Neoprobe Corp., of Dublin, Ohio, appointed Mark Pykett president and CEO...Regulus Therapeutics Inc., of La Jolla, Calif., named Lars Karlsson vice president of immunology and fibrosis...Tobira Therapeutics Inc., of Manalapan, N.J., named Andrew Hindman president and CEO

Concert Pharmaceuticals Inc., of Lexington, Mass., appointed Mark Roessel vice president of regulatory affairs and quality assurance and named LuAnn Sabounjian vice president of clinical operations...Infinity Pharmaceuticals Inc., of Cambridge, Mass., appointed Joshua D. Hamermesh vice president of business and corporate development...Lightlake Therapeutics Inc., of London, appointed Cynthia McCormick as senior clinical and regulatory advisor

KaloBios Pharmaceuticals Inc., of South San Francisco, added Jonathan Leff as chief medical officer and named Gary A. Lyons to its board...Labopharm Inc., of Laval, Quebec, elected Mark D'Souza president, CEO and board member...Pro-Pharmaceuticals Inc., of Newton, Mass., named Peter G. Traber president and CEO

Hospira Inc., of Lake Forest, Ill., elected F. Michael (Mike) Ball CEO and board member...ITherX Pharmaceuticals Inc., of San Diego, named Stefan Zeuzem chairman of its scientific and clinical advisory board

Pearl Therapeutics Inc., of Redwood City, Calif., appointed Chuck Bramlage president and CEO...Plethora Solutions Holdings plc, of London, appointed Richard Horsman to its board and named Billy Hargan vice president of commercial operations...Protox Therapeutics Inc., of Vancouver, British Columbia, named William Rohn and Arnit Sobti to its board

ATyr Pharma, of San Diego, formed a therapeutic advisory board comprising Thomas O. Daniel, L. Patrick Gage, Rich Heyman, Keith James, Paul Negulescu, Timothy Rink, Wendell Wierenga and Doug Williams...Otonomy Inc., of San Diego, appointed G. Michael Wall vice president of product development and named Cindy Berejikian vice president of program management

executive vice president and chief operating officer and named John A. Bellano senior vice president of sales and commercial programs

Markus Leyck Dieken senior vice president and general manager, Germany...and Manuela Maronati vice president, sales and marketing, Europe

Receptos Inc., of San Diego, appointed Faheem Hasnain president, CEO and board member...Selvita, of Krakow Poland, appointed Piotr Prelich vice president of sales and marketing...Topaz Pharmaceuticals Inc., of Horsham, Pa., appointed Bob Radie president and CEO

OctoPlus NV, of Leiden, the Netherlands, named Jan Hendrik Egberts and nominated him for appointment as CEO...Optimer Pharmaceuticals Inc., of San Diego, named Kurt Hartman general counsel and access...Protox Therapeutics Inc., of Vancouver, British Columbia, named Lars Ekman chairman and added Jonathan Leff and Nishan de Silva to the board

and added Tamara A. Seymour as chief financial officer...Hybrigenics, of Paris, named William Vickery head of corporate and business development...Medistem Inc., of San Diego, appointed Vladimir Bogin president and chairman

Celtaxys Inc., of Atlanta, named Michael Hanley CEO and chairman...Codexis Inc., Redwood City, Calif., named William Rothwell vice president and general manager of Biobased Chemicals...Cytomedix Inc., of Gaithersburg, Md., formed a scientific advisory board with the appointments of Marissa Carter, Jean de Leon, Vickie R. Driver, Peter A. M. Everts, Will W. Li and Thomas E. Serena

plc, of Dublin, Ireland, appointed Kristine Peterson to its board and named Joseph S. Zakrzewski CEO...Ambit Biosciences Corp., of San Diego, named Faheem Hasnain chairman and appointed Alan Fuhrman chief financial officer...AnaptysBio Inc., of San Diego, named Jan de Vries, Nicholas B. Lydon and Phillip A. Patten to its scientific and therapeutic advisory boards

Roche, of Nutley, N.J., named Jacques Banchereau senior vice president and head of the inflammation and virology discovery and translational areas

Cytogenix Inc., of New York, appointed Kevin Cassidy and Campbell Murray to its board...Generex Biotechnology Corp., of Worcester, Mass., appointed Mark Fletcher interim president and CEO and named John P. Barratt chairman

Accera Inc., of Broomfield, Colo., appointed Thomas Werner president and CEO...Agile Therapeutics Inc., of Princeton, N.J., named Al Altomari president and CEO...AIKO Biotechnology, of Portland, Maine, appointed Jim New CEO and added Paul Goldenheim to its board

BioMarin Pharmaceutical Inc., of Novato, Calif., appointed William D. Young and Kenneth M. Bate to its board...Celgene Corp., of Summit, N.J., appointed Jacqualyn A. Fouse senior vice president and chief financial officer...Cubist Pharmaceuticals Inc., of Lexington, Mass., promoted Steven C. Gilman to executive vice president of R&D and chief scientific officer

in Europe, Asia and Latin America...He previously served as executive vice president of Abbott Corp., of Abbott Park, Ill., and president of its pharmaceutics division, in addtion to group president for Europe and subsequently president of Abbott International

to chief operating officer and David R. Holland to senior vice president of sales and marketing...Myers, Fla., appointed Grant Carlson vice president of business development and named Mark W. Smits vice president of sales and marketing effective Aug. 30, 2010