapy alone (7 percent.) Those findings

Data from the 55-patient trial showed that Chondrogen met its primary endpoint of demonstrating safety, but did not show a statistically significant increase in the volume of meniscus as compared to placebo...The primary endpoint is safety

Favrille expects primary endpoint data from an ongoing pivotal Phase III trial of FavId following Rituxan in NHL in the fourth quarter of 2007

They will receive 5,000 mg/m2 of glufosfamide every three weeks for up to six cycles, and the primary endpoint will measure objective response rates

They will be randomized into three trial arms - two groups receiving dosing regimens of orally administered MitoQ and one receiving placebo - and the primary endpoint will measure the change in the level of alanine aminotransferase

Patients receiving Raptiva in the randomized, double-blind, placebo-controlled, 12-week trial demonstrated a statistically significant improvement in the primary endpoint, a rating of clear (0) according to the Physician's Global Assessment

The primary endpoint is a reduction of visceral adipose tissue, which is a risk factor for cardiovascular disease and type 2 diabetes

The primary endpoint is improvement of BPH symptoms

The primary endpoint is defined as a statistically and clinically significant increase in the time to disease progression as measured by the Expanded Disability Status Scale...The trial will involve 240 subjects with papulopustular rosacea, and the primary endpoint is to determine the product's efficacy in reducing the number of inflammatory lesions

Anesiva Inc., of South San Francisco, said data from a Phase I study of 1207, a topical anesthetic for neuropathic patients, achieved the primary endpoint of safety and tolerability in a healthy volunteer population, though no clear anesthetic effect was demonstrated

The trial's primary endpoint is to eliminate or delay the progression of osteonecrosis, which will be measured by MRI and X-ray, and patients will be followed for 24 months past treatment