Premier Research Group plc, of Philadelphia, appointed Anthony Faragasso, executive director and global head of medical management and safety...Somnus Therapeutics Inc., of Bedminster, N.J., named Gary Cupit, Mary Osbakken, Christine Blumhardt, Linda Hogan and Anne McCormick to its executive development team

Altus Pharmaceuticals Inc., of Cambridge, Mass., appointed Georges Gemayel, CEO and member of the board...Ariad Pharmaceuticals Inc., of Cambridge, Mass., appointed Raymond T. Keane vice president, general counsel and chief compliance officer...Endo Pharmaceuticals Holdings Inc., of Chadds Ford, Pa., named Blaine T. Davis vice president of investor relations and corporate communications

Sigma-Aldrich, of St. Louis, said Chief Administrative Officer and Chief Financial Officer Michael R. Hogan will retire this summer...He will become an unpaid vice president and outside director of the Sigma-Aldrich Foundation...Vyteris Inc., of Fair Lawn, N.J., appointed Haro Hartounian president and Joseph Himy chief financial officer

Dyax Corp., of Cambridge, Mass., named Mark J. Sawyer as senior vice president of process sciences and technical operations

Oragenics Inc., of Alachua, Fla., named Marc Siegel and Kevin Sills to its board...Oxford BioMedica, of Oxford, UK, appointed Alan Kingsman chairman and promoted Mike McDonald to CEO...Phytomedics Inc., of Jamesburg, N.J., named Laurie Smaldone Alsup president and CEO

MacroGenics Inc., of Rockville, Md., appointed Jean-Christophe Tellier executive vice president and chief commercial officer and James Karrels vice president and chief financial officer...MannKind Corp., of Valencia, Calif., named Matthew J. Pfeffer corporate vice president and chief financial officer

Egenix Inc., of New York, appointed Donald C. Fresne chairman and CEO and named Daniel Petrylak chairman of its scientific advisory board...GeneNews Ltd., of Toronto, elected Harry A. Glorikian and Fran Tuttle to its board

Senomyx Inc., of San Diego, appointed Roger D. Billingsley director and a member of the corporate governance and nominating committee...The company also named Kent Snyder chairman of the board and Jay M. Short lead independent director

Medivation Inc., of San Francisco, appointed Michele D. Bronson vice president, regulatory and quality...Minrad International Inc., of Orchard park, N.Y., appointed David T. DiGiacinto president and chief operating officer...Monogram Biosciences Inc., of South San Francisco promoted Gordon Parry to vice president, research and development, oncology

Adventrx Pharmaceuticals Inc., of San Diego, named Mark Bagnall executive vice president and chief financial officer...Agendia BV, of Amsterdam, the Netherlands, appointed Richard A. Bender vice president and chief medical officer...Synthetic Genomics Inc., of La Jolla, Calif., appointed Chuck McBride executive vice president and chief financial officer

MPM Capital, of Boston, appointed Robert Millman and Elizabeth Stoner executive partners...Oragenics Inc., of Alachua, Fla., appointed Derek Hennecke and Stanley B. Stein to its board of directors...Predictive Biosciences, of Lexington, Mass., appointed Peter Klemm president, director and CEO

Bionovo Inc., of Emeryville, Calif., appointed George Butler and Louis Drapeau to its board of directors...The company also named Mark Suto vice president of chemical and pharmaceutical sciences...Senetek Plc, of Napa, Calif., named Michael Campagnoli executive director and Phillip Rose consultant for sales and marketing

The company also established a strategic commercialization and partnership committee consisting of directors Peter D. Kiernan III, Neil W. Flanzraich and Georg Nebgen...Modigene Inc., of Nes-Ziona, Israel, named Marian Gorecki and Steven D. Rubin to its board and appointed Phillip Frost chairman

Genzyme Corp., of Cambridge, Mass., named Maggie Shafmaster senior vice president and chief patent counsel...Metabolix Inc., of Cambridge, Mass., named Richard P. Eno president and CEO...Osiris Therapeutics Inc., of Columbia, Md., named Jeffry Lawrence executive medical director and Jesus Soriano senior director of business development

The company also named Kevin M. Forrest and R. Andrew McMillan principals...Solace Pharmaceuticals, of Boston, named Alasdair Naylor head of research and Marie Lossky director of business development and intellectual property...Trimeris Inc., of Morrisville, N.C., appointed Arthur B. Cohen and Joseph P. Healey to its board of directors

Memory Pharmaceuticals Corp., of Montvale, N.J., appointed Vaughn M. Kailian interim president and CEO...Jim Sulat, the previous president and CEO, will be chief financial executive on a part-time basis...OPKO Health Inc., of Miami, appointed Thomas E. Beier and Richard C. Pfenniger Jr

Biomedical Corp., of San Diego, appointed Punit S. Dhillon vice president of finance and operations...Biophan Technologies Inc., of Pittsford, N.Y., appointed Harold Gubnitsky, John Lanzafame and Travis E. Baugh to its board of directors

Affitech AS, of Oslo, Norway, appointed Sergej Kiprijanov vice president of discovery research and preclinical development...Alnylam Pharmaceuticals Inc., of Cambridge, Mass., appointed Edward Scolnick to its board of directors and scientific advisory board...AlphaVax, of Research Triangle Park, N.C., appointed Mark Schleiss, David Bernstein, Robert Pass and Paul D. Griffiths to its cytomegalovirus advisory board and named Robert Olmsted as chairman

Samaritan Pharmaceuticals Inc., of Las Vegas, named Jack L. Ayala and Robert W. Crane to its board of directors...ViroPharma Inc., of Exton, Pa., named Thomas F. Doyle vice president of strategic initiatives and appointed J. Peter Wolf vice president, general counsel and secretary of the board of directors