NeuralStem plans to use the funding for its internal genomics program, which focuses on characterizing the function of genes in the central nervous system using patented CNS stem cells. • Procyon BioPharma Inc., said its PSP94 platform for prostate cancer also shows promise as a diagnostic product for the disease, according to a study to be published in the Journal of Urology

The company, formerly CytoTherapeutics Inc., focuses on the discovery and marketing of stem cell-based therapies for nervous system, liver and pancreatic diseases

stem cell cultures

Warren's research focuses on understanding the immune response that mediates graft-vs.-host disease and the graft-vs.-leukemia effect that occurs following allogeneic bone marrow or stem cell transplantation. • Gene Logic Inc., of Gaithersburg, Md., and Life Technologies Inc., of Rockville, Md., entered into a collaboration to fully sequence and patent the large number of human disease and predictive toxicology genes identified using Gene Logic's GeneExpress 2000 suite of databases

The companies will use Geron's expertise in pluripotent stem cells and Celera's sequencing and gene discovery capabilities to learn more about the function of genes involved in human cell differentiation

CD25, a T-cell activation marker that may facilitate removal of alloreactive cells (thought to be responsible for graft vs. host disease) from a stem cell graft prior to transplant...Nexell also gained the right of first refusal for potential in vivo applications of the antibodies. • Origen Therapeutics Inc., of Burlingame, Calif., and Embrex Inc., of Research Triangle Park, N.C., are combining Origen's avian embryonic stem cell technology with Embrex's in ovo technology to improve poultry

The findings are reported in the April/May issue of the Journal of Hematotherapy and Stem Cell Research. • Boston Life Sciences, of Boston, said a clinical study using Altropane to detect abnormal increases in dopamine transporter levels in the brains of selected attention deficit disorder (ADD) patients scored the highest in a peer-reviewed panel set up to judge the quality and scientific importance of papers presented at the psychiatry session of the Society of Nuclear Medicine Meeting in St

The companies signed a $100 million agreement for the product in September 1997. (See BioWorld Today, Special News Bulletin, September 9, 1997.) • ImClone Systems Inc., of New York, is collaborating with Princeton University to create a database for the identification of all genes responsible for proliferation, self-renewal and differentiation of hematopoietic stem cells

The results indicate that the engineered stem cells have replicated and differentiated within participants in the trial

MediChem issued common stock to acquire ThermoGen. • NeuroNova AB, of Stockholm, Sweden, said its scientific team at the Karolinska Institute in Stockholm has shown that stem cells in the adult mouse brain have the potential to generate a variety of cells for other organs, such as the heart, liver, muscle, intestine and other tissues...The discovery indicates that adult brain stem cells may be a valuable research tool and may potentially be used to generate cells for transplantation in the

The procedure, based on Aastrom's medium-exchange technology, improves stem cell production 10-fold compared to Aastrom's CB-I Therapy Kit, which is in a clinical trial to treat patients with leukemia and other blood diseases...The discovery could provide cancer patients with higher doses of stem cells in a transplantation setting, enhancing the probability of a successful outcome. • Alliance Pharmaceutical Corp., of San Diego, said it received $20 million as previously reported from Baxter

It will be marketed for the ex vivo selection of functional stem cells from hematopoietic tissues, such as mobilized peripheral blood. • Paradigm Genetics Inc., of Research Triangle Park, N.C., said it has exceeded the first milestone in its $55 million collaboration with Monsanto Co., of St. Louis, now known as Pharmacia Corp., in the field of functional genomics

The data are published in the May issue of the Journal of Investigative Ophthalmology and Visual Sciences. • NeuralStem BioPharmaceuticals Ltd., of College Park, Md., completed a series of agreements with Gene Logic Inc., of Gaithersburg, Md., in which Gene Logic has licensed NeuralStem's central nervous system stem cell technology for gene expression analysis and inclusion in its GeneExpress database...NeuralStem's stem cells encompass nerve cells of all the types present in the human brain at

In July 1999, Nexell received marketing clearance for its stem cell selection systems, Isolex 300 and Isolex 300i, as a means to remove tumor cells and select hematopoietic stem cells from peripheral blood used in bone marrow transplantation following aggressive chemotherapy

Ariad also said it expanded its ongoing collaboration with the university involving the development of stem cell therapy products, as well as the exclusive licensing of two of its patent applications covering methods for controlling the growth and differentiation of stem cells and other progenitor cells using ARGENT. • Pharmacia Corp., of Peapack, N.J., said the FDA approved Camptosar (irinotecan hydrochloride injection) as a first-line therapy to treat patients with metastatic colorectal

The units in the second and final closing were priced at $3.94, the stock's closing price on March 30. • StemCells California Inc., of Sunnyvale, Calif., said it has produced mature liver cells from rigorously purified blood stem cells in mice

ViaCell will leverage its cord blood banking service infrastructure and patented stem cell expansion technology to build a cellular pharmaceutical company providing products and services to treat diseases using stem cells

to deliver Athersys' synthetic microchromosome (SMC) vectors into human stem cells using Gene-Cell's automated microinjection technology...The collaboration will focus on developing and optimizing proprietary systems for the delivery of SMCs into human stem cells and other more differentiated cell types. • Avant Immunotherapeutics Inc., of Needham, Mass., said its Phase I/II study of TP10 met its objectives in infants undergoing cardiac surgery

Hepatocyte precursors, a subpopulation of cells that include liver stem cells and other liver progenitors, are capable of extensive growth and of maturing into the functioning liver tissue