Althea Technologies Inc., of San Diego, named Rick Hancock president and CEO, Chris Duffy senior vice president of operations and E.J. Brandreth senior vice president of quality and regulatory...SpringLeaf Therapeutics Inc., of Boston, appointed Pieter Muntendam president and CEO...Ventrus Biosciences Inc., of New York, appointed JP Benya vice president, commercial operations and business development

Named Howard Rosen vice president, sales and marketing, and Thomas Bendix Mortensen vice president, sales and marketing in Europe...Circassia Ltd., of Oxford, UK, appointed Brett Haumann chief medical officer and Stewart Sharpe vice president, commercial operations

he will chair the audit committee and serve on the compensation committee...Cangene Corp., of Winnipeg, Manitoba, appointed Michael Adelman vice president, commercial operations

Mark Oki senior vice president, finance and chief financial officer...Mike Keavany vice president of commercial operations, North America

Paratek Pharmaceuticals Inc., of Boston, appointed Dennis Molnar CEO and director and Evan Loh chief medical officer and board chairman...Talon Therapeutics Inc., of San Mateo, Calif., appointed Thomas DeZao head of commercial operations and planning functions

Trovagene Inc., of San Diego, appointed Keith McCormick head of commercial operations...XOMA Corp., of Berkeley, Calif., named Paul Rubin senior vice president, research and development

CombiMatrix Corp., of Irvine, Calif., appointed Richard Ding and Joseph Limber to its board...and Christine Mikail, executive vice president, corporate development, general counsel and secretary

Accera Inc., of Broomfield, Colo., appointed Holger Kunze CEO and board member...BioTime Inc., of Alameda, Calif., and its subsidiary, OncoCyte Corp., each appointed Andrew von Eschenbach to their boards...CBio Ltd., of Brisbane, Australia, named Ralph Craven chairman and appointed Helen Cameron interim managing director

It also named Gerald Commissiong president and CEO and appointed Owen Garrick strategic advisor to its board...Amgen Inc., of Thousand Oaks, Calif., appointed Anthony (Tony) Hooper executive vice president of global commercial operations and named Robert A. Bradway to its board

Plethora Solutions Holdings plc, of London, appointed Richard Horsman to its board and named Billy Hargan vice president of commercial operations...Protox Therapeutics Inc., of Vancouver, British Columbia, named William Rohn and Arnit Sobti to its board

Gentium SpA, of Villa Guardia, Italy, appointed Adrian Haigh senior vice president of commercial operations...Otonomy Inc., of San Diego, appointed G. Michael Wall vice president of product development and named Cindy Berejikian vice president of program management

Markus Leyck Dieken senior vice president and general manager, Germany...and Manuela Maronati vice president, sales and marketing, Europe

Topaz Pharmaceuticals Inc., of Horsham, Pa., appointed Bob Radie president and CEO...Unigene Laboratories Inc., of Boonton, N.J., appointed Alex Martin vice president of business development and head of commercial operations

OncoMethylome Sciences SA, of Durham, N.C., appointed Melissa A. Thompson vice president of regulatory affairs and quality assurance and named Christopher (Chris) Thibodeau vice president of commercial operations...Regenicin Inc., of New York, added Joseph Rubinfeld and Craig Eagle to its board

BioMarin Pharmaceutical Inc., of Novato, Calif., appointed William D. Young and Kenneth M. Bate to its board...Corcept Therapeutics Inc., of Menlo Park, Calif., appointed Steven Lo vice president of commercial operations

Celsion Corp., of Columbia, Md., appointed Sid Taubenfeld director of communications and strategic initiatives and named Robert W. Hooper to its board...MedImmune Inc., of Gaithersburg, Md., named Scott Carmer executive vice president of commercial operations

Probiodrug AG, of Halle, Germany, appointed Claus Braestrup chairman and named Lennart Mucke to its scientific advisory board...Spencer Pharmaceutical Inc., of Boston, named Max Arella president and chairman...YM BioSciences Inc., of Mississauga, Ontario, appointed Nick Glover president and chief operating officer

Ablexis LLC, of San Francisco, appointed Scott Greer chairman and named Richard Hoffman chief business officer...Bioheart Inc., of Sunrise, Fla., appointed Mike Tomas president, CEO and board member, replacing Karl Groth, who will retain his position as chairman...Jennerex Inc., of San Francisco, appointed Gregory W. Schafer senior vice president and chief financial officer

He formerly was vice president of regulatory affairs and clinical research at Mystic Pharmaceuticals Inc...and served as senior consultant at Parexel International Corp...The company also named Sam Backenroth interim chief financial officer and vice president of business development