Thus, IQP-0410 can be dosed once per day, and possesses a highly positive safety profile, which suggests it will be amenable for use in women of child-bearing years, the company said
Those results showed the product candidate to have an excellent safety profile and suggested that it may be suitable for administration on a once-monthly basis
Algeta ASA, of Oslo, Norway, said results of its BC1-04 Phase II study evaluating Alpharadin (radium-223) as a treatment for bone metastases in patients with hormone-refractory prostate cancer showed strong evidence that Alpharadin can prolong patient survival times, improve quality of life and offer a placebo-like safety profile
Theratechnologies Inc., of Montreal, reported 52-week results of its confirmatory Phase III trial, evaluating the long-term safety profile of its lead compound, tesamorelin, in patients with HIV-associated lipodystrophy...The results showed are consistent with the safety profile observed in the first Phase III trial
Data from the placebo-controlled, single-ascending dose trial of a single intravenous administration of NU206 in 32 healthy male volunteers showed that the compound had a favorable safety profile, no serious adverse events were observed and pharmacokinetics were predictable
The Phase I portion will assess the safety profile and test pharmacokinetic and pharmacodynamic activities, while the Phase II component is designed to test the clinical benefits
Bioniche Life Sciences Inc., of Belleville, Ontario, presented data showing its Mycobacterial Cell Wall-DNA Complex (Urocidin) with an excellent safety profile in older patients...The safety profile of Avastin was consistent with previous experience, and no new safety signals were observed
Avexa Ltd., of Melbourne, Australia, said 48-week data from a Phase IIb trial showed that apricitabine provided significant and durable antiviral activity over the treatment period in treatment-experienced HIV patients, with a favorable safety profile and no evidence of resistance development
Bavarian Nordic A/S, of Kvistgard, Denmark, completed a safety report from a large Phase II study with Imvamune in HIV-infected subjects, which confirmed an excellent safety profile for the smallpox vaccine
The presentation reported the absence of serious, dose-limiting adverse events in the study and concluded that the data demonstrate an acceptable safety profile for multiple subcutaneous doses of MEDI-528
HUYA Bioscience International LLC, of San Diego, and Chipscreen Biosciences Ltd., of Shenzhen, China, said a Phase I trial of Chidamide (HBI-8000) demonstrated best-in-class pharmacokinetics, biomarker and safety profiles, as well as activity against T-lymphoma and other tumor types...Based on its mechanism of action and safety profile in AD patients, the company said, HF0220 may have synergistic effects in combination with currently marketed anti-dementia drugs
Positive results for other study endpoints, including increased median progression-free survival and tumor stabilization, were shown, and the drug's safety profile was favorable
Kamada Ltd., of Ness Ziona, Israel, said data from its Phase II study evaluating inhaled alpha-1 antitrypsin delivered via an investigational eFlow nebulizer system (PARI Pharma GmbH) in the treatment of cystic fibrosis, demonstrated that the product has an excellent safety profile and showed promising signs of efficacy, as indicated by a reduction in lung inflammation
The first trials comprise ascending dose studies to determine the maximum tolerated dose and to assess the pharmacokinetics and overall safety profile of SB1518
Thus, IQP-0410 can be dosed once per day, and possesses a highly positive safety profile, which suggests it will be amenable for use in women of child-bearing years, the company said