Unigene Laboratories Inc., of Boonton, N.J., signed a clinical manufacturing services agreement with privately held Stealth Peptides Inc., of Boston

Columbia Laboratories Inc., of Livingston, N.J., said it's cutting its work force by about 42 percent, from 24 employees to 14 employees, primarily in R&D and general administrative positions, to lower costs and better align operating expenses with revenues

Columbia Laboratories Inc., of Livingston, N.J., said partner Watson Pharmaceuticals Inc., of Parsippany, N.J., confirmed that it received a complete response letter for progesterone vaginal gel 8 percent for reducing the risk of preterm birth in women with a singleton gestation and a short uterine cervical length in the midtrimester of pregnancy

Forest Laboratories Inc., of New York, said it received European approval to market Colobreathe (dry powder colistimethate sodium for inhalation) for treating cystic fibrosis patients, ages 6 and older, with chronic lung infections caused by P

Impax Pharmaceuticals, of Hayward, Calif., the branded products division of Impax Laboratories Inc., said the FDA accepted for filing its new drug application for IPX066 in idiopathic Parkinson's disease

Gedeon Richter plc, of Budapest, Hungary, and Forest Laboratories Inc., of New York, reported top-line results from a Phase III trial of cariprazine (RHG-188), an antipsychotic agent, in patients with acute mania associated with bipolar I disorder

Columbia Laboratories Inc., of Livingston, N.J, said it transferred to Watson Pharmaceuticals Inc., of Parsippany, N.J., the new drug application for progesterone vaginal gel 8 percent for use in the reduction of risk of preterm birth in women with a singleton gestation and a short uterine cervical length in mid-trimester of pregnancy

Inviragen Inc., of Fort Collins, Colo., signed a deal with contract research and manufacturing organization Advanced BioScience Laboratories Inc., of Rockville, Md., for production and characterization of a master virus seed stock for use in Inviragen's development of a vaccine against plague

Impax Pharmaceuticals, of Hayward, Calif., the branded business unit of Impax Laboratories Inc., said it licensed from London-based AstraZeneca plc exclusive U.S

Impax Pharmaceuticals, of Hayward, Calif., the branded products division of Impax Laboratories Inc., submitted a new drug application for IPX066 to the FDA to treat idiopathic Parkinson's disease

The SEC charged Stiefel Laboratories Inc., a subsidiary of GlaxoSmithKline plc (GSK), of London, and Charles Stiefel, its former chairman and CEO, with defrauding employees and other shareholders by buying back their stock at severely undervalued prices

Valeant Pharmaceuticals International Inc., of Mississauga, Ontario, said that it completed its previously announced acquisition of Dermik Laboratories Inc., a dermatology unit of Sanofi SA, of Paris

The SEC charged Stiefel Laboratories Inc., a subsidiary of GlaxoSmithKline plc (GSK), of London, and Charles Steifel, its former chairman and CEO, with defrauding employees and other shareholders by buying back their stock at severely undervalued prices

Unigene Laboratories Inc., of Boonton, N.J., said London-based GlaxoSmithKline plc decided not to proceed with development of Unigene's oral recombinant parathyroid hormone for osteoporosis

In other news, Almirall and Forest Laboratories Inc., of New York, began a Phase III trial of a fixed-dose combination of aclidinium bromide and formoterol fumarate via the Genuair inhaler for chronic obstructive pulmonary disease (COPD...Ben Venue Laboratories Inc., a division of Boehringer Ingelheim GmbH, of Ingelheim, Germany, voluntarily suspended the manufacture and distribution of drug products from its Bedford, Ohio, facility, which produces New Brunswick, N.J.-based Johnson & Johnson's

Ben Venue Laboratories Inc., a division of Boehringer Ingelheim GmbH, of Ingelheim, Germany, voluntarily suspended the manufacture and distribution of drug products from its Bedford, Ohio, facility, which produces New Brunswick, N.J.-based Johnson & Johnson's cancer drug Doxil, after an internal document review suggested routine preventive maintenance and requalification of certain manufacturing equipment were overdue...Milnacipran was approved in 2009 in the U.S., where it is marketed as Savella

Columbia Laboratories Inc., of Livingston, N.J., and Watson Pharmaceuticals Inc., of Parsippany, N.J., said the FDA's Advisory Committee for Reproductive Health Drugs plans to review Columbia's new drug application (NDA) for Prochieve, a progesterone vaginal gel for the reduction of risk of preterm birth in women with short uterine cervical length, regardless of other risk factors, in the mid-trimester of pregnancy

The acquisition includes the manufacturing assets for dinoprostone marketed by Forest Laboratories Inc

Acton also is developing Aerospan (flunisolide HFA) inhalation aerosol, an FDA-approved, HFA-propelled aerosol inhaled corticosteroid for the treatment of asthma in-licensed from Forest Laboratories Inc., of New York