Ligand Pharmaceuticals Inc., of San Diego, completed its acquisition of Glycomed Inc., of Alameda, Calif...The company also completed a Phase I study of pagoclone to treat anxiety. * Biomune Systems Inc., of Salt Lake City, said in vivo studies of its drug may retard the growth of prostate cancer tumors. * Cytogen Corp., of Princeton, N.J., started trials using OncoScint CR/OV, a monoclonal-based imaging agent, for preoperative staging of breast cancer. * Telios Pharmaceuticals Inc., of San Diego

T Cell Sciences Inc., of Needham, Mass., said its subsidiary, T Cell Diagnostics Inc., received clearance to market the TRAx CD4 Test Kit as a method for enumerating CD4 T cells. * Medco Research Inc., of Research Triangle Park, N.C., and Fujisawa USA Inc., of Deerfield, Ill., said the FDA granted marketing clearance for Adenoscan (adenosine injection), as a coronary vasodilator for use with radioactive thallium imaging in patients unable to exercise adequately. * Genta Inc., of San Diego

Bristol Myers' Taxol is approved for ovarian and breast cancers in the U.S. * Cytel Corp., of San Diego, licensed technology for the enzymatic synthesis of carbohydrates from Scripps Research Institute, of La Jolla, Calif...GenESA is designed to diagnosis coronary artery disease in association with other devices in patients who cannot exercise adequately. * Genta Inc., of San Diego, expanded its joint venture, Genta Jago, with Switzerland-based Jagotec AG to develop controlled-release oral

and Alpha 1 Biomedicals Inc., reacquired Far Eastern marketing rights to HGP-30, a potential HIV vaccine/treatment. * Genta Inc., of San Diego, completed a previously announced offering of 4.7 million shares of common stock to overseas institutional investors, grossing $8 million. * Neurex Corp., of Menlo Park, Calif., was given an OK by the FDA to resume Phase II trials of SNX-111, administered intravenously, for prevention of brain damage

Other News To Note Centocor Inc., of Malvern, Pa., said ReoPro, an anti-platelet drug, has been cleared for marketing in Germany and France for high-risk angioplasty patients

The company said it intends to file for approval of the test for use by consumers this year. * Cortecs International Ltd., of London, entered an agreement with Denmark-based Osteometer BioTech A/S for development of a test to detect collagen breakdown, which is an indicator of osteoporosis. * Gensia Inc., of San Diego, and Atrix Laboratories Inc., of Fort Collins, Colo., have agreed to co-develop a treatment of solid tumor cancers based on Atrix's Atrigel drug delivery system...and its

The company said it intends to file for approval of the test for use by consumers this year. * Cortecs International Ltd., of London, entered an agreement with Denmark-based Osteometer BioTech A/S for development of a test to detect collagen breakdown, which is an indicator of osteoporosis. * Gensia Inc., of San Diego, and Atrix Laboratories Inc., of Fort Collins, Colo., have agreed to co-develop a treatment of solid tumor cancers based on Atrix's Atrigel drug delivery system...and its

The five monkeys resisted infection and remained seronegative more than four months after inoculation. * Syntex Corp., of Palo Alto, Calif., will change the name of its operations here to Roche Bioscience effective July 5, reflecting its research focus and acquisition last fall by Roche Holding Ltd., of Basel, Switzerland. * Viagene Inc., of San Diego, and Chiron Corp., of Emeryville, Calif., are the targets of a lawsuit filed by a Viagene shareholder related to the companies' merger April 24

Cambridge Neuroscience Inc., of Cambridge, Mass., started a placebo-controlled study of Cerestat in stroke patients, who will be treated with fixed rather than weight-adjusted doses of the drug. * Genetronics Biomedical Ltd., of San Diego, signed a contract to support gene therapy studies being conducted at The Toronto Hospital...It will involve HIV- negative people who participated in a previous study. * Researchers at Johns Hopkins School of Medicine, of Baltimore, and Matritech Inc., of

Ethyol also has been cleared for marketing in France, Spain, Luxembourg and the U.K. * Cambridge Neuroscience Inc., of Cambridge, Mass., started a placebo-controlled study of Cerestat in stroke patients, who will be treated with fixed rather than weight-adjusted doses of the drug. * Genetronics Biomedical Ltd., of San Diego, signed a contract to support gene therapy studies being conducted at The Toronto Hospital

The company, a subsidiary of Interneuron Pharmaceuticals, also of Lexington, said the trials are the first beta blocker studies aimed at measuring the impact of the drug on mortality in congestive heart failure. * Vical Inc., of San Diego, began Phase I/II trials of its Leuvectin cancer gene therapy at the Arizona Cancer Center in Tucson...Those compounds will undergo additional tests in prostate cancer cell lines at Roswell Park Memorial Cancer Institute in Buffalo, N.Y. * CytoProbe Corp., of San

Results of the study are expected by the end of 1995. * Vical Inc., of San Diego, began Phase I/II trials of its Leuvectin cancer gene therapy at the Arizona Cancer Center in Tucson...Those compounds will undergo additional tests in prostate cancer cell lines at Roswell Park Memorial Cancer Institute in Buffalo, N.Y. * CytoProbe Corp., of San Diego, raised $1 million in a private placement to help fund continued development of its three major medical device products. * Matritech Inc., of

Results of the study are expected by the end of 1995. * Vical Inc., of San Diego, began Phase I/II trials of its Leuvectin cancer gene therapy at the Arizona Cancer Center in Tucson...Those compounds will undergo additional tests in prostate cancer cell lines at Roswell Park Memorial Cancer Institute in Buffalo. * CytoProbe Corp., of San Diego, raised $1 million in a private placement to help fund continued development of its three major medical device products. (c) 1997 American Health

Fourteen patients with metastatic breast cancer will participate and enrollment is expected to be completed by the end of this year. * Gensia Inc., of San Diego, received FDA approval for an abbreviated new drug application for amphotericin B for use as an intravenous anti-fungal therapeutic. * Houghton Pharmaceuticals Inc., of San Diego, started clinical trials of HP 228, a cytokine restraining agent, to reduce the negative side effects of chemotherapy in advanced cancer patients

Hoffmann-La Roche is a subsidiary of Switzerland-based Roche Holdings Ltd. * Gensia Inc., of San Diego, received product licenses in Germany and Luxembourg to market the GenESA System for diagnosis of coronary artery disease in conjunction with electrocardiography, echocardiography and radionuclide imaging for patients who cannot exercise. * Interferon Sciences Inc., of New Brunswick, N.J., said Mexico approved the company's Interferon Alfa-n3 for treatment of refractory or recurrent external

ESCAgenetics now is being traded on the Electronic Bulletin Board under the symbol, ESNG. * Vical Inc., of San Diego, said Phase I/II trials of its anti-cancer drug, Allovectin-7, showed it was safe and that the product successfully transferred to tumor lesions a gene that encodes a mismatched transplantation antigen, HLA-B7...Results were not yet available. * Mycogen Inc., of San Diego, received approval to produce planting seeds for corn hybrids that are genetically engineered to resist insect

ESCAgenetics now is being traded on the Electronic Bulletin Board under the symbol, ESNG. * Vical Inc., of San Diego, said Phase I/II trials of its anti-cancer drug, Allovectin-7, showed it was safe and that the product successfully transferred to tumor lesions a gene that encodes a mismatched transplantation antigen, HLA-B7

Alpha Therapeutic Corp., of Los Angeles, is conducting the trials. * Dura Pharmaceuticals Inc., of San Diego, acquired Health Script and its affiliates in Denver for cash and warrants

Advanced Tissue Sciences Inc., of La Jolla, Calif., said Stratum Laboratories International, of San Diego, has agreed to pay up to $5 million to acquire Advanced Tissue Sciences' In Vitro Laboratory Testing business