APPOINTMENTS AND ADVANCEMENTS * Alizyme Ltd., of London, appointed Brian Richards as non- executive chairman and Stewart Siddall and Alan Goodman as non- executive directors. * Applied Imaging Corp., of Santa Clara, Calif., said G. Kirk Raab joined the board of directors

and corporate treasurer. * Nextran, of Princeton, N.J., named Ramesh Kumar senior director of business development. * Carrington Laboratories Inc., of Irving, Texas, appointed David Shand executive vice president of research and development. * Pharmacopeia Inc., of Princeton, N.J., named Lewis Shuster chief financial officer. * Trimeris Inc., of Durham, N.C., appointed M. Ross Johnson chief scientific officer and vice president of research and development. * Repligen Corp., of Cambridge

Dalby will serve as non-executive chairman of the board until his planned retirement in May 1994...Turner was president and chief executive officer of Princeton Diagnostic Laboratories of America...Anthony Nicholls, president and chief executive officer of Trinity Biotech of Dublin, Ireland, has been elected chairman of the board, replacing Denis Burger, who is retiring as chairman