Lpath Inc., of San Diego, disclosed a 1-for-7 reverse split of the company's issued and outstanding Class A common stock and a corresponding decrease in the number of its authorized shares

Celladon Corp., of San Diego, and Lonza, of Basel, Switzerland, entered a process transfer and GMP manufacturing agreement...Optimer Pharmaceuticals Inc., of San Diego, implemented a push to accelerate and expand patient access to Dificid (fidaxomicin) tablets through a hospital-contracting initiative, and separately launched a new project analyzing the burden of Clostridium difficile infection

Apricus Biosciences Inc., of San Diego, said it intends to file a new drug submission (NDS) in Canada for MycoVa, its topical treatment for onychomycosis...Medistem Inc., of San Diego, is collaborating with Superview Biotechnology Co

Cytori Therapeutics Inc., of San Diego, was awarded a contract that could be valued at up to $106 million if all options are executed, by the Department of Health and Human Services' Biomedical Advanced Research and Development Authority

Amarantus Biosciences Inc., of Sunnyvale, Calif., said positive, peer-reviewed efficacy data for the anti-apoptotic therapeutic protein MANF in an animal model of myocardial infarction were published in The Journal of Biological Chemistry by the Glembotski Lab at the San Diego State University's biology department and the SDSU Heart Institute

Santaris Pharma A/S, of Hoersholm, Denmark, said the federal court in the Southern District of California granted Santaris significant relief in the patent infringement lawsuit brought by Isis Pharmaceuticals Inc., of San Diego

Bionomics Ltd., of Adelaide, Australia, has acquired the private biotechnology company Eclipse Therapeutics Inc., of San Diego, in a $10 million deal

Bionomics Ltd., of Adelaide, Australia, has acquired the private biotechnology company Eclipse Therapeutics Inc., of San Diego, in a $10 million deal

Trovagene Inc., of San Diego, said it granted Quest Diagnostics Inc., of Madison, N.J., a nonexclusive license to incorporate nucleophosmin protein into research and clinical testing services related to acute myelogenous leukemia...Vical Inc., of San Diego, inked a worldwide nonexclusive license granting Bristol-Myers Squibb Co., of New York, rights to its platform DNA immunization technology and its Vaxfectin adjuvant for use in the production of antibodies

Trius Therapeutics Inc., of San Diego, reported preclinical data showing that its broad-spectrum, Gram-negative antibacterial agents directed against Gyrase B and ParE had significant potency in treating challenging Gram-negative bacteria associated with hospital-acquired infections such as E

OncoSec Medical Inc., of San Diego, secured an exclusive license for patented technology from the University of South Florida Research Foundation related to the delivery of gene-based therapeutics through intratumoral and intramuscular electroporation

to collaborate on a Phase III trial testing ASP0113 (TransVax), an investigational vaccine licensed from Vical Inc., of San Diego, for preventing cytomegalovirus (CMV) reactivations in transplant patients

Sunovion Pharmaceuticals Inc., of Marlborough, Mass., said it completed its acquisition of Elevation Pharmaceuticals Inc., of San Diego

Santarus Inc., of San Diego, said the Court of Appeals for the Federal Circuit reversed in part a lower court decision of invalidity involving certain asserted patent claims covering Zegerid (omeprazole-sodium bicarbonate) capsules and Zegerid powder for oral suspension

Cadence Pharmaceuticals Inc., of San Diego, and SCR Pharmatop SA, of France, said they received a Markman claim construction ruling in district court in their ongoing patent infringement case against Paddock Laboratories Inc., Perrigo Co., Paddock Laboratories LLC, Exela Pharma Sciences LLC, Exela Pharmsci Inc

Pure Bioscience Inc., of San Diego, finalized a previously announced reverse stock split of 1-for-8, effective at the close of the market Aug. 14...Santarus Inc., of San Diego, said the FDA has extended the PDUFA date for its ulcerative colitis drug Uceris (budesonide) tablets 9 mg to Jan. 16, 2013

MEI Pharma Inc., of San Diego, will acquire Singapore-based S*BIO Pte Ltd.'s exclusive worldwide rights to pracinostat, an oral histone deacetylase inhibitor of interest for hematologic diseases and solid tumors

Bristol-Myers Squibb Co., of Princeton, N.J., completed the tender offer for outstanding shares of common stock of Amylin Pharmaceuticals Inc., of San Diego, at $31 per share

Bristol-Myers Squibb Co. (BMS), of New York, reported the successful completion of its tender offer for all outstanding shares of Amylin Pharmaceuticals Inc., of San Diego, at $31 per share