Does taking part in a controlled clinical trial of cancer therapy improve one's chances of surviving that disease...The American Federation of Clinical Oncology Societies maintains that treatment in a clinical trial often is a cancer patient's best chance of survival, and that trial access is one of the "basic requirements of quality cancer care

Patients who cannot be treated with existing therapies or who do not meet eligibility requirements for certain drugs can gain information about ongoing clinical trials via the FDA's Clinical Trials Data Bank...For example, the agency has established a web-based system in which firms can submit clinical trial information electronically

The bulk of our capital that we raised is going to go toward clinical and development efforts," Siegall told BioWorld Today...We made progress on every one of our clinical programs and every one of our development programs, and we also announced fantastic partnerships on our technologies," Siegall said...A company representative declined to comment Thursday due to SEC quiet-period rules.

The credit applies to 50 percent of qualified clinical trial expenses incurred with respect to designated orphan drugs, BIO said...law, the agency said.

Science Editor Editor's Note: Science Scan is a roundup of recently published biotechnology-relevant research Rheumatoid arthritis (RA) is among the most crippling forms of joint disease...The chemical name for Arava is leflunomide, and it is in large-scale clinical trials conducted by researchers at the Veterans Affairs medical center jointly with the Washington School of Medicine in St. Louis...That sex bias is particularly prevalent in clinical trials testing treatments for rheumatological

to support future clinical programs and sales and marketing...for clinical development...The rest of the proceeds were designated for general corporate purposes, including potential payments by MEI to parent company Novogen - which makes and sells dietary supplements - under the terms of their license agreement.

Science Editor Editor's Note: Science Scan is a roundup of recently published, biotechnology-relevant research...Loss of function of hepcidin in mice also led to severe iron overload in the animal models, mimicking the human biochemical and clinical phenotypes of juvenile hemochromatosis

Bush Gives FDA Authority On Pediatric Trials President Bush signed legislation authorizing the FDA to force drug companies to conduct clinical trials of adult drugs used off-label in the pediatric population...Opponents to the legislation argue that it will add another layer to the drug-review process and has the potential to discourage off-label use of drugs.

Science Editor Editor's Note: Science Scan is a roundup of recently published, biotechnology-relevant research...From the clinical standpoint, a growing number of failures following the use of these agents has been described

Science Editor Editor's Note: Science Scan is a roundup of recently published, biotechnology-relevant research...Exanta is the first oral anticoagulant to reach late-stage clinical trials since the development of warfarin 50 years ago

Science Editor Editor's Note: Science Scan is a roundup of recently published, biotechnology-relevant research...A large-scale, long-term 70-center clinical trial of an experimental insomnia drug called eszopiclone is reported in the November issue of Sleep, a peer-reviewed publication of the Associated Professional Sleep Societies...The NDA contains a total of 324 clinical trials, which included more than 2,700 adult and elderly subjects, and more than 60 preclinical studies

Science Editor Editor's Note: Science Scan is a roundup of recently published biotechnology-relevant research...Although the main research finding showed no improvement in spasticity scores among patients given cannabinoids compared with placebo, the results suggest that cannabinoids could have potential clinical use for improving patients' mobility and pain control

Science Editor Editor's Note: Science Scan is a roundup of recently published biotechnology-relevant research...From a clinical point of view, it is possible that the changes in the skin are detectable before the other systemic manifestations

Sam Brownback (R-Kan.) and Dianne Feinstein (D-Calif.) wrote a letter to the Senate leadership encouraging them to consider the American Society of Clinical Oncology's (ASCO) proposal to fix the reimbursement system for cancer care in the pending Medicare bill, ASCO said...Pediatric Trials Legislation Hasn't Reached House Legislation requiring drug makers to run clinical trials on adult products that could be used off-label in the pediatric population made it through the Senate in July, but has

Science Editor Editor's Note: Science Scan is a roundup of recently published biotechnology-relevant research...Their report in The Lancet bears the title "Clinical importance of neutralizing antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis...Our findings," the paper's lead author commented, "suggests that the presence of neutralizing antibodies against interferon beta reduces the clinical effect of the drug

Science Editor Editor's Note: Science Scan is a roundup of recently published biotechnology-relevant research...The report suggests that therapeutic drugs already in clinical trials for another disease may be effective for treating HIV-associated dementia...Such MMP2 inhibitors are already in clinical trials for cancer

The company is planning to use the funds for general corporate purposes and for clinical trials of PT-100, its lead product, which is being developed in a Phase I/II trial in combination with Rituxan (Genentech Inc.) in non-Hodgkin's lymphoma and chronic lymphocytic leukemia...If the companies elect to move ahead, they would share worldwide rights.

Its lead product, PI-88, is an anti-angiogenesis cancer drug that has shown promise in clinical trials, Progen said...Ltd.

Science Editor Editor's Note: Science Scan is a roundup of recently published biotechnology-relevant research...The actual use of EZH2 as a clinical test is still several years away, though the U-M team is planning a prospective clinical trial to test its use in breast cancer patients