Those findings, presented at the Obesity Society meeting in Washington, add to the top-line data presented earlier this year, which showed a significant weight loss in patients receiving one year of treatment with lorcaserin. (See BioWorld Today, Sept. 21, 2009...Top-line data from COR-I and COR-II were reported in July. (See BioWorld Today, July 21, 2009

Sangamo BioSciences Inc., of Richmond, Calif., said top-line data showed that its SB-509 demonstrated statistical significance in a Phase II diabetic neuropathy trial

Top-line data are expected in mid-December and, if positive, will form the basis for a new drug application filing in the second quarter of 2010

Alkermes Inc., of Cambridge, Mass., reported top-line data from two Phase I trials of ALKS 33, an oral opioid modulator to treat addiction and other central nervous system disorders, showing that the drug was well tolerated and successfully blocked the effects of an opioid, with a duration of action that supports once-daily dosing

Nektar Therapeutics Inc., of San Carlos, Calif., said top-line data from a Phase II trial showed that of NKTR-118, an oral peripherally-acting opioid antagonist, increased spontaneous bowel movements over the baseline period, the study's primary endpoint

Transdel Pharmaceuticals Inc., of La Jolla, Calif., reported positive top-line data from a Phase III trial of Ketotransdel, a topical formulation of nonsteroidal anti-inflammatory drug ketoprofen, showing that the study achieved statistical significance in the primary endpoint in the per protocol analysis of 252 patients

Top-line data are expected late this year, and detailed data will be presented at a scientific conference next year

Top-line data are expected by mid-2010

Top-line data from the first trial are expected later this month

Array BioPharma Inc., of Boulder, Colo., reported top-line data from a Phase I trial of ARRY-403, a small-molecule glucokinase activator, in Type II diabetics, showing that it met its primary and secondary endpoints of safety, pharmacokinetics and glucose control

Top-line data in each of the pivotal trials demonstrated that the drug met its primary objective of noninferiority and achieved high clinical cure rates compared to ceftriaxone in patients with moderate to severe pneumonia requiring hospitalization

Top-line data from the trial were submitted to the FDA, and the company is in the process of finalizing the Phase III program

The company expects to announce top-line data in the first half of 2010

Preliminary top-line data are expected to become available in the fourth quarter for both studies

The company previously reported top-line data from the trial showing that Corlux plus Risperdal resulted in statistically significant reduction in weight gain compared to Risperdal alone

Top-line data were reported late last year, and final data have been submitted for presentation at the American Diabetes Association 2009 scientific sessions. (See BioWorld Today, Dec. 5, 2008

Arpida Ltd., of Reinach, Switzerland, reported top-line data of its Phase II intravenous-to-oral switch trial, which showed clinical cure rates of more than 90 percent following the step-down therapy with oral iclaprim administered after two days of initial treatment with intravenous vancomycin in patients with complicated skin and skin structure infections (cSSSI...PrGCD also is being studied in a pivotal, Phase III trial in naïve Gaucher's disease patients, with top-line data expected in the

Rib-X Pharmaceuticals Inc., of New Haven, Conn., reported positive top-line data from a Phase II trial of delafloxacin (RX-3341), an intravenous formulation of its anionic quinolone antibiotic, which showed that both doses (300 mg BID and 450 mg BID) were as efficacious as the FDA-approved dosing regimen for Tygacil (tigecycline, Wyeth) in complicated skin and skin structure infections

Top-line data is expected in the first half of 2009