To date, Celltrion and Hospira have identified only two products from the alliance – Remsima, a biosimilar version of autoimmune drug Remicade (infliximab, Johnson & Johnson), which won approval as the first biosimilar monoclonal antibody last year in Korea, and a biosimilar version of breast cancer drug Herceptin (trastuzumab, Roche

To date, Celltrion and Hospira have identified only two products from the alliance – Remsima, a biosimilar version of autoimmune drug Remicade (infliximab, Johnson & Johnson), which won approval as the first biosimilar monoclonal antibody last year in Korea, and a biosimilar version of breast cancer drug Herceptin (trastuzumab, Roche). (See BioWorld Today, April 19, 2013

In other news, law firm Bronstein, Gewirtz & Grossman LLC, of New York, said it is investigating claims on behalf of purchasers of Spectrum securities, after shares (NASDAQ:SPPI) fell as much as 38 percent on March 13 on news that the company slashed its revenue projections for colon cancer drug Fusilev (levoleucovorin

Ablynx NV, of Ghent, Belgium, and Spirogen Ltd., of London, inked a research collaboration to evaluate the potential of a cancer drug conjugate combining Spirogen's cytotoxic drugs, pyrrolobenzodiazepines and associated linker technology, with Nanobodies generated using Ablynx's technology platform

Ablynx NV, of Ghent, Belgium, and Spirogen Ltd., of London, inked a research collaboration to evaluate the potential of a cancer drug conjugate combining Spirogen's cytotoxic drugs, pyrrolobenzodiazepines and associated linker technology, with Nanobodies generated using Ablynx's technology platform

The FDA approved the first generic version of Johnson & Johnson's Doxil (doxorubicin hydrochloride liposome injection), an ovarian cancer drug on the FDA's drug shortage list

Based on the observed safety of the agent and its specificity for binding to diseased cells, the company is advancing both the diagnostic imaging agent and the corresponding therapeutic, EC1069, a PSMA-targeted small-molecule drug conjugate linked with cancer drug tubulysin

Genentech, of South San Francisco, a member of the Roche Group, said the FDA gave its go-ahead to a new use of already approved cancer drug Avastin (bevacizumab) in combination with fluoropyrimidine-based irinotecan or oxaliplatin chemotherapy for people with metastatic colorectal cancer (mCRC

When combined with an FDA-approved cancer drug, the technology is designed to allow for the creation of a range of next-generation drug products

Lorus Therapeutics Inc., of Toronto, signed a collaboration agreement with Brock University of St. Catherines, Ontario, for the development of cancer drugs based on chemical derivatives of the natural compound pancratistatin

Earlier this year, Spectrum acquired Allos Therapeutics Inc., of Westminster, Colo., following failure of Spectrum's cancer drug apaziquone in two Phase III trials. (See BioWorld Today, April 6, 2012

Bio-Path Holdings Inc., of Houston, initiated development of its lead cancer drug BP-100-1.01 (Liposomal Grb-2) to treat triple negative breast cancer (TNBC) and inflammatory breast cancer (IBC), two cancers with relatively high mortality rates

The first stage of the complex includes separate plants for oral and injected cancer drugs, plus a GMP bio pilot plant with a 500 L cell culture capacity

The first stage of the complex includes separate plants for oral and injected cancer drugs, plus a GMP bio pilot plant with a 500 L cell culture capacity

ValiRx plc, of London, said it raised £2.03 million (US$3.3 million) in a placement to support work on lead cancer drug VAL201

Ironwood plans to initiate Phase I studies in healthy volunteers to assess the pharmacokinetics of IW-2143...Immune Pharmaceuticals Ltd., of Herzlyia-Pituach, Israel, and EpiCept Corp., of Tarrytown, N.Y., entered a merger agreement, anticipated to close in the first quarter of 2013, that will create a combined company – Immune Pharmaceuticals Inc. – focused on developing antibody therapeutics and other targeted drugs

Morphotek Inc., of Exton, Pa., a subsidiary of Eisai Inc., said it has been granted FDA orphan drug designation for its investigational cancer drug, amatuximab (MORAb-009), a chimeric IgG1 antibody that targets a cell surface glycoprotein, mesothelin

A separate presentation featuring PharmaMar's other cancer drug, Yondelis (trabectidin), in combination with olaparib (AZD-2281), a PARP inhibitor from London-based AstraZeneca plc, showed that the two drugs had a synergistic effect on tumor lines, including breast cancer cells with and without BRCA-1 gene expression

The partners will discover and develop new cancer drugs in collaboration with researchers at the Cancer Research UK Drug Discovery Program at the Northern Institute for Cancer Research (NICR...Astex will provide £1 million (US$1.6 million) funding annually to Newcastle University to support research across biology, chemistry, pharmacology and imaging at the NICR to identify and develop new cancer drugs and associated biomarkers to develop tests to determine which patients to treat and if new drugs