That financing was led by Bio*One Capital, part of the Singapore Economic Development Board (EDB), and venture capital firm Aravis Venture. (See BioWorld Today, Oct. 21, 2008.) Privately held S*Bio was established in 2000 as a joint venture of the EDB Investments and vaccine developer Chiron Corp. (acquired by Novartis AG in 2006

The privately held biotech was established in 2000 as a joint venture of the EDB Investments and vaccine developer Chiron Corp. (acquired by Novartis AG in 2006

CNSI is a partnership between UCLA and UC Santa Barbara, established in 2000 through a state of California initiative to combine academic research and the private sector

Henningsdorf, Germany-based Revotar was established in 2000 as a majority-owned subsidiary of Houston-based Texas Biotechnology Corp., later Encysive Pharmaceuticals Inc., which New York-based Pfizer Inc

The new company includes the recently acquired AC Biotec GmbH. (See BioWorld Today, July 29, 2008.) Direvo itself was established in 2000 as a spinout from the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany, and Evotec AG, from which it licensed confocal imaging technology

Cologne, Germany-based Direvo was established in 2000 as a spin-out from the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany, and Evotec AG, from which it licensed confocal imaging technology

Gilde has exited from five investments held by its first fund, which was established in 2000

A French National Registry was established in 2000, enrolling 674 patients from 2002 to 2003, with a goal of updating the data gained through the NIH effort

NatImmune, which was established in 2000 by Alan Ezekowitz, professor of pediatrics at Harvard Medical School in Boston, and Jens Jensenius, professor of immunology at Aarhus University in Denmark, has raised $35 million to date

NatImmune, which was established in 2000 by Alan Ezekowitz, professor of pediatrics at Harvard Medical School in Boston, and Jens Jensenius, professor of immunology at Aarhus University in Denmark, has raised $35 million to date

TopoTarget, which was established in 2000, acquired Prolifix Ltd., of Abingdon, UK, and G2M Cancer Drugs AG, of Frankfurt, Germany, during its existence as a privately held company

Erimos was established in 2000 as Biocure Medical, a joint venture between a private investor and John Hopkins University in Baltimore, where professor Ru Chih Huang had been evaluating the possible use of nordihydroguaiaretic acid (NDGA) to treat diseases such as HIV

REV was established in 2000 with an initial fund of $100 million and an aim to invest in late-stage businesses with the potential to provide Reed Elsevier with new technologies, product services or customers

REV was established in 2000 with an initial fund of $100 million and an aim to invest in late-stage businesses with the potential to provide Reed Elsevier with new technologies, product services or customers

Actelion, which was formed in 1997, was a founding shareholder in Axovan, established in 2000, and currently holds close to 9 percent of the company

Address 1000 Marina Boulevard, Suite 450, Brisbane, CA 94005 Phone number (650) 829-2600 Fax number (650) 829-2647 Internet address www.x-mine.com Management Sandip Ray, president and CEO Thomas Neff, chairman Todd Golub, director Tadashi Matsumoto, director Rory Riggs, director Year Established 2000 Employees 4 Business/Strategy X-Mine Inc

Address 400 West Cummings Park, Suite 2850, Woburn, MA 01801 Phone number (781) 938-3830 Fax number (781) 938-3880 Internet address www.silicoinsights.com Management Dinesh Patel, chairman John Babish, vice president of research Nandan Padukone, president and COO Christos Hatzis, vice president of technology Lynne Selinger, associate director of corporate operations Year Established 2000 Employees 12 Business/Strategy Silico Insights Inc

Address 270 Littlefield Avenue, South San Francisco, CA 94080 Phone number (650) 266-1400 Fax number (650) 266-1460 Internet address www.renovis.com Management Corey Goodman, director, president and CEO John Doyle, vice president and CFO Tito Serafini, chief discovery scientist and vice president of genomic research Lynne Zydowsky, COO, director and senior vice president of business development Year Established 2000 Employees 37 Business/Strategy Renovis Inc

Address 19 Firstfield Road, Gaithersburg, MD 20878 Phone number (301) 556-1300 Fax number (301) 556-1350 Internet address www.psygenomics.com Management Richard Chipkin, CEO David Theil, CFO Michael Palfreyman, president and CSO Year Established 2000 Employees 41 Business/Strategy Psychiatric Genomics Inc