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BIOTECHNICA ACQUIRES SEED COMPANY
Biotechnica International Inc. (NASDAQ:BIOT) of Overland Park, Kan., announced that it has acquired NobleBear Inc., a producer and marketer of hybrid corn and soybean seed. (c) 1997 American Health Consultants. All rights reserved.BioWorld Today | Friday, January 8, 1993 -
EMISPHERE TO COLLABORATE WITH SCICLONE
Emisphere Technologies Inc. on Thursday announced a collaboration with SciClone Pharmaceuticals Inc. to work on the development of oral dosage formulations for a number of existing and future SciClone products. Emisphere could receive milestone payments as feasibility and development steps are achieved. Emisphere also said it has filed with the Securites and Exchange Commision a public offering of 1.8 million shares of common stock (NASDAQ:EMIS), of which 1.5 million are being sold by theBioWorld Today | Friday, January 8, 1993 -
CELLPRO RECEIVES PATENT NOTICES
CellPro Inc. announced Thursday that it received three end-of- the-year U.S. patent allowance notices for cell-selection technology it licenses from the Fred Hutchinson Cancer Research Center. The Bothell, Wash., company (NASDAQ:CPRO) develops proprietary, continuous-flow cell-selection systems for therapeutic, diagnostic and research applications. The Fred Hutchinson Cancer Research Center, an independent, non-profit research institution, has licensed novel methods developed there to CellProBioWorld Today | Friday, January 8, 1993 -
CELLTECH PACT FOR ANTI-CYTOKINES
Celltech Group plc announced Thursday that it has reached an agreement with a large corporate partner to develop potential therapies to block chemical messengers that mediate inflammatory disease and immune disorders. Celltech, a privately held British company, and Schering-Plough Corp., on behalf of several of its affiliated companies, said they have a collaboration and licensing agreement to develop and commercialize genetically engineered antibodies to selected cytokines. By blocking theBioWorld Today | Friday, January 8, 1993 -
IMAGING AGENT IDS CANCER SITES
A Phase II clinical trial showed that a colorectal cancer imaging agent developed by Immunomedics Inc. was able to correctly identify colorectal cancer sites. The results were published in the January 1993 issue of The Journal of Nuclear Medicine, the Morris Plains, N.J., company (NASDAQ:IMMU) announced Thursday. The prospective study of 62 patients with colorectal cancer showed that 91 percent of positive readings with the iodine- 123 labeled MAb-based product correctly identified colorectalBioWorld Today | Friday, January 8, 1993 -
TSI STOCK DOWN IN HEAVY TRADING
Shares of TSI Corp. (NASDAQ:TSIN) dropped $1.25 Thursday to close at $4.13, with more than 2 million shares changing hands. Cowen and Co.'s biotechnology group, led by analyst David Stone, downgraded its rating on the Worcester, Mass., company from "neutral/outperform" to "neutral/neutral." (The designations refer to short-term/long-term market performance estimates.) Cowen and Co. changed the rating due to its estimates for lower earnings for the company in the 1993-1995 period. In otherBioWorld Today | Friday, January 8, 1993 -
SCIOS NOVA ACQUIRES NTLP
Scios Nova Inc. announced Thursday that it has purchased the assets of Nova Technology Limited Partnership (NTLP) with the issuance of 2.5 million shares of Scios Nova common stock. NTLP was formed in 1987 by Nova Pharmaceuticals Corp., which merged with Scios Inc. last September to form Scios Nova Inc. Scios Nova will report a one-time, non-cash charge to operations of approximately $20.5 million for the fourth quarter of 1992. NTLP's assets consist primarily of research and development inBioWorld Today | Friday, January 8, 1993 -
VICAL FILES FOR IPO
Vical Inc. announced late Thursday that it has filed a registration statement with the Securities and Exchange Commission (SEC) for an initial public offering of 3 million shares of common stock at $9-11 per share. Hambrecht & Quist and Vector Securities are co-managing the offering. Vical of San Diego said it plans to use the proceedings for research and development, including preclinical and clinical studies, facilities expansion and general corporate purposes. Vical develops gene-basedBioWorld Today | Friday, January 8, 1993 -
ANALYST RECOMMENDS CENTOCOR
Centocor Inc.'s stock (NASDAQ:CNTO) rose $1.25 a share Wednesday on busy trading of about 1.8 million shares. Analyst Wole Fayemi of Hambrecht & Quist in New York upgraded his rating on the Malvern, Pa.-based company from a "speculative buy" to a "buy." Fayemi said he expects significant advances in product development over the course of 1993 and that the company's financial position continues to improve as it lowers its burn rate and revises its business strategy. (c) 1997 American HealthBioWorld Today | Thursday, January 7, 1993 -
PATCH TO MONITOR COCAINE USE
PharmChem Laboratories Inc.announced that Sudormed Inc. has filed with FDA its intention to distribute a sweat collection patch for detection of cocaine use. PharmChem (NASDAQ:PCHM) of Menlo Park, Calif., a drug testing laboratory, and Sudormed, a privately held medical device company, signed an exclusive license and supply agreement last March for the drug-detection patch. The notification was submitted to FDA following extensive clinical studies that demonstrated that cocaine use can beBioWorld Today | Thursday, January 7, 1993 -
BORON GETS SBIR GRANT
Boron Biologicals Inc. (BBI) received a $50,000 small business innovation research grant from the National Institutes of Health (NIH) to develop enzyme inhibitors that could eventually shut down virus functions. BBI research may have implications for the treatment of viral infections such as herpes and HIV, and cancer. BBI of Raleigh, N.C., was founded in 1986 to promote commercial development of a proprietary class of compounds based on boron that can have key applications in drugsBioWorld Today | Thursday, January 7, 1993 -
CREATIVE BIO UNDERWRITERS EXERCISE OPTION
Creative BioMolecules Inc. announced that its underwriting group, led by Montgomery Securities and Prudential Securities Inc., has exercised its option in connection with the company's initial public offering to purchase an additional 450,000 shares of common stock. The company, which began trading Dec. 18, raised $21 million in its 3 million-share IPO. The Hopkinton, Mass., company (NASDAQ:CBMI) is a leader in the discovery and development of proprietary protein-based products for theBioWorld Today | Thursday, January 7, 1993 -
FDA APPROVES TEST KIT FOR EXPORT
MicroProbe Corp. has received FDA permission to export a test kit for identification of microorganisms associated with periodontal disease, the most common cause of tooth loss in adults. The privately held Bothell, Wash., company plans to export its Affirm DP Microbial Identification Test System to Australia, Austria, Belgium, Denmark, Germany, Greece, Hong Kong, Norway, South Africa, Spain and Switzerland. The system, which has no FDA market clearance in the U.S., represents the first directBioWorld Today | Thursday, January 7, 1993 -
SIBIA TO CO-DEVELOP ANTI-EPILEPTIC
Sibia Inc. and the Pharmaceutical Sector of the Belgian drug and chemical company UCB announced that they have agreed to develop and co-promote an anti-epileptic drug discovered by UCB. Sibia, a private biopharmaceutical company formed by the Salk Institute for Biological Studies in 1981, will take the drug through clinical trials for treating epilepsy and obtain regulatory approval in the U.S. and Canada. The La Jolla, Calif., company and UCB will co-promote the product in the U.S. and CanadaBioWorld Today | Thursday, January 7, 1993 -
PCR IDS NEW SPECIES OF CROP PEST
Forensic geneticists are tracking down an elusive killer wanted in nine or more states, from Florida to California. In 1991, this small, sap-sucking insect, the whitefly, cost vegetable and cotton growers in California and Texas alone more than $200 million in crop damage, and the loss of some 12,000 farm jobs. "Whiteflies are not flies," said entomologist Thomas M. Perring of the University of California, Riverside. True flies, he told BioWorld, belong to the taxonomic order, Diptera; soBioWorld Today | Thursday, January 7, 1993 -
SPHINX IND FOR CHEMOTHERAPY ENHANCER
Sphinx Pharmaceuticals Corp. (NASDAQ:SPHX) announced Wednesday that it has filed an investigational new drug (IND) application with FDA to investigate Kynacyte's ability to enhance the efficacy of chemotherapeutic drugs -- including doxorubicin and cisplatin -- in treating solid tumors. The Phase I clinical trials will examine Kynacyte alone or in conjunction with doxorubicin in 20-30 cancer patients with one of several solid tumors. These patients will have either already failed previousBioWorld Today | Thursday, January 7, 1993 -
FDA APPROVES QUIDEL PREGNANCY TEST
Quidel Corp. announced Wednesday that it has received marketing clearance from FDA for its one-step, one-minute home pregnancy test, Conceive. The test detects pregnancy as early as the first day of a missed period, the San Diego company (NASDAQ:QDEL) said. It's a monoclonal antibody-based assay that detects human chorionic gonadotropic hormone (hCGH) in urine, like all the other over- the-counter pregnancy tests now available to the consumer, said Mark Francois, Quidel's manager of investorBioWorld Today | Thursday, January 7, 1993 -
ANALYSTS DEFEND MEDIMMUNE
Analyst Peter Drake of Vector Securities International Inc. on Wednesday called the sell-off of MedImmune Inc. shares "meaningfully overdone" on the heels of "unexpected research results," and issued a "buy" recommendation after the stock (NASDAQ:MEDI) tumbled more than 17 percent to $19.25 on Tuesday. The stock picked up $1.75 a share on Wednesday, closing at $21. In addition, according to MedImmune spokesman Anthony Russo, analyst Jeff Casdin of Oppenheimer & Co. has issued a long-term buyBioWorld Today | Thursday, January 7, 1993 -
ISIS PACT WITH JAPANESE DRUG COMPANY
A Japanese pharmaceutical company interested in going global has entered into an agreement with Isis Pharmaceuticals Inc. to co-develop an antisense oligonucleotide analog effective against cytomegalovirus (CMV) infections. Eisai Co. Ltd. has collaborated with Isis on CMV research since 1990. Eisai has the option to license and co-develop antisense oligonucleotides from the program that meet pre-defined criteria, upon payment of a milestone fee. Oligonucleotides are short chains of nucleotidesBioWorld Today | Thursday, January 7, 1993 -
DRUG APPROVALS: FEW AND FAR BETWEEN
Last year was lean for biotech drug approvals in the U.S. The FDA granted marketing rights to only two: Chiron/Cetus' Interleukin-2 and Genetics Institute Inc. (GI)/Baxter Healthcare's Factor VIII. FDA also approved a biotech diagnostic, Cytogen Corp.'s OncoScint, the first monoclonal antibody-based in vivo imaging agent to receive U.S. marketing approval. And 1993 might be only slightly better. "I'm not expecting a massive number of major new drug approvals in 1993," Denise Gilbert, anBioWorld Today | Wednesday, January 6, 1993
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