Affymax will continue to trade under the symbol "AFFY...Royalty Pharma, of New York, increased its hostile bid to acquire Elan Corp

The company expects its common stock to begin trading on the NYSE market on June 17, under its current ticker symbol, "AMPE...Royalty Pharma, of New York, extended until June 21 the $6.4 billion offer to buy Elan Corp...The company expects to enter a third agreement (separation agreement) governing other terms of the firms' business relationship

Horizon Pharma Inc., of Deerfield, Ill., said in an SEC filing that it provided written notice to Mallinckrodt LLC, the pharmaceuticals business of Dublin, Ireland-based Covidien LLC, of the termination of the companies' co-promotion agreement dated June 14, 2012, effective 30 days after the date of such notice...Novavax said it plans to make a separate, private offer for outstanding stock options, issuing 218,120 shares of Novavax common stock, corresponding to a value of SEK 8.30 (US$1 .26) for

Maxygen Inc., of Redwood City, Calif., said its board approved the liquidation and dissolution of the company, subject to shareholder approval, and plans to distribute all available cash to its shareholders after making reasonable provision for known and potential liabilities and other obligations of the company...Maxygen estimated that the aggregate amount of the initial liquidating distribution to stockholders will be between $68.2 million and $69.6 million, or between $2.45 to $2.50 per share

Astellas Pharma Europe BV, of Meppel, The Netherlands, a subsidiary of Astellas Pharma Inc., reported the Dutch Medicines Evaluation Board granted marketing authorization for Vesomni (solifenacin + tamsulosin) in the Netherlands...Perrigo Co., of Allegan, Mich., is transferring the listing of its U.S.-traded common stock to the New York Stock Exchange (NYSE) from Nasdaq

Also, it revises the proposal to decrease the total number of authorized shares of common stock, dropping the total number of authorized shares of common stock post-reverse stock split to 50 million shares (in the earlier proxy, Advaxis proposed a total number of 300 million shares of common stock post-reverse stock split...Another revised proposal to approve an amendment to the 2011 Omnibus Incentive Plan, calls for a limit to the amount of the requested increase to 75 million shares of common

to repurchase $5 billion of common stock...Proceeds from Merck's recently concluded debt offering were used to execute the ASR, which is part of the big pharma's previously disclosed $15 billion share repurchase program

The company plans to use proceeds to repurchase common stock and for general corporate purposes, including the repayment of outstanding commercial paper borrowings and upcoming debt maturities

plc, of Dublin, Ireland, published a response to an offer made by Echo Pharma Acquisition Ltd. (Royalty Pharma) on May 2...Helsinn Healthcare SA, of Lugano, Switzerland, and Vifor Pharma, of Villars-sur-Glane, Switzerland, signed an exclusive license and distribution agreement for netupitant-palonosetron fixed-dose combination, an investigational Helsinn product for chemotherapy-induced nausea and vomiting, giving rights to Vifor to distribute the product in Switzerland, France, Spain, Portugal

Common stock in Fibrocell Science Inc., of Exton, Pa., has been approved for listing on the NYSE Market, to commence trading on May 17, under the ticker symbol FCSC

The split is intended to increase the per-share trading price of the common stock to satisfy the $1 minimum bid price requirement for continued listing on the Nasdaq Capital Market

turned its attention to other candidates in its pipeline...The Carlsbad, Calif.-based company priced an underwritten public offering of 9 million shares of its common stock at $19 per share, seeking to raise $171 million from the offering, which is expected to close on or about May 14...continue to view shares as undervalued based on the >$1B potential of ISIS-SMN-Rx, as well as the promise of ISIS-TTR-Rx and Isis' 20+ other pipeline candidates," he wrote

The company expects to repurchase about $7.5 billion of common stock over the next 12 months, financed through a combination of debt issuance and operating cash flows, with the remainder to be repurchased over time with no time limit

26, 2017, at an interest rate of 13 percent, and the conversion rate will be re-priced from $3.78 to $1.25 per share of common stock...Due to third-party manufacturing issues, distribution of Janssen Products LP's Caelyx in Europe has been intermittently disrupted since 2011

flutemetamol to help select patients for a Phase I trial testing Eisai's E2609, a BACE inhibitor for the potential treatment of Alzheimer's disease...The Antimonopoly Committee of Ukraine gave approval to Valeant Pharmaceuticals International Inc., of Laval, Quebec, for its proposed acquisition of Obagi Medical Products Inc., of Long Beach, Calif...AMC approval is one of the conditions for consummation of its tender offer for all outstanding shares of common stock in Obagi at $24 per share

Addex Therapeutics, of Geneva, said regulatory authorities in the Netherlands gave approval to start in the first half of this year a Phase I study of ADX71441, a GABA-B receptor positive allosteric modulator, for Charcot-Marie-Tooth1A (CMT1A) neuropathy and other disease indications...Tranzyme Pharma Inc., of Research Triangle Park, N.C., and Ocera Therapeutics Inc., of San Diego, entered a definitive agreement under which Ocera will merge with a subsidiary of Tranzyme in an all-stock transaction

The company is also reducing the number of shares of common stock from 1,5000,000,000 to 100,000,000...BioAlliance Pharma SA, of Paris, said it received marketing authorization from the FDA for Sitavig (acyclovir Lauriad) in the treatment of recurring herpes labialis, marking the successful conclusion to the assessment procedure carried out by the American authorities...To date, 60 people have been confirmed infected with H7N9 in China, with 13 deaths

Merz Pharma Group, of Frankfurt, Germany, said it withdrew its nonbinding proposal to acquire the outstanding common stock of Obagi Medical Products Inc., of Long Beach, Calif., for $22 per share in cash...NovaDel Pharma Inc., of Bridgewater, N.J., signed a definitive agreement to sell its NovaMist technology and certain additional assets, including related patents and trademarks, to Australia's Suda Ltd

DFH Pharma Inc., of Gaithersburg, Md., said it entered a research and product development agreement with Hetero Group, a research-based pharmaceutical group headquartered in Hyderabad, India, to develop next-generation HIV maturation inhibitor drugs...Tris Pharma Inc., of Monmouth Junction, N.J., said the FDA approved its new drug application for Karbinal ER (carbinoxamine maleate) extended-release oral suspension, a sustained-release histamine receptor blocking agent indicated for the treatment of