The compound suppressed cancer progression in an animal model of melanoma

Ltd., said Harvard Medical School presented data at the Association for Research in Vision and Ophthalmology conference in Seattle showing a major link between vascular endothelial growth factor (VEGF)-C levels and age-related macular degeneration (AMD) and that assessment of Opthea's drug development candidate, VGX-300 (a soluble form of VEGF receptor-3 that blocks VEGF-C and VEGF-D) in animal models of wet AMD confirmed its potential as a new therapy for the disease

Inovio Pharmaceuticals Inc., of Blue Bell, Pa., said its SynCon DNA vaccine against Ebola and Marburg filoviruses induced strong and broad immune responses and demonstrated 100 percent protection against death following a challenge with multiple variants of the pathogens in two animal models

Pluristem Therapeutics Inc., of Haifa, Israel, said its PLacental eXpanded (PLX) cells tested in preclinical animal models of preeclampsia effectively improved several parameters of the disease

Acceleron presented data on the effects of its investigational protein therapeutic, ACE-536, on correcting anemia and ineffective erythropoiesis in an animal model

Medicago's technology requires only the genetic sequence of the viral strain to produce an influenza vaccine, and the H7 VLP is now being purified in preparation for immunogenicity studies in animal models

Cel-Sci Corp., of Vienna, Va., reported findings from an efficacy study in a second animal model of rheumatoid arthritis (RA) using its LEAPS technology

Atox Bio Ltd., of Ness Ziona, Israel, said data from an animal model of necrotizing soft-tissue infection, also known as flesh-eating bacteria, demonstrated that the administration of a single dose of AB103, given several hours after infection even without antibiotics, increased survival in animals and reduced tissue necrosis, inflammation and bacterial burden at the site of infection without compromising the immune response

Atox Bio Ltd., of Ness Ziona, Israel, said data from an animal model of necrotizing soft-tissue infection, also known as flesh-eating bacteria, demonstrated that the administration of a single dose of AB103, given several hours after infection even without antibiotics, increased survival in animals and reduced tissue necrosis, inflammation and bacterial burden at the site of infection without compromising the immune response...Critical Outcome Technologies Inc., of London, Ontario, completed a

Data also showed SG100 can be safely applied in a relevant animal model

The studies were carried out in animal models

Clinigen Group plc, of Burton-on-Trent, UK, and Theravance Inc., of South San Francisco, entered an exclusive commercialization agreement in the European Union and certain other countries located in Europe for Vibativ (telavancin) in nosocomial pneumonia, including ventilator-associated pneumonia, known or suspected to be caused by methicillin-resistant Staphylococcus aureus, when other alternatives are not suitable...In other news, Elan said its Tysabri (natalizumab) restructuring transaction is

Prana Biotechnology Ltd., of Melbourne, Australia, said PBT434 was found to reduce the aggregation and accumulation of alpha-synuclein, a key protein in Parkinson's disease, in multiple transgenic animal models of the disease

iBio Inc., of Newark, Del., will proceed with development of its antibody candidate for influenza following demonstration of safety and therapeutic efficacy in animal models, including models of H5N1 influenza

The collaboration will determine whether PRO 140 can prevent or significantly diminish a primary HIV infection in an animal model

The agreement covers evaluation of the proteins by in vitro and animal models to characterize the mechanism of action for Trichuris suis ova (CNDO-201) leading to identification of potential drug candidates

The poster highlighted data demonstrating the in vivo memory-enhancing properties in two animal models of cognitive impairment as well as data on the action of BNC375 on the receptor

The poster highlighted data demonstrating the in vivo memory-enhancing properties in two animal models of cognitive impairment as well as data on the action of BNC375 on the receptor

The company previously reported that an animal model of oral influenza candidate FluCide showed superior efficacy to Tamiflu (oseltamivir, Roche AG) against an H3N2 influenza virus strain, similar to the current dominant strain of influenza