Scientists will use those samples to assess the T-cell mediated interferon gamma response to the T-cell epitopes, and the company will evaluate those results in preparation for further clinical studies...Shares of Theratechnologies (TSX:TH) closed at C$9.53 (US$9.54) Tuesday, down C12 cents.

Novagali Pharma, of Evry, France, said the FDA has approved its investigational new drug application to conduct a Phase I clinical trial of Nova63035, an ophthalmic injectable emulsion based on Eyeject technology containing a corticosteroid prodrug for the treatment of diabetic macular edema, a severe form of diabetic retinopathy, a common complication of diabetes that affects about 50 percent of patients...The Phase I clinical study, to be performed in Denmark, is a double-blind and within-group

Also in the works are plans to begin a Phase III clinical study of a twice-daily tramadol-acetaminophen combination formulation, a twice-daily acetaminophen formulation and a misuse-prevention platform...The company said it will use the proceeds to advance its research in multiple myeloma with the goal of initiating a Phase I clinical trial.

Celgene International Sarl, of Boudry, Switzerland, said clinical data from two ongoing Revlimid (lenalidomide) studies in relapsed/refractory aggressive non-Hodgkins lymphoma showed activity in the initial analysis of the first 46 patients of a 200-patient Phase II multicenter, open-label clinical study, NHL-003

The clinical trial is expected to enroll up to 50 patients in up to 12 centers throughout the U.S. The company expects to report clinical trial results in the first half of 2008...Titan Pharmaceuticals Inc., of South San Francisco, revealed the early completion of enrollment in its Phase III clinical study of Probuphine in the treatment of opioid dependence

BioGeneriX AG, of Mannheim, Germany, announced positive data from two Phase I clinical studies of GlycoPEG-GCSF for the treatment of neutropenia associated with myelosuppressive chemotherapy...LifeCycle Pharma A/S, of Horsholm, Denmark, said results from a Phase I head-to-head clinical trial comparing LCP-Tacro, its lead product candidate being developed as a once-daily tablet version of tacrolimus, showed that LCP-Tacro proved superior to Advagraf (tacrolimus prolonged release, Astellas Pharma Inc

Results also showed that the drug was safe and well tolerated in clinical studies...IDM Pharma Inc., of Irvine, Calif., reported updated results from a Phase II trial of melanoma vaccine Uvidem, showing that the drug induced immune response and was well tolerated in patients with advanced disease

SIOPEL centers in up to 33 other countries also are expected to participate in the multicenter, prospective, randomized Phase III clinical study of about 100 evaluable children with hepatoblastoma being treated with cisplatin...Inovio Biomedical Corp., of San Diego, said partner Tripep AB, of Huddinge, Sweden, has begun enrolling patients for its Phase I/II clinical study of a novel DNA vaccine designed to treat chronically infected hepatitis C virus patients

In a Phase I clinical study, an ovarian cancer patient with the clear-cell subtype experienced a durable partial response to the compound lasting over three years after failing three prior chemotherapy regimens

Amicus Therapeutics, of Cranbury, N.J., announced positive results from two recently completed Phase I clinical studies of AT2220 (1-deoxynojirimycin HCl) for Pompe disease...MGI Pharma Inc., of Minneapolis, said results of a randomized, double-blind, multi-center, pivotal Phase III trial of Aquavan (fospropofol disodium) Injection in patients undergoing flexible bronchoscopy showed it met its primary and secondary endpoints

Akela Pharma Inc. (formerly LAB International Inc.), of Montreal, initiated a Phase IIb asthma trial of CGRP, a 37 amino acid, natural neuropeptide produced in the lung in response to allergic stimuli...The ongoing Alferon N West Nile Virus study is the only well-controlled clinical study being conducted in the United States at this time, Hemispherx Biopharma said

Tranzyme Pharma Inc., of Research Triangle Park, N.C., started a Phase IIb trial of TZP-101, a ghrelin agonist, in postoperative ileus...Uluru Inc., of Addison, Texas, began a clinical study to evaluate the mobility of severely burned joints treated with its Hydrogel Nanoparticle Wound Dressing

Preclinical and early clinical studies suggested that active levofloxacin concentrations in pulmonary tissues after MP-376 administration are increased compared to those achieved when the antibiotic is delivered by other routes of administration

Interleukin Genetics Inc., of Waltham, Mass., completed patient enrollment in clinical studies in Japan and China as part of its preparation for the anticipated launch of genetic tests in Asian markets in 2009...LifeCycle Pharma A/S, of Horsholm, Denmark, said it will initiate a Phase II trial of LCP-AtorFen, a fixed-dose combination of atorvastatin and fenofibrate, to treat high cholesterol levels

Money also will be used to advance clinical development programs, pursue additional in-licensing opportunities and for other general corporate purposes...Net proceeds will be used to support general corporate purposes, including the funding of its research and development programs, such as bepotastine, strong steroid, Xibrom and steroid combination product, and ecabet sodium clinical studies

4SC AG, of Planegg-Martinsried, Germany, has completed patient recruitment for the Phase IIa clinical trial with its drug candidate SC12267 for the treatment of rheumatoid arthritis...Millennium Pharmaceuticals Inc., of Cambridge, Mass., presented data from four clinical trials showing that Velcade (bortezomib) in combination with various other cancer drugs improved survival and generated complete responses in first-line treatment of multiple myeloma...Speedel Holding AG, of Basel, Switzerland, said

Inflazyme Pharmaceuticals Ltd., of Vancouver, British Columbia, said a review of study reports for IPL455,903, a PDE4 inhibitor, showed that data might support further clinical studies, as well as support development of Inflazyme's other PDE4 inhibitors...Kythera gained exclusive worldwide rights to the product in November from Basel, Switzerland-based Novartis Pharma AG

LifeCycle Pharma, of Horsholm, Denmark, will initiate a Phase II clinical trial of LCP-Tacro for the prevention of organ rejection in kidney transplant patients following an update of its initial investigational new drug application to the FDA...Theravance Inc., of South San Francisco, has enrolled the last patient in its Phase III clinical study of the investigational antibiotic telavancin in patients with hospital-acquired pneumonia due to gram-positive bacteria, including resistant strains such

NovaDel Pharma Inc., of Flemington, N.J., said data from two clinical studies comparing zolpidem oral spray with zolpidem tablets (Ambien, Sanofi-aventis Group) support a new drug application filing this year under the 505(b)(2) regulatory process