Compared to a placebo group, animals treated with WF10 showed a reduction of the degree of symptoms

Compared to the placebo group, animals treated with WF10 showed a reduction of the degree of symptoms

In the GFT505-209-4 study, the effect of GFT505 on measured remnant cholesterol was -24 percent (p = 0.0046) compared to the placebo group after 28 days of treatment...Consistently, after three months of treatment in diabetic patients (GFT505-210-5), the effect of GFT505 on calculated remnant cholesterol compared to the placebo group was -46 percent (p = 0.01

Based on an intent-to-treat analysis from the 130-patient randomized trial, patients treated with entinostat saw improved median PFS to 4.3 months vs. 2.3 months in the placebo group

The Phase IIa portion of the trial, which is getting under way shortly, will recruit 144 patients, who will be randomized to one of three dose groups (n = 36) – to receive 0.5 mg/kg of bodyweight, 1.5 mg/kg or 5 mg/kg – or to a placebo group (n = 36

The Phase IIa portion of the trial, which is getting under way shortly, will recruit 144 patients, who will be randomized to one of three dose groups (n = 36) – to received 0.5 mg/kg of bodyweight, 1.5 mg/kg or 5 mg/kg – or to a placebo group (n = 36

The two HPV subtypes were eradicated in 83 percent of the treated CIN2 cohort vs. 33 percent clearance in the placebo group, at six months

in RA now, because the placebo groups don't seem to progress very much – that is, they don't get much worse in the term of the study," and ethical concerns prevent continuing beyond six months

Santhera's original dossier was based on data from a placebo-controlled Phase II trial, but the CHMP considered the vision gains associated with taking the drug to be insignificant – those in the drug treatment group were able to see an additional three letters on a letter chart compared with those in the placebo group

Santhera's original dossier was based on data from a placebo-controlled Phase II trial, but the CHMP considered the vision gains associated with taking the drug to be insignificant – those in the drug treatment group were able to see an additional three letters on a letter chart compared with those in the placebo group

And although the placebo group fared worse, the agency speculated that the dose of buprenorphine delivered by the four implants was simply too low, it being less than a third the dose delivered by 16-mg sublingual buprenorphine

For the Uceris 9-mg group, 17.4 percent of patients achieved clinical and endoscopic remission, compared to 4.5 percent of the placebo group (p = 0.0047

The drug was also well tolerated, with similar rates of occurrence of serious adverse events among drug and placebo groups

primary responder analysis showed 41% in the migalastat group vs. 28% in the placebo group demonstrated a 50% or greater reduction in kidney interstitial capillary GL-3 from baseline to month six 2/19/13 Auxilium Pharmaceuticals Inc. (Chesterbrook, Pa.) Xiaflex Collagenase clostridium histolyticum Peyronie's disease Pivotal Phase III data showed that both Xiaflex co-primary endpoints met statistical significance at 52 weeks compared to placebo, and Xiaflex was generally well tolerated 2/5/13

Mean FEV1 value for the active treatment group increased 120ml from baseline to day 42 and decreased 40ml for the placebo group

The results showed that 33.1 percent of patients in the apremilast group met that benchmark, compared to 5.3 percent in the placebo group (p < 0.0001

People in that dose group experienced influenza-like symptoms for a median of 1.9 days, compared to 3.7 days in the placebo group...Also, 93 percent of people in that dose group showed no clinical symptoms of influenza after three days of treatment, compared to 41 percent of people in the placebo group

All of the 13 studies had malignancy in the calcitonin-treated group, while seven of the placebo groups were free of malignancy

Vertex plans to conduct two 24-week studies – TRAFFIC and TRANSPORT – in CF patients, ages 12 and older, with each study including two treatment groups and a placebo group