Generex Biotechnology Corp., of Worcester, Mass., added Keith Knutson and James Mule to its scientific advisory board...PolyTherics Ltd., of London, added Anker Lundemose and Nigel Pitchford to its board...Promedior Inc., of Malvern, Pa., appointed Suzanne Bruhn president and CEO

Galena Biopharma Inc., of Lake Oswego, Ore., named Rosemary Mazanet executive vice president and chief medical officer and appointed Robert Figlin to its scientific advisory board...Incline Therapeutics Inc., of Redwood City, Calif, named John Tucker senior vice president and chief commercial officer

AMAG Pharmaceuticals Inc., of Lexington, Mass., appointed William Heiden president and CEO...Blueprint Medicines, of Cambridge, Mass., named George Demetri clinical advisor and member of the scientific advisory board...Cynapsus Therapeutics Inc., of Toronto, nominated Perry Molinoff, Thomas Picone and President and CEO Anthony Giovinazzo to its board

Biodel Inc., of Danbury, Conn., added Julia Brown and Davey Scoon to its board...Knopp Biosciences, of Pittsburgh, named Steven Boyd senior director of chemistry and Ian Reynolds senior director of biology...Sernova Corp., of London, Ontario, elected Bruce Weber and James Parsons to its board

XOMA Corp., of Berkeley, Calif., named Paul Rubin senior vice president, research and development

China Biologic Products Inc., of Beijing, added Zhijun Tong and Sandy (Han) Zhang to its board...Kolltan Pharmaceuticals Inc., of New Haven Conn., named Gerald McMahon president and CEO...Sorbent Therapeutics, of Sunnyvale, Calif., appointed Howard Dittrich chief medical officer and Randall Woods board chairman

and Santosh Varghese vice president of medical affairs...The company promoted Barbara Troupin to vice president, scientific communication and risk management...named CFO Timothy Morris senior vice president, global corporate development and finance

LLC, of Kalamozoo, Mich., added Barbara Cannon to its science and medical advisory board...Northwest Biotherapeutics, of Bethesda, Md., added Navid Malik and Jerry Jasinowski to its board...Syndax Pharmaceuticals Inc., of Waltham, Mass., appointed Arlene Morris CEO and Joanna Horobin president

AcelRx Pharmaceuticals Inc., of Redwood City, Calif., named Kim Gaumer vice president, regulatory affairs and quality assurance...Array BioPharma Inc., of Boulder, Colo., appointed Howard Holden vice president of regulatory affairs and quality assurance...Avion Pharmaceuticals LLC, of Atlanta, appointed Michael Sullivan vice president, sales and marketing

Adventrx Pharmaceuticals Inc., of San Diego, formed a regulatory advisory board (RAB) and appointed Cindy Dinella and Bonnie Hepburn to the RAB, with Frank Sasinowski as RAB advisor...InDex Pharmaceuticals AB, of Stockholm, Sweden, appointed Pernilla Sandwall head of clinical operations and Thomas Knittel chief medical officer

Pluristem Therapeutics Inc., of Haifa, Israel, appointed Jeffrey Olin, Manesh Patel, Petra Reinke and J. Andre Schmidt-lucke to its new peripheral artery disease steering committee...PTC Therapeutics Inc., of South Plainfield, N.J., named Claudia Hirawat president and Mark Boulding executive vice president and chief legal officer

Constellation Pharmaceuticals Inc., of Cambridge, Mass., named Keith Dionne president and CEO and Mark Goldsmith executive chairman of the board...Intermune Inc., of Brisbane, Calif., added Jean-Jacques Bienaime and Frank Verwiel to its board...OvaScience, of Cambridge, Mass., added Jeffrey Capello and John Simon to its board

3SBio Inc., of Shenyang, China, named Jing Lou board chairman and added Dongmei Su to its board...Anaphore Inc., of La Jolla, Calif., added Peppi Prasit and Raymond Stevens to its board...Silence Therapeutics plc, of London, appointed Detlef Schuppan and Massimo Pinzani to its newly created scientific advisory board

CombiMatrix Corp., of Irvine, Calif., appointed Richard Ding and Joseph Limber to its board...and Christine Mikail, executive vice president, corporate development, general counsel and secretary

Sirona also appointed Sean Cunliffe chief business officer and board member...Trovagene Inc., of San Diego, named Charlie Rodi vice president and chief technology officer...ValiRx plc, of London, named Hilary Calvert, Richard Harbottle and Jean-Frederic Sauniere to its scientific advisory board

ImmunoGen Inc., of Waltham, Mass., added Kristine Peterson and Dean Mitchell to its board...and added Eunan Maguire senior vice president of strategy and corporate development

Acella Pharmaceuticals Inc., of Atlanta, appointed Allen Fields vice president and head of R&D...Adeona Pharmaceuticals Inc., of Ann Arbor, Mich., appointed Jeff Riley president and CEO, added C. Evan Ballantyne as chief financial officer and named Scott L. Tarriff and Nelson K. Stacks to the board...AMAG Pharmaceuticals Inc., of Lexington, Mass., appointed Rajiv De Silva and Gino Santini to its board

The revisions will reflect technological advancements and marketing developments that have emerged over the past decade...Viewed as a way to take the hard choices of curbing Medicare expenses out of the hands of Congress, the board – made up of presidential appointments confirmed by the Senate – is charged with cutting Medicare costs if its spending exceeds a predetermined target growth rate. (See BioWorld Today, July 14, 2011, and Sept. 20, 2011.) Although President Barack Obama has proposed

It also added John E. Dick and Janet Rossant to its scientific and clinical advisory board...Zealand Pharma A/S, of Copenhagen, Denmark, named Alain Munoz and Christian Grøndahl joint chairs to its new clinical and scientific advisory board