Proceeds will be used to fund ACT's clinical activities, including its three ongoing Phase I/II trials for forms of macular degeneration, for development of its other clinical activities and for general corporate purposes

Imprimis Pharmaceuticals Inc., of Solana Beach, Calif., said it started a clinical trial testing Impracor, a topical cream designed to deliver ketoprofen

The company said the financing will enable them to complete a clinical study to confirm the positive treatment effects of Oxabact previously seen in patients with primary hyperoxaluria, a rare inborn autosomal genetic disorder leading to markedly elevated levels of endogenous oxalate in plasma and urine

The findings were published in the Journal of Clinical Oncology

KG, which will enable it to take forward two mRNA-based therapeutic cancer vaccines, in clinical development for prostate cancer and non-small-cell lung cancer (NSCLC...The investment comes in the wake of positive clinical data from early stage trials of both CV9103 and NSCLC vaccine CV9201...The financing adds to more than $4 million in nondilutive funding the company has received from Small Business Innovation Research and other grants.

No new safety signals emerged in the study, and the overall safety profile of tofacitinib remained consistent with that seen previously in the RA clinical development program

In fact, about a quarter of NIH employees are paid under Title 42, as well as 44 percent of its researchers and clinical practitioners, according to the report...The bill provides some flexibility by allowing up to 50 employees to be paid without regard to the compensation limitation – if the secretary determines the position is vital.

Proceeds will be used to support clinical studies, R&D activities and for general corporate purposes, including working capital and administrative expenses...Neuralstem Inc., of Rockville, Md., priced a registered direct offering of 7 million shares at $1 apiece for gross proceeds of $7 million to support working capital, capital expenditures, R&D activities, clinical trials and acquisitions of new technologies or businesses...Valeant also said it intends, subject to market and other conditions, to

The study is designed to assess the clinical impact of the absorption profile of BIOD-123 relative to currently marketed mealtime insulin analogues...The clinical response was durable over 180 days...Glenmark's partner, Paris-based Sanofi SA, has licensed all rights to the drug and is carrying out clinical development

We're targeting filing our IND by the second half of 2013, commencing clinical trials thereafter," Shea said...Although our current clinical plan that is funded is specifically to advance the program in diabetic nephropathy, the drug has shown impressive animal results in other diabetic complications, including accelerated atherosclerosis and diabetic retinopathy," Shea said...On Wednesday, Sequenom's shares (NASDAQ:SQNM) gained 28 cents, closing at $3.91.

Clinical response rates were high across all treatment groups and similar to daptomycin

Sanofi Pasteur, of Lyon, France, the vaccines division of Sanofi SA, said clinical results published in The Lancet showed the ability of its vaccine candidate to protect against dengue fever caused by three dengue virus types

The trial is designed to assess the safety and preliminary efficacy of the Neo-Urinary Conduit in up to 10 patients, as well as to translate the surgical procedure successfully used in preclinical animal models into clinical trials with human patients

The company said those findings, presented at the European Thyroid Association meeting in Pisa, Italy, underscored the feasibility of using local pathology confirmation of ATC in future clinical studies

Annovation Biopharma Inc., of Cambridge, Mass., said it raised $8 million in Series A financing led by Atlas Ventures, Partners Innovation Fund and new strategic investor The Medicines Co., of Parsippany, N.J. The funding, which could be expanded to $11 million, is expected to enable preclinical development through clinical proof of concept of the firm's lead, next-generation anesthetic, which is based on technology from Massachusetts General Hospital...Clinical studies are expected to begin in the

The investment will be used to advance the company's PI3-kinase p110-delta/beta and HDAC6 inhibitor programs through early clinical trials in inflammation and cancer

Laboratorios del Dr. Esteve SA, of Barcelona, Spain, published data from three Phase I trials of S1RA E-52862 in the British Journal of Clinical Pharmacology, showing a favorable safety and pharmacokinetic profile...Omeros Corp., of Seattle, said it filed an investigational new drug application to start clinical studies of OMS824, the lead compound from its phosphodiesterase 10 program for schizophrenia and other cognitive disorders

As the cost of conducting clinical trials helps drive drug prices beyond the wallet of many U.S...HHS isn't the only one looking at the cost of clinical trials...The increasing cost of clinical trials has been cited as a big factor in the rising cost of drug development and as a force that's pushing down company valuations

The F3 series was identified through whole-cell screening against clinical Aspergillus fumigatus and Candida albicans...One of the advantages of the infectious disease area is that preclinical models are really predictive of clinical activity," White said...Shares of Repros (NASDAQ:RPRX) gained $1.19, to close Wednesday at $14.23.