Onyx Pharmaceuticals Inc., of South San Francisco, said the FDA accepted the new drug application (NDA) for carfilzomib, a next-generation proteasome inhibitor, for relapsed and refractory multiple myeloma

Galena Biopharma Inc., of Lake Oswego, Ore., entered a clinical development collaboration with Genentech Inc., of South San Francisco, and the Henry M. Jackson Foundation for the Advancement of Military Medicine to develop NeuVax (E75) in combination with Genentech's Herceptin (trastuzumab) in adjuvant breast cancer patients currently not eligible for Herceptin therapy

Genmab A/S, of Copenhagen, Denmark, said a U.S. District Court entered final judgment in favor of GlaxoSmithKline plc, of London, in a patent infringement case involving Arzerra (ofatumumab) brought against GSK by South San Francisco-based Genentech Inc. (now part of Roche AG) and Weston, Mass.-based Biogen Idec Inc

Poniard Pharmaceuticals Inc., of San Francisco, reported that its shareholders have approved proposals to complete the previously announced merger with Allozyne Inc., of Seattle

Poniard Pharmaceuticals Inc., of San Francisco, said it licensed worldwide rights to an undisclosed party to its focal adhesion kinase (FAK) technology, including a preclinical small-molecule FAK inhibitor candidate

Genmab A/S, of Copenhagen, Denmark, said a U.S. District Court entered final judgment in favor of GlaxoSmithKline plc, of London, in a patent infringement case involving Arzerra (ofatumumab) brought against GSK by South San Francisco-based Genentech Inc. (now part of Roche AG) and Weston, Mass.-based Biogen Idec Inc...VistaGen Therapeutics Inc., of South San Francisco, and the University Health Network (UHN), a Canadian research hospital, expanded their existing collaborative pluripotent stem cell

Titan Pharmaceuticals Inc., of South San Francisco, said it agreed to sell a substantial portion of its remaining future royalties on the sales of Fanapt (iloperidone), an atypical antipsychotic approved for schizophrenia in adults and marketed by Basel, Switzerland-based Novartis AG, to Deerfield Management Co

Napo Pharmaceuticals Inc., of San Francisco, terminated its 3-year-old collaboration with Salix Pharmaceuticals Inc., of Raleigh, N.C., to develop crofelemer, a diarrhea treatment

Curis Inc., of Lexington, Mass., and Genentech Inc., of South San Francisco, a member of the Roche Group, said the FDA accepted and filed the new drug application (NDA) for vismodegib, a Hedgehog pathway inhibitor, for use in adults with advanced basal cell carcinoma (BCC) for whom surgery is considered inappropriate

Alios BioPharma Inc., of South San Francisco, and Versitech Ltd., of Hong Kong, signed an exclusive worldwide licensing agreement for technology to advance the research, development, manufacture and commercialization of medicines to treat influenza virus

Poniard Pharmaceuticals Inc., of San Francisco, said Egan-Jones Proxy Services, an independent proxy advisory firm, has recommended that Poniard shareholders vote for proposals related to the issuance of stock in connection with the company's proposed merger with Allozyne Inc., of Seattle, and a 1-for-40 reverse stock split

Following a pre-new drug application (NDA) meeting with the FDA Tuesday, Titan Pharmaceuticals Inc., of South San Francisco, said no additional efficacy or safety studies will be required to support the submission of an NDA for Probuphine (buprenorphine) via the 505(b)(2) pathway

Cytokinetics Inc., of South San Francisco, said it will restructure its work force and operations to focus resources primarily on the development of its later-stage development programs, CK-2017357 for amyotrophic lateral sclerosis and omecamtiv mecarbil, a cardiac muscle compound partnered with Amgen Inc., of Thousand Oaks, Calif

The National Institutes of Health awarded the University of California San Francisco $718, 136 in funding to discover and optimize oxaborales as antimalarial drug candidates

Cytokinetics Inc., of South San Francisco, published preclinical data showing CK-2018488, a small-molecule direct inhibitor of smooth muscle myosin, significantly increased renal blood flow compared to the calcium channel blocker amlodipine in a canine model of hypertension

VistaGen Therapeutics Inc., of South San Francisco, published preclinical data showing that pluripotent stem cells can be used to generate insulin in mice

KAI Pharmaceuticals Inc., of South San Francisco, said it inked a regional partnership with Ono Pharmaceutical Co...Theravance Inc., of South San Francisco, and partner Astellas Pharma Inc., of Tokyo, received European approval of antibiotic Vibativ (telavancin) for nosocomial pneumonia, including ventilator-associated pneumonia, known or suspected to be caused by MRSA when other alternatives are not suitable

A Nasdaq panel said Poniard Pharmaceuticals Inc., of San Francisco, may continue to list its stock on Nasdaq, provided it meets certain conditions by Dec. 31

Titan Pharmaceuticals Inc., of South San Francisco, said the FDA confirmed an Oct. 25 pre-new drug application meeting regarding Probuphine, a subcutaneous implant formulation designed to deliver round-the-clock dosing of buprenorphine over six months following a single treatment for use in opioid dependence