Serono SA, of Rockland, Mass., reported 24-week results from a completed clinical trial of Serostim...Phase I clinical trials with repeat dosing will now be finalized and evaluated...PDF inhibitors target an enzyme that is essential to bacteria but not required in human cells.

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...He added, "This study establishes unequivocally that the normalcy of surviving cloned animals should not be based on superficial clinical examinations, but rather on detailed molecular analysis of tissues from adult cloned animals...The controlled clinical trial enrolled 2,074 women with ovarian cancer from 130 centers in eight countries

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...That means a blood sample is drawn and sent to a clinical laboratory

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...The paper concludes: "Given that there is currently no therapy for end-stage heart failure aside from heart transplantation, future studies are warranted to translate these findings into larger animal models and the clinical setting

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...In contrast to acquired clinical immunity," the Nature paper points out, "anti-parasite immunity takes many years to develop and is easily lost, reflecting the problems of antigenic diversity...They point out that their in vivo experiment differs significantly from current clinical practice, suggesting that there is no immediate cause for concern

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...They showed no clinical disease 330 days after inoculation plus repeated therapy, compared with 180 days without treatment

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...They make the point that the clinical presentation and outcome of anthrax in humans depend on the spore's route of entry into the body

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...Efforts to develop maytansine into a clinically useful anticancer drug proved disappointing in Phase II clinical trials in the 1980s, probably because of dose-limiting toxicity in humans

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...And third among the gang-of-three co-infections: "Clinical malaria occurs with an increasing frequency and severity in HIV-1-infected individuals, especially during pregnancy...Furthermore," the paper pointed out, "HIV-1 infection roughly doubles the risk of clinical malaria in non-pregnant adults

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...Our paper shows that cytokines are the primary clinical players here," he pointed out...Ferrara summed up the novel drug-therapy strategies now beginning clinical trials

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...CPHPC is about to undergo clinical trials of safety and efficacy in five Alzheimer's patients

Science Editor Editor's note: Science Scan is a roundup of recently published biotechnology-relevant research...This widespread clinical reliance has duly led to increasing bacterial resistance to these antibiotics...But the resistance factor was discovered four years ago on a plasmid from a clinical isolate in the microbe Klebsiella pneumoniae

Science Editor Editor’s note: Science Scan is a roundup of recently published biotechnology-relevant research...The lack of an adequate treatment for the condition has stimulated numerous experimental and clinical studies for development of effective therapeutic strategies

The report suggests that increased funding is only a part of the solution, and that more pluralism in funding sources, lower dependence on closed national systems, and higher integration of research with teaching, clinical research and medical practice should become priorities of a European research policy for biotechnology...Submissions are being invited from organizations or groups of organizations from the 15 EU member states and the 13 EU candidate countries, but entities from other countries

Science Editor Editor’s note: Science Scan is a roundup of recently published biotechnology-relevant research...Now a large-scale clinical trial reports that calcium intake also has beneficial effects on high-density lipoprotein (HDL) the “good” cholesterol

Science Editor Editor’s note: Science Scan is a roundup of recently published biotechnology-relevant research...Numerous anti-angiogenic drugs are in clinical trials, but the growing tumors soon beat them back with drug resistance factors

Science Editor Editor’s note: Science Scan is a roundup of recently published biotechnology-relevant research...When a physician or psychiatrist diagnoses clinical anxiety in his patient, the practitioner reaches for his Physician’s Desk Reference (PDR

Science Editor Editor’s note: Science Scan is a roundup of recently published biotechnology-relevant research...is of clinical interest because raloxifene is a SERM that is approved for treatment or prevention of osteoporosis...There’s a large double-blind clinical trial going on internationally at present,” Brown noted, “both in the U.S

Science Editor Editor’s note: Science Scan is a roundup of recently published biotechnology-relevant research...Both forms have similar clinical and pathological features