In addition to EC145, patients in the study also will be treated with a molecular imaging agent, EC20, also developed by Endocyte, which is designed to allow clinicians to identify tumors that overexpress the folate receptor

As a result of the discontinuation, all patients on the study drug will be moved to the standard of care

The 10-patient study uses Cytori's Celution 800 System to process and extract the patients' own adipose tissue-derived stem and regenerative cells at the time of surgery

Those results are now reinforced by those additional findings indicating, in part, that patients in the study quickly returned to their pretreatment level of atrial fibrillation once the treatment ended

The 510-patient study met both the primary and secondary endpoints, and Zemiva was well tolerated, with no serious adverse effects

The 469-patient study consisted of an initial four-week, double-blind phase followed by an eight-week open-label phase

Patients in the study will be followed for 12 months post-treatment

Anadys expects to enroll approximately 30 patients in the study of ANA598 at doses of 200 mg bid (twice-a-day), 400 mg bid and 800 mg bid

After 14 days of bevirimat treatment given twice daily at doses of 200 mg or 300 mg, 100 percent of 32 treatment-naive and treatment-experienced patients in Study 204 had bevirimat plasma concentrations well above the previously identified minimum target of 20I 1/4g/mL

However, due to the small number of patients in the study, neither of these endpoints were statistically significant

Patients in the study are treated once daily with one of three dose levels of VIA-2291, a small-molecule drug that targets inflammation in the blood vessel wall, or placebo

Napo Pharmaceuticals Inc., of San Francisco, said results from a 100-patient study of crofelemer in severely ill cholera patients in conjunction with an antibiotic and rehydration therapy showed that the drug, dosed at 125 mg every six hours, reduced the amount of stool volume output normalized to a body weight by 32 percent in the first six-hour period

The 80-patient study is evaluating daily TT-223 treatments for 12 weeks with a six-month follow-up

The primary objective of the 14-patient study is to measure tumor responses and duration of response, as well as to describe any evidence of antitumor activity

However, a post hoc analysis of patients with a history of aura, which represented 47 percent of all patients in the study, demonstrated statistically significantly sustained pain relief for up to 24 hours without rebound headache, with 22 percent, 48 percent and 68 percent of patients experiencing relief compared to placebo at two hours, four hours and six hours, respectively

BMS-099, a 676-patient study, was not powered to detect an improvement in overall survival with the same degree of statistical precision as was the larger 1,125-patient pivotal FLEX Phase III study conducted by Merck KGaA, of Darmstadt, Germany

Data from the 23-patient study showed that, at both dose levels given, PTC124 was associated with statistically significant improvements in CFTR-mediated chloride transport with more than half of the patients entering the normal range during at least one treatment course

The 80-patient study is designed to test the safety and tolerability of multiple subcutaneous dose schedules of MEDI-545 or placebo in adults with moderate to severe active lupus

The three-arm, 180-patient study is designed to determine whether combination therapy is superior to either Vidaza or MGCD0103 alone