The primary endpoint is the 24-hour red blood cell recovery post-transfusion...The primary endpoint - the reduction in the Composite Pelvic Sign and Symptoms Score - showed a greater than 5 point reduction in the higher dose group, but a more striking reduction, the company said, was seen in the "worst pain" endpoint as measured by the Visual Analogue Scale
The primary endpoint is the percentage of patients at least moderately improved for each treatment group in a patient-reported Global Response Assessment...The primary endpoint is restoration of function to occluded central venous catheters at 15 minutes...The primary endpoint is avoidance of open vascular surgery within 30 days of treatment
The primary endpoint is survival, and secondary endpoints include response rate in the brain...The study's primary endpoint is to demonstrate Oxycyte's ability to increase brain oxygen tension and favorably affect other brain chemistries that impact clinical outcome in head injury patients
The randomized, double-blind, placebo-controlled trial will enroll about 72 patients, and the primary endpoint is to assess the effect of PRX-08066 compared to placebo on systolic pulmonary artery pressure following two weeks of treatment
Patients receiving doses of 130 mg per cycle of ozarelix have shown the greatest continuous suppression of testosterone, the primary endpoint, where patients remained suppressed to castration until at least day 85
The open-label study will evaluate patient response for one year according to several primary endpoints, including changes in hemoglobin, platelet levels and spleen volume
UCB SA, of Brussels, Belgium, reported positive Phase II data showing that Cimzia (certolizumab pegol, CDP870) met its co-primary endpoints in reducing psoriasis following 12 weeks of treatment
The six-month, multicenter, double-blind controlled trial will enroll up to 120 ALS patients, and the primary endpoint is the change in the revised ALS Functional Rating Scale...The primary endpoint is the prevention of ulcerative lesions
Alexion Pharmaceuticals Inc., of Cheshire, Conn., said preliminary Phase III results showed that pexelizumab failed to achieve a statistically significant reduction in mortality at 30 days following primary percutaneous coronary intervention (angioplasty), the APEX-AMI trial's primary endpoint
The primary endpoint is progression-free survival, and secondary endpoints include response rates, overall survival and the incidence and severity of adverse events
The Phase III trial is expected to enroll about 1,400 men, and the primary endpoint is a reduction in vertebral fractures...Patients received Nebido via intramuscular injection every 12 weeks, and the primary endpoint is average serum testosterone levels at steady state, measured after the fourth injection
A 114-patient Phase IIb trial, which looked at cocaine users who also were on methadone maintenance therapy for heroin addiction, did not achieve its primary endpoint in improving cocaine abstinence for three consecutive weeks, but results indicated that twice as many patients in the treatment group achieved 50 percent or greater increase in cocaine-free days...The approval is based on Phase III data of 829 patients that showed that Avastin plus the 5-FU-based chemotherapy regimen known as FOLFOX4
All met the primary endpoint of reducing the occurrence of moderate or severe cerebral vasospasm, as measured by cerebral angiography at day nine post-aneurysm rupture compared to placebo...The primary endpoint is the objective response rate
Indevus Pharmaceuticals Inc., of Lexington, Mass., said Phase III data showed that Sanctura XR met its primary endpoints in patients with overactive bladder: reduction in frequency of urination and reduction in number of urge incontinent episodes...The primary endpoint will be the man change in HIV RNA viral load (log10) after 24 weeks in the active arm compared to the placebo arm
The primary endpoint will be hematologic response rate, and cytogenetic response rate will be the secondary endpoint...The trial is expected to enroll about 300 patients with a history of failure with BCG treatment, and measure time to recurrence as the primary endpoint
The primary endpoint is the 24-hour red blood cell recovery post-transfusion...The primary endpoint - the reduction in the Composite Pelvic Sign and Symptoms Score - showed a greater than 5 point reduction in the higher dose group, but a more striking reduction, the company said, was seen in the "worst pain" endpoint as measured by the Visual Analogue Scale