Early stage and pilot Phase II data presented at the conference showed that ACH-3102 was active against both wild-type and NS5A-resistant viral variants, leading to sustained virologic response in treatment-naïve patients with genotype 1b, IL28B CC subtype, and that the drug had no clinically significant pharmacokinetic interactions with sovaprevir
By Anette Breindl | BioWorld Today | Wednesday, April 24, 2013
Although the program, HD-001, is in its early stages, Disley said the agreement can be benchmarked to other deals around first-in-class kinases...This early stage deal with Horizon, along with an agreement with a $199 million-plus deal with BIND Therapeutics Inc
By Nuala Moran | BioWorld International | Wednesday, April 24, 2013
Avalon is collaborating with London-based GSK to fund and launch up to 10 early stage life science companies in San Diego, which is Avalon's base of operations...Last week, Lichter – profiled for his ability to get early stage deals done – said Avalon has let investors capitalize on the problem for big pharma that "eventually, the available Phase II and Phase III assets that are out there, that are good, would be soaked up
By Randy Osborne | BioWorld Today | Wednesday, April 24, 2013
Jonathan MacQuitty, partner at the investment group Abingworth LLP, insisted the industry needs both big pharmas and VCs to bring early stage companies to fruition...But is early stage discovery and drug development most efficiently handled by pharmas and academic institutions, which are positioned more for late-stage development and scientific exploration, respectively
By Marie Powers | BioWorld Today | Wednesday, April 24, 2013
About $15 million from the proposed IPO would be used to bolster work in the firm's earlier-stage pipeline, including GWP43004, which is in Phase II development in Type II diabetes, and GWP42003, in Phase II for ulcerative colitis
By Jennifer Boggs | BioWorld International | Wednesday, April 24, 2013
Kymab is among a slew of early stage companies that are filling the gap left by the first generation of human antibody-producing transgenic mouse strains, which have disappeared from general view following their absorption into big pharma via acquisitions
By Cormac Sheridan | BioWorld Today | Tuesday, April 23, 2013
Although the program, HD-001, is in its early stages, Disley said the agreement can be benchmarked to other deals around first-in-class kinases...This early stage deal with Horizon, along with an agreement with a $199 million-plus deal with BIND Therapeutics Inc
By Nuala Moran | BioWorld Today | Tuesday, April 23, 2013
The situation has forced early stage biotechs to look at alternative funding sources – for example, from pharmas and disease-focused foundations...King agreed, noting that companies seeking to raise money for early stage programs need to think carefully about the commercialization and reimbursement strategies that will apply to their programs
By Marie Powers | BioWorld Today | Monday, April 22, 2013
About $15 million from the proposed IPO would be used to bolster work in the firm's earlier-stage pipeline, including GWP43004, which is in Phase II development in Type II diabetes, and GWP42003, in Phase II for ulcerative colitis
By Jennifer Boggs | BioWorld Today | Monday, April 22, 2013
It takes a special kind of person to be able to help navigate a biotechnology company from its early stages, with all its attendant hopes and dreams into the reality of a truly therapeutic product organization, which generates revenue and builds value for its shareholders...I believe our combined $80.9 million financings established a new way of thinking about funding very promising early stage companies," he added
By Peter Winter | BioWorld Today | Friday, April 19, 2013
She also has experience on the venture capital side, where she was a venture partner at BattelleVentures, sourcing deals and assisting early stage companies with strategy and business development
By Catherine Shaffer | BioWorld Today | Wednesday, April 17, 2013
Avilex Pharma ApS, of Copenhagen, Denmark, said it has received seed funding from Novo Seeds, the early stage financing arm of Novo A/S, which will be used to support the development of dimeric ligands targeting PDZ domains
BioWorld International | Wednesday, April 17, 2013
Avilex Pharma ApS, of Copenhagen, Denmark, said it has received seed funding from Novo Seeds, the early stage financing arm of Novo A/S, which will be used to support the development of dimeric ligands targeting PDZ domains
Avilex Pharma ApS, of Copenhagen, Denmark, said it has received seed funding from Novo Seeds, the early stage financing arm of Novo A/S, which will be used to support the development of dimeric ligands targeting PDZ domains
By Marie Powers | BioWorld Today | Tuesday, April 16, 2013
Afraxis, an early stage Avalon-backed concern for which Lichter serves as CEO, scored a potential $187.5 million licensing deal with Genentech, a member of the Roche Group, near the start of this year. (See BioWorld Today, Jan. 29, 2013.) Lichter "doesn't take himself too seriously
By Randy Osborne | BioWorld Today | Tuesday, April 16, 2013
Biota Pharmaceuticals, Inc., of Rockville, Md., said its board of directors has adopted a revised corporate strategy that will shift their primary focus from early stage research to clinical-stage development programs that it could independently advance into late-stage development
plans to spin out its early stage neurology drugs into Neotope Biosciences, keeping the commercial products with the parent company. (See BioWorld Today, Aug. 14, 2012.) CytRx Corp
By Brian Orelli | BioWorld Insight | Monday, April 15, 2013
Anti-arrhythmic agent budiodarone is targeting atrial fibrillation, with the oral program in Phase II and an intravenous formulation in early stage development
By Marie Powers | BioWorld Today | Monday, April 15, 2013
Early stage and pilot Phase II data presented at the conference showed that ACH-3102 was active against both wild-type and NS5A-resistant viral variants, leading to sustained virologic response in treatment-naïve patients with genotype 1b, IL28B CC subtype, and that the drug had no clinically significant pharmacokinetic interactions with sovaprevir