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Pfizer Phase III Failure Hints at ADC Shortcomings
New York-based Pfizer said it would discontinue development of the drug in NHL after an independent data monitoring committee concluded during a scheduled interim analysis that the treatment would not meet the primary endpoint of improving overall survival compared with investigator's choice of bendamustine plus rituximab or gemcitabine plus rituximabBy Marie Powers | BioWorld Today | Wednesday, May 22, 2013 -
Novo Snags Xellia for $700M; Continues Investment Strategy
The company was formed in 2008 through a management buyout of the active pharmaceutical ingredients business of Alpharma Inc. (now part of New York-based Pfizer IncBy Cormac Sheridan | BioWorld Today | Wednesday, May 22, 2013 -
Novo Snags Xellia for $700M; Continues Investment Strategy
The company was formed in 2008 through a management buyout of the active pharmaceutical ingredients business of Alpharma Inc. (now part of New York-based Pfizer IncBy Cormac Sheridan | BioWorld International | Wednesday, May 22, 2013 -
Elan Looks East with 2 Deals as Royalty Revises Hostile Bid
A couple of hours later, it edged up further after New York-based Royalty Pharma upped its bid for the companyBy Cormac Sheridan | BioWorld International | Wednesday, May 22, 2013 -
Not 'Growthy,' Tax-Wise Deal: Actavis Takes Warner Chilcott
Most of Actavis' sales, at this point, derive from generic therapies, including major revenue generators such as those for New York-based Pfizer Inc.'s cholesterol-buster Lipitor (atorvastatin), and for Concerta (methylphenidate hydrochloride), the compound for attention-deficit and hyperactivity disorder from Johnson & Johnson, of New Brunswick, N.JBy Randy Osborne | BioWorld Today | Tuesday, May 21, 2013 -
Clinic Roundup
Intercept Pharmaceuticals Inc., of New York, reported initial results from OBADIAH, an ongoing Phase IIa trial of obeticholic acid (OCA) as a treatment for primary bile acid diarrhea (PBAD), showing that treatment with OCA is associated with statistically significant increased levels of fibroblast growth factor 19 (FGF19) and improvement in clinical symptoms in patients with PBADBioWorld Today | Tuesday, May 21, 2013 -
Elan Looks East with 2 Deals as Royalty Revises Hostile Bid
A couple of hours later, it edged up further after New York-based Royalty Pharma upped its bid for the companyBy Cormac Sheridan | BioWorld Today | Tuesday, May 21, 2013 -
Other News To Note
Relmada Therapeutics Inc., of New York, retained Brio Financial Group and GBH CPAs PC as financial reporting consultant and audit firms, respectively, to prepare for a public listingBioWorld Today | Tuesday, May 21, 2013 -
Biotech Collaborations Between Pharmaceutical & Miscellaneous Companies: April 1 - May 16, 2013
Inc. (Whitehouse Station, N.J.) Bristol-Myers Squibb Co. (New York) ND Nonexclusive deal to conduct a Phase II trial of a once-daily oral combination regimen consisting of BMS' NS5A replication complex inhibitor daclatasvir and Merck's NS3/4A protease inhibitor MK-5172 to treat chronic hepatitis C virus Merck will conduct the trial 4/23/13 Merck KGgA (Darmstadt, Germany) Pfizer Inc. (New York) ND Extended collaboration signed in 2002 by Merck's subsidiary EMD Serono Inc...Inc. (Whitehouse StationBioWorld Insight | Monday, May 20, 2013 -
Collaborations Between Biotech And Pharmaceutical Companies: April 1 - May 16, 2013
it also gets research funding and royalties, while BMS holds onto worldwide rights 4/17/13 Tetragenetics Inc. (Cambridge, Mass.) Pfizer Inc. (New York) ND Deal with an option for an exclusive license with Pfizer using Tetragenetics' SionX application of its discovery platform Financial terms were not disclosed 4/4/13 X-BODY Biosciences Inc. (Waltham, Mass.) Jiangsu Hengrui Medicine Co...Merck gains worldwide commercialization rights and will pay royalties to Abide 5/3/13 Adaptive BiotechnologiesBioWorld Insight | Monday, May 20, 2013 -
As Markets Fancy Biotech, PTC Therapeutics Joins IPO Queue
In 2007, the company inked a blockbuster deal with Pfizer Inc., of New York, focused on its Gene Expression Modulation by Small-molecules (GEMS) technology platform, which identifies small molecules that regulate post-transcriptional control mechanismsBy Marie Powers | BioWorld Today | Monday, May 20, 2013 -
Pharma: Other News To Note
Bristol-Myers Squibb Co., of New York, said it has notified the New York Stock Exchange (NYSE) of its intention to voluntarily delist its $2 convertible preferred stock from the NYSE, a decision driven by the low number of shares outstanding, low daily trading volume, listing fees and compliance administration costsBioWorld Today | Monday, May 20, 2013 -
Appointments and Advancements
Intra-Cellular Therapies Inc., of New York, added Michael Rawlins to its board...Ohr Pharmaceutical Inc., of New York, added Thomas M. Riedhammer to its boardBioWorld Today | Monday, May 20, 2013 -
Other News To Note
In 2011, Clovis paid an undisclosed up-front fee to Pfizer Inc., of New York, plus potential milestones of $255 million, in exchange for the right to develop and commercialize the oral Poly(ADP-ribose) polymerase, or PARP, inhibitor, then in Phase I studiesBioWorld International | Wednesday, May 15, 2013 -
Elan Buying into Theravance, GSK Royalty Stream for $1B
That position, taken together with this latest deal, points to a possible future for the company as a royalty management outfit – akin to that of its would-be acquirer, the New York-based Paul Royalty Fund – but this is not the only path it intends to pursueBy Cormac Sheridan | BioWorld International | Wednesday, May 15, 2013 -
Elan Buying into Theravance, GSK Royalty Stream for $1B
That position, taken together with this latest deal, points to a possible future for the company as a royalty management outfit – akin to that of its would-be acquirer, the New York-based Paul Royalty Fund – but this is not the only path it intends to pursueBy Cormac Sheridan | BioWorld Today | Tuesday, May 14, 2013 -
Other News To Note
The Nasdaq OMX Group Inc., of New York, reported the semi-annual re-ranking of the Nasdaq Biotechnology Index, which will become effective prior to the market's open on May 20BioWorld Today | Tuesday, May 14, 2013 -
Clinic Roundup
In 2011, Clovis paid an undisclosed up-front fee to Pfizer Inc., of New York, plus potential milestones of $255 million, in exchange for the right to develop and commercialize the oral Poly(ADP-ribose) polymerase, or PARP, inhibitor, then in Phase I studiesBioWorld Today | Monday, May 13, 2013 -
Phase II Clinical Trials Update: April 2013
Company (Location) Product Description Indication Status Date AUTOIMMUNE Biogen Idec Inc. (Weston, Mass.) DAC HYP A daclizumab high-yield process Multiple sclerosis Phase IIb data showed it reduced the annualized relapsed rate by 54%, meeting the study's primary endpoint 4/5/13 Fibrocell Science Inc. (Exton, Pa.) LaViv Autologous fibroblast injection azficel-T Moderate-to-severe acne scars Phase II study demonstrated that azficel-T treatment was associated with clinically meaningful improvementBioWorld Insight | Monday, May 13, 2013 -
Pharma Clinical & FDA Action Update: April 2013
Company (Location) Product Description Indication Status Date Actavis Inc. (Parsippany, N.J.) Testosterone Gel 1.62%, a generic version of AbbVie Inc.'s AndroGel 1.62% Absence of endogenous testosterone Filed an abbreviated NDA with the FDA 4/2/13 Almirall SA (Barcelona, Spain) and Forest Laboratories Inc. (New York) Aclidinium bromide and formoterol fumarate A long-acting muscarinic beta2 agonist and a long-acting beta2 agonist Chronic obstructive pulmonary disorder Top-line Phase III dataBioWorld Insight | Monday, May 13, 2013
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