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Ltd., said Harvard Medical School presented data at the Association for Research in Vision and Ophthalmology conference in Seattle showing a major link between vascular endothelial growth factor (VEGF)-C levels and age-related macular degeneration (AMD) and that assessment of Opthea's drug development candidate, VGX-300 (a soluble form of VEGF receptor-3 that blocks VEGF-C and VEGF-D) in animal models of wet AMD confirmed its potential as a new therapy for the diseaseBioWorld International | Wednesday, May 15, 2013 -
Clinic Roundup
Ltd., said Harvard Medical School presented data at the Association for Research in Vision and Ophthalmology conference in Seattle showing a major link between vascular endothelial growth factor (VEGF)-C levels and age-related macular degeneration (AMD) and that assessment of Opthea's drug development candidate, VGX-300 (a soluble form of VEGF receptor-3 that blocks VEGF-C and VEGF-D) in animal models of wet AMD confirmed its potential as a new therapy for the diseaseBioWorld Today | Friday, May 10, 2013 -
ODAC Takes AVEO to Task over Single Phase III Trial
Not one "to let the perfect be the enemy of the good," David Steensma, an associate professor at Harvard Medical School, said all trials are flawedBy Mari Serebrov | BioWorld Today | Friday, May 3, 2013 -
Bench Press: BioWorld Looks at Translational Medicine
Kinase Has 2 Distinct Roles in Inflammation Researchers from Harvard Medical School have discovered a compound that can be used to gain new insights into how the inflammasome is activatedBioWorld Today | Monday, April 29, 2013 -
New Partnerships Sought to Innovate Drug Development
Despite his training at Harvard Medical School and Merck & CoBy Marie Powers | BioWorld Today | Thursday, April 25, 2013 -
BIND's Accurin Platform Lands $200M AstraZeneca Partnership
BIND, which was founded in 2007 based in work by MIT professor Robert Langer and Harvard Medical School assistant professor Omid Farokhzad, has raised nearly $90 million in venture fundingBy Jennifer Boggs | BioWorld International | Wednesday, April 24, 2013 -
BIND's Accurin Platform Lands $200M AstraZeneca Partnership
BIND, which was founded in 2007 based in work by MIT professor Robert Langer and Harvard Medical School assistant professor Omid Farokhzad, has raised nearly $90 million in venture fundingBy Jennifer Boggs | BioWorld Today | Tuesday, April 23, 2013 -
Women Leaders in Biotech: 'Walls Are Coming Down'
Williams, however, decided to expand her knowledge and responsibilities and moved toward medical school, stopping along the way to work with physicians on research sponsored by GlaxoSmithKline plcBy Catherine Shaffer | BioWorld Today | Wednesday, April 17, 2013 -
Pfizer 'BINDS' to Accurins in Potential $210M-Plus Deal
In addition to the economics, BIND's ability to attract a second major partner to its medicinal nanoengineering platform represents solid validation for the biotech, launched in 2006 by prolific scientists and entrepreneurs Robert Langer, of the Massachusetts Institute of Technology, and Omid Farokhzad, of Harvard Medical SchoolBy Marie Powers | BioWorld Today | Thursday, April 4, 2013 -
Antibodies to Self: Have Complex Relationship with Autoimmunity
His parody of what he learned about the autoinflammatory disease gout in medical school was that it results when "uric acid crystals make neutrophils angryBy Anette Breindl | BioWorld Today | Monday, March 25, 2013 -
Nanoparticles to Speed Up the End of Inflammation
The researchers have experience in commercializing research findings – the Massachusetts Institute of Technology's Robert Langer, who is a co-corresponding author, has founded literally dozens of companies, and is an inventor on a patent estate that puts many nanotechnology companies to shame. (See BioWorld Insight, March 4, 2013.) Omid Farokhzad, of Harvard Medical School, is another co-author who has experience in bringing science to market, as the co-founder of three companies: BINDBy Anette Breindl | BioWorld Today | Tuesday, March 19, 2013 -
Multiple Strategies Employed To Build Early Stage Pipelines
Academic Partnership Pfizer Inc established Centers for Therapeutic Innovation (CTI) in academic institutions, typically medical schools although Sanford-Burnham Medical Research Institute is one of the sitesBy Brian Orelli | BioWorld Insight | Monday, March 18, 2013 -
Sirtuin Research Fuels (Anti-) Age Old Debate
Sinclair is at Harvard Medical School and the senior author of the new findings, which were published in the March 8, 2013, issue of ScienceBy Anette Breindl | BioWorld Insight | Monday, March 18, 2013 -
GSK Closing Sirtris Lab, Moving Research In-House
Sirtris was co-founded by David Sinclair of Harvard Medical School, Christoph Westphal, then a general partner at Polaris Venture Partners and the start-up's CEO, and Greatpoint VenturesBy Marie Powers | BioWorld Today | Thursday, March 14, 2013 -
$0.00Audio Conferences | Tuesday, March 12, 2013
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In AIDS Cure Case, the Question of Just How Infected is Infected
Testing the mother after she had given birth (a birth which occurred too rapidly for test results to be available before it was all over) revealed that she was HIV-positive, and the baby was transferred to the University of Mississippi Medical School, tested with two separate blood draws, determined to be HIV positive, and put on antiretroviral drugs within the first 31 hours of its lifeBy Anette Breindl | BioWorld Insight | Monday, March 11, 2013 -
Bench Press: BioWorld Looks at Translational Medicine
Salt Linked to Autoimmune-Prone Cells Three separate papers, by scientists from the Broad Institute, Harvard Medical School and Yale Medical School have identified salt as a culprit in the development of autoimmune diseaseBioWorld Today | Monday, March 11, 2013 -
Companies Look to Capture Part of Growing Respiratory Market
A team from Brigham and Women's Hospital and Harvard Medical School has implicated activated innate lymphoid cells in the damage caused by asthma, and identified the molecule lipoxin A as a signal that naturally dampens the activity of those cells and so might be a therapeutic target in asthmaBy Peter Winter | BioWorld Insight | Monday, March 11, 2013 -
Panel Gives Thumbs-Down to Depomed's Hot Flash Drug
However, the risk cannot be ignored for a treatment with marginal effectiveness," said Chair Julia Johnson, professor and chair of the department of obstetrics and gynecology and the University of Massachusetts Medical SchoolBy Jennifer Boggs | BioWorld Today | Tuesday, March 5, 2013 -
Bench Press: BioWorld Looks at Translational Medicine
Reining in Innate Immunity in Asthma A team from Brigham and Women's Hospital and Harvard Medical School has implicated activated innate lymphoid cells in the damage caused by asthma, and identified the molecule lipoxin A as a signal that naturally dampens the activity of those cells and so might be a therapeutic target in asthmaBioWorld Today | Monday, March 4, 2013
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