By substituting a halogen atom (chlorine or iodine) for an oxygen, one "confers substantial lipophilicity on these new analogs, but they appear to exert their anti-viral activity only upon conversion to ddI or ddG (dideoxyguanosine)." -- David N. Leff Science Editor (c) 1997 American Health Consultants
For the latter, you wouldn't want to induce proliferation, which can have deleterious effects of cellular overgrowth." -- David N. Leff Science Editor (c) 1997 American Health Consultants
of Cambridge, Mass., and Xoma Corp.., Berkeley, Calif., are among the leaders in ricin immunotoxins for cancer therapy. -- David N. Leff Science Editor (c) 1997 American Health Consultants
5,077,201, which lists 18 claims for the use of a mutated fungal culture to produce indigo. -- David N. Leff Science Editor (c) 1997 American Health Consultants
In the pharmaceutical field, disclosures concern diagnosis and therapy of Alzheimer's disease, plasmin-inhibiting antibodies and ricin toxin chains for monoclonal-conjugation, and multifunction expression vectors. -- David N. Leff Science Editor (c) 1997 American Health Consultants
for more than 100 staffers, $207,300. -- Likewise, the team of top managers grows with company size, from a lean head count of four team players -- CEO, chief financial officer, vice president of research and development, VP of operations -- in a company with 25 or fewer employees, to double that number -- adding VPs for sales and marketing, regulatory affairs, human resources and business development -- for one with 100 or more people on staff. -- David N. Leff Science Editor (c) 1997
Pan-Bs, Krawiec explained, target and bind to a B-cell surface marker present on the tumors of more than 90 percent of all lymphoma patients. -- David N. Leff Science Editor (c) 1997 American Health Consultants
It doesn't require special machines or additional know-how because the technology will be contained in the seed." -- David N. Leff Science Editor (c) 1997 American Health Consultants
subsidiary of a large French company, Ipsen-Beaufour of Paris, which has a $600 million turnover in therapeutic drugs "If we select their peptide," said Dean, "by the mid-1990s, we can look forward to product copromotion by both our sales forces of their therapeutic and our imaging agent." -- David N. Leff Science Editor (c) 1997 American Health Consultants
She suggests that "current hiring efforts are a clear indicator of the growth orientation of this industry." -- David N. Leff Science Editor (c) 1997 American Health Consultants
His company is actively pursuing its anti-viral program, Kelley added, but "does not at present have any compounds in preclinical development." -- David N. Leff Science Editor (c) 1997 American Health Consultants
Pastan foresees the single-chain toxin conjugate as being used primarily to scavenge residual metastatic cells of many tumor types, once the main bulk of a solid tumor has been surgically removed. -- David N. Leff Science Editor (c) 1997 American Health Consultants
That's my ultimate dream," Stierle told BioWorld. -- David N. Leff Science Editor (c) 1997 American Health Consultants