and Boston, appointed Claude Benedict senior vice president, clinical development and regulatory affairs

Molecular Insight Pharmaceuticals Inc., Cambridge, Mass., appointed Norman LaFrance senior vice president, clinical development and chief medical officer...Neuralstem Inc., of Rockville, Md., appointed Scott Ogilvie and William Oldaker to its board...Craig Ritchie to chief European clinical adviser, and Robert Cherny to head of research

Kythera Biopharmaceuticals Inc., of Los Angeles, appointed Patricia Walker chief medical officer and vice president, clinical development and regulatory affairs

Avigen Inc., of Alameda, Calif., said Stephen Dilly and Jan Ohrstrom were elected to its board...Eurand, of Milan, Italy, appointed Manya Deehr chief legal officer and general counsel...Also, Bill Radvak, president and CEO, intends to step down after a replacement is found

Santhera Pharmaceuticals, of Liestal, Switzerland, appointed MJ Roach vice president of marketing and sales...Symphogen, of Copenhagen, Denmark, said Christian Meyer was appointed vice president of clinical development

Christine Dingivan senior vice president of clinical development and operations...and Alan Taggart vice president of government project management

Digene Corp., of Gaithersburg, Md., named Daryl Faulkner president and CEO and a board member...Kosan Biosciences Inc., of Hayward, Calif., named Robert De Jager senior vice president of clinical development and chief medical officer

Akesis Pharmaceuticals Inc., of San Diego, named Jay Lichter president and CEO...enGene Inc., of Vancouver, British Columbia, appointed Christopher Rhodes and Imre Kovesdi scientific advisers...IntegraGen SA, of Paris, named Emmanuel Martin director of sales and marketing for its new genetic research service business unit

Lorus Therapeutics Inc., of Toronto, named Aiping Young as president and CEO, and appointed Georg Ludwig and Michael Moore to its board...Ltd., of Singapore, appointed Klaus Brandau, Clemens Doppler and Harald Labischinski to its board

Adventrx Pharmaceuticals Inc., of San Diego, appointed president and CEO Jack Lief to the board...BioTrove Inc., of Woburn, Mass., appointed Albert Luderer as president, CEO and board member, and appointed Edward Erickson to the board

and Margaret Wasilewski vice president, clinical development and medical science team leader

and Margaret Wasilewski vice president, clinical development and medical science team leader

Pharmacyclics Inc., of Sunnyvale, Calif., appointed James Knighton and Christine White to its board...It also established a business advisory board and appointed three former company directors to it: William Milligan, Andrew Saxton and Christopher Neuman

LifeCycle Pharma A/S, of Horsholm, Denmark, appointed Flemming Ornskov president and CEO...Medicure Inc., of Winnipeg, Manitoba, appointed Jan-Ake Westin vice president of clinical development...Osiris Therapeutics Inc., of Baltimore, appointed Jay Moyes and Gregory Barnhill to its board

Pharmacyclics Inc., of Sunnyvale, Calif., appointed James Knighton and Christine White to its board...It also established a business advisory board and appointed three former company directors to it: William Milligan, Andrew Saxton and Christopher Neuman

Solvay Pharmaceuticals Inc., of Marietta, Ga., said its president and CEO, Laurence Downey, was named to the board of the Pharmaceutical Research and Manufacturers of America...Vical Inc., of San Diego, appointed Ronald Moss vice president, clinical development

and Michael Palfreyman vice president, program management and drug development...iCo Therapeutics, of Vancouver, British Columbia, appointed Richard Barker and William Jarosz to its board, and Philip Rosenfeld to its strategic advisory team

Celldex Therapeutics Inc., of Phillipsburg, N.J., appointed Thomas Davis chief medical officer and vice president of clinical development, and Tibor Keler chief scientific officer and vice president of research and development

and David Schenkein vice president, clinical hematology and oncology...and William Kelly vice president, investor relations and corporate communications