Since running a screen is the first step for many projects, we thought if we break it down, the early stage of a collaboration will move more quickly because it

Early stage ADCs using less stable linking technologies are inherently imprecise and less efficient, translating into smaller payloads of the targeted agent actually reaching a tumor cell, agreed Trevor Hallam, chief scientific officer of San Francisco-based Sutro Biopharma Inc., another developer of next-generation ADCs. (See BioWorld Today, Dec. 19, 2012.) Site-specific conjugations result in more precise targeting and more homogenous products that are easier for regulators to review

That represents a shift from its original strategy, involving earlier-stage companies approaching commercialization

That represents a shift from its original strategy, involving earlier-stage companies approaching commercialization

LONDON – Merck Serono is enlarging its venture fund from €40 million to €100 million (US$51 million to $128 million) – increasing its capacity to invest in early stage companies, technologies and products that can be shaped up for the company's internal pipeline...And although other pharma companies have established VC funds with a similar aim of accessing innovation, Bulthuis said the overall shortage of funding for early stage companies means the competition for assets is not intense

They include a pegylated interferon-alpha-2b, in development for the bone marrow disorder polycythemia vera, and a dendritic cell therapy for treating glioblastoma, which its subsidiary Activartis Biotech GmbH, also of Vienna, is developing. (See BioWorld Today, April 10, 2003.) Market Diversification Newbridge, based in Dubai, in the United Arab Emirates, is an earlier-stage venture

Since running a screen is the first step for many projects, we thought if we break it down, the early stage of a collaboration will move more quickly because it

They include a pegylated interferon-alpha-2b, in development for the bone marrow disorder polycythemia vera, and a dendritic cell therapy for treating glioblastoma, which its subsidiary Activartis Biotech GmbH, also of Vienna, is developing. (See BioWorld Today, April 10, 2003.) Market Diversification Newbridge, based in Dubai, in the United Arab Emirates, is an earlier stage venture

In short, the company concluded the study was appropriately designed and executed, leading Xenoport with little choice than to terminate the AP program as quickly as possible to conserve cash and shift resources to Horizant and the company's early stage fumarate candidate, XP23829...Xenoport Places Bets in Early Stage BG-12 Prodrug Horizant badly needs a jump start

LONDON – Merck Serono is enlarging its venture fund from €40 million to €100 million (US$51 million to $128 million) – increasing its capacity to invest in early stage companies, technologies and products that can be shaped up for the company's internal pipeline...And although other pharma companies have established VC funds with a similar aim of accessing innovation, Bulthuis said the overall shortage of funding for early stage companies means the competition for assets is not intense

early stage life science companies Avalon will provide up to $30M, while GSK will contribute seed funding, research and development support and success-based preclinical and clinical milestone payments up to a total of $465M for the 10 companies 4/24/13 Merck & Co

Inc. (Whitehouse Station, N.J.) ND Hawaii acquired ownership of a patent family to West Nile virus vaccine technology, together with a nonexclusive license to recombinant protein expression technology Financial terms were not disclosed 4/12/13 Horizon Discovery Ltd. (Cambridge, UK) AstraZeneca plc (London) $75 Deal that provides services and products to applying Horizon Discovery's genome-editing technology to uncover novel targets AstraZeneca gets access to an early stage, first-in-class kinase

But the more common view is that an early stage embryo is an early human life that is not yet a person, and is not the moral equivalent of a baby

Bayer HealthCare Pharmaceuticals Inc., of Wayne, N.J., signed a three-year agreement with the California Institute for Quantitative Biosciences (QB3) to evaluate life sciences start-up companies with the goal of advancing early stage technologies and therapeutics

on the strategy for expanding Radium-223 development, importantly further studies in metastatic castrate-resistant prostate cancer (mCRPC), potentially in combination with oral Zytiga/Xtandi and/or in earlier stage patients, but also a possible Phase II trial in metastatic breast cancer

sales force, a pipeline of small molecules and early stage discovery capabilities...and early stage programs for diabetes and obesity. (See BioWorld Today, May 18, 2010.) The following year, Astellas snagged Perseid for $76 million by exercising an option to buy out the equity interest of a joint venture partner, Maxygen Inc

Actavis Inc., of Parsippany, N.J., on Friday confirmed that it entered early stage discussions with Warner Chilcott plc, of Dublin, Ireland, regarding a potential combination of the two companies

The deal is the first for Shire's strategic alliance with Atlas Venture, which identifies investments for early stage venture creation around rare genetic diseases

has unveiled a shift in strategy away from a sole focus on internally generated compounds, with the in-licensing of an early stage oncology program from Canadian biotech Pharmascience Inc...Most early stage companies don't have the skills to take things forward to something of interest to pharma," Murray said