Assuming the final clinical study report supports the preliminary findings, RedHill said it will consider filing for U.S

CSL Behring is developing rVIIa-FP as a treatment for hemophilia A and hemophilia B patients who have inhibitors as part of the PROLONG 7- FP clinical study program

Serendipitously, independent clinical studies of the antecedent biomarkers of AD seem to have corroborated Satori's approach, he added

The project, "Human genetics-driven discovery of memory-modulating drugs," will start in March and will include three clinical studies supported by a CTI grant for three years...Niiki Pharma Inc., of Hoboken, N.J., said it completed the dose-escalation portion of its Phase I trial of NKP-1339, a small molecule designed to down-regulate GRP78, a tumor survival and anti-apoptosis factor

Radius Health Inc., of Cambridge, Mass., reported that its transdermal BA058 microneedle patch, for osteoporosis, showed positive results in a Phase Ib clinical study...UCB Pharma SA, of Brussels, Belgium, began a trial (EXXELERATE) of Cimzia (certolizumab pegol) plus methotrexate compared with Humira (adalimumab) plus methotrexate for rheumatoid arthritis

It's a great fit with clinical need and best suited to deal with the three major factors associated with myelofibrosis...Alnylam Pharmaceuticals Inc., of Cambridge, Mass., reported clinical data from a number of programs...Astellas Pharma Inc., of Tokyo, and Ambit Biosciences Corp., of San Diego, shared updated results from an interim analysis of a Phase II trial of quizartinib (previously AC220) in acute myeloid leukemia, showing that quizartinib monotherapy had activity in refractory and relapsed

Bellicum Pharmaceuticals Inc., of Houston, reported that the results of the first clinical study of its CaspaCIDe technology showed that it worked quickly and effectively without compromising the function of the cell and may have broad application as a safety feature for cell therapy...Clinical follow-up, completed three months after the administration of PLX-PAD cells, noted statistically significant improvements in several parameters, including ankle-brachial index (p = 0.033), transcutaneous

The financing will allow Tensha to advance its lead program through clinical proof of concept, lay the groundwork for clinical studies in other cancer indications and advance the preclinical development of bromodomain inhibitors in areas outside of oncology, according to Onsi, who declined to speculate on a timetable for any investigational new drug filings

The lead liquid formulation, PUR003, previously had shown safety and tolerability in patients with asthma and influenza, and, with the latest funding in hand, the firm plans to launch five clinical studies of dry powder candidate PUR118, starting with two Phase Ib trials in COPD...In COPD, the company will need some big pharma muscle

For now the company's scientific founders, David Woodley and Mei Chen at USC, have just received a National Institutes of Health grant for a clinical study of the recombinant protein in epidermolysis bullosa patients...A.P. Pharma Inc., of Redwood City, Calif., entered a definitive agreement with new and existing investors to raise $24 million in a private placement of common stock and warrants

OncoSec said it intends to use proceeds from the offering for further development of its ElectroOncology therapies to treat cancers, for clinical studies and for general corporate purposes.

Adeona Pharmaceuticals Inc., of Ann Arbor, Mich., announced that analyses of a clinical study evaluating reaZin, a gastroretentive, sustained-release, once-daily oral tablet formulated from zinc (150 mg) and amino acid cysteine (100 mg) for treatment of Alzheimer's disease, indicated that the older the reaZin treatment patient, the greater the amount of cognitive benefit compared to the placebo patients of the same age...NovaDel Pharma Inc., of Bridgewater, N.J., opened an investigational new drug

We have a network of pharma experts who all told us, if it was their compound it would be given the green light to go into clinical development...The company said it will use the funds to complete Phase IIa studies with lead Smac mimetic drug candidate, TL32711, in solid tumors and to initiate clinical studies in hematological cancers.

Meritage Pharma Inc., of San Diego, said a Phase IIb trial of oral budesonide suspension for eosinophilic esophagitis met its primary endpoin...The proposed revision would permit participants to receive either docetaxel re-treatment or cabazitaxel as chemotherapy in the clinical study

A.P. Pharma Inc., of Redwood City, Calif., will raise $4.5 million in convertible notes in a private placement deal with certain investors, including Tang Capital Partners...The discussion topics included dosing system, clarification of assays for manufacture and quality control, and a QT/metabolism clinical study

Under the agreement, GTC would receive an initial inventory of bulk drug substance for use in clinical studies...Merrimack's first major pharma deal, in 2009, focused on MM-121

The two companies share equally the cost of Phase II and Phase III clinical studies...ArQule's clinical pipeline additionally includes ARQ 621, an Eg5 inhibitor, in Phase I and ARQ 736, a pan-RAF inhibitor

Clinical studies are slated to start in early 2011

The Horizant NDA resubmission also included a final safety update, which provided updated and new safety information on patients in clinical studies who have been treated with the drug...Geron said it plans to use the net proceeds for R&D, including clinical trials for its product candidates, development activities for in-licensed products and other general corporate purposes