Another $406 million could come in the form of clinical, regulatory and commercial milestones, and Enanta would be eligible for tiered, double-digit royalties and a U.S...Net proceeds are expected to support clinical trial costs and acquisition of manufacturing equipment, leasehold improvements and general corporate purposes...Trimel's pipeline includes CompleoTRT, a bioadhesive intranasal testosterone gel for male hypogonadism.

The company also is preparing a clinical program for marketing in Europe and the U.S

The German Federal State of Saxony and the European Union funded the grant, which supplements a grant awarded by the SAB in August 2011 for the CANVAS clinical trial...Net proceeds of about $12 million will be used to support R&D, acquisition of intellectual property related to complementary drug therapies, clinical trials and other expenses...The first tranche of the Series B closed in June 2012 for $8.6 million.

The NX03-0040 prostate cancer clinical study of 150 men is testing low (2.5 mg) and high (15 mg) single doses of NX-1207 for the effect to eradicate or shrink low-grade localized prostate cancer tumors

Secondary objectives of the trial include clinical activity by serum TTR levels...The study showed that Uceris 9 mg gave a statistically significant benefit over placebo for the primary endpoint of clinical and endoscopic remission at week eight...For the Uceris 9-mg group, 17.4 percent of patients achieved clinical and endoscopic remission, compared to 4.5 percent of the placebo group (p = 0.0047

The company also said it is initiating a new financing round – about $6 million in new convertible debt – to fund further clinical development

Cerus anticipates using the net proceeds for clinical development and other R&D activities related to the Intercept Blood System, preparatory activities for the potential commercialization of the system in the U.S...The funds, along with those received in January, will help advance the company's therapeutic programs toward clinical stage, building upon recently announced preclinical data for both the Parkinson's and liver disease programs

Cytos Biotechnology Ltd., of Zurich, Switzerland, said results from a Phase IIa trial showed that CYT003, an immune modulator for the potential treatment of asthma, met all clinical endpoints, with patients treated with CYT003 having their asthma control improved despite the withdrawal of inhaled corticosteroids (ICS...The study also will assess secondary measures of clinical benefit, including progression-free survival, objective response rate and overall survival at six months and 12 months

Proceeds will be used to fund clinical trials of IMO-8400, an agonist of Toll-like receptors 7, 8 and 9, which is in development for autoimmune and inflammatory diseases, as well as for working capital and other general corporate purposes

The study design calls for the collection of 5,250 clinical endpoints, and Merck remains blinded to the actual results of the analysis and to other safety and efficacy data

Inc., of Whitehouse Station, N.J., said researchers from the Clinical Trial Service Unit at Oxford University presented results from the HPS2-THRIVE (Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events) study of Tredaptive (extended-release niacin/laropiprant) during the late-breaking clinical trial session at the American College of Cardiology 62nd Annual Scientific Session in San Francisco...Findings were presented during the late-breaking clinical trial session

Janssen and partner Bayer AG, of Leverkusen, Germany, will enroll patients into five global clinical trials, which will involve a total of 28,850 patients

Zealand Pharma A/S, of Copenhagen, Denmark, disclosed in a pipeline update that it plans to advance danegaptide into a single site clinical efficacy study to further profile the peptide drug in cardio protection

The company plans to use proceeds from the offering to complete clinical development of Ravicti in hepatic encephalopathy (HE) and to fund post-approval studies in UCD...at the same unit price.

The ATX-101 global clinical development program has enrolled more than 2,500 total patients, of which more than 1,500 have been treated with ATX-101, the company said

Vertex Pharmaceuticals Inc., of Cambridge, Mass., said VX-787 in a Phase II influenza challenge study resulted in statistically significant improvements in viral and clinical measurements of infection...Also, 93 percent of people in that dose group showed no clinical symptoms of influenza after three days of treatment, compared to 41 percent of people in the placebo group

Boehringer Ingelheim Pharmaceuticals Inc., of Ridgefield, Conn., part of Boehringer Ingelheim GmbH, reported the first interim results in HCV/HIV co-infected patients from the company's ongoing hepatitis C (HCV) clinical trial program, HCVerso...Polyphor Ltd., of Allschwil, Switzerland, completed a Phase I trial demonstrating the clinical safety and tolerability of its Pseudomonas-specific antibiotic POL7080...The study compared the efficacy and safety of once-weekly Milprosa to daily 8 percent

In total, Ablynx has five products in clinical development and six in preclinical development, of which five are with partners...At the completion of the capital raising, Bionomics will have approximately $26 million in cash.

Dezima Pharma BV, of Naarden, the Netherlands, said it raised €14.2 million (US$18.6 million) for the clinical development of its cholesteryl ester transfer protein (CETP) inhibitor, DEZ-001 (previously TA-8995), and to develop additional earlier-stage dyslipidemia assets...It also will support preparatory work to advance the firm's clinical-stage oncology program, DPX-Survivac, into Phase II development...It will use the proceeds to advance its opthalmic programs through clinical proof of concept