The proteins, company researchers said, are responsible for the natural activation of stem cells, which differentiate to form the body's various tissues, such as those that make up bone, organs and the brain
The patent, which Alexion licensed from the Biotechno- logy Research and Development Corp., covers composition of porcine embryonic stem cells for producing transgenic pigs, which are used in xenotransplantation. * Cypros Pharmaceutical Corp., of Carlsbad, Calif., received a second patent for its drug, CPC-211, for protecting brain cells from damage caused by stroke and head injury
cell expansion Stem cell factor and soluble interleukin-6 receptor used for ex vivo expansion of multipotent hematopoietic cells...Neurospheres Neural stem WO 96/15226 Calgary, Alberta cell growth Regulation of neural stem cell proliferation by the use of biological growth factors in vitro
In April, Chiron Corp., of Emeryville, Calif., entered into a long-term gene therapy collaboration that involves Chiron's use of Progenitor's nonviral vectors in developing gene therapies for cancer, cardiovascular disorders and infectious diseases. (See BioWorld Today, April 5, 1995, p. 1.) In June 1995, Progenitor signed a co-development deal with Zymogenetics Inc., a subsidiary of Bagsvaerd, Denmark-based Novo Nordisk A/S, that covers two of Progenitor's blood stem cell growth factors for
From Osteogenic Theory To Practice "Osteogenic stem cells, too, are thought to be present, and when a wound _ in our case, a fracture _ is created, it galvanizes them into action
patent applications in its xenotransplantation program relating to the composition of porcine embryonic stem cells, the use of complement inhibitors in transplantation and the genetic engineering of mammalian cells with a human complement inhibitor. * Ansan Inc., of South San Francisco, received notice of allowance of a patent for Novaheme (AH10), an analogue of butyrate, which is being developed for treating red blood cell disorders. * ArQule Inc., of Medford, Mass., was awarded patent No
SyStemix's lead technology centers around the isolation of a substantially pure hematopoietic stem cell (HSC), called CD34ThyLin, that has a number of potential applications
received an approvable letter from the FDA regarding its stem cell isolation system, which, when approved, will be the first to reach the U.S...Ceprate separates human stem cells from others cells of the bone marrow or peripheral blood
This will involve gene-targeting techniques, "probably quite similar to those being used with mouse embryonic stem cells," he suggested, adding, "With gene targeting, one can actually change existing genes, so it opens up an entirely new opportunity as far as modification of livestock is concerned...They are not like mouse embryonic stem cells," Wilmut explained
There would be a $2.5 million cash payment and the remainder in stock or cash, at the company's discretion. * Rhone-Poulenc Rorer Inc., of Collegeville, Pa., said data presented at a European transplantation conference showed its genetically engineered granulocyte colony-stimulating factor, Granocyte (lenograstim), is more potent than Neupogen, Amgen Inc.'s G-CSF, in mobilizing peripheral blood stem cells in healthy donors
Systemix Stem cell EPO 716 146 Palo Alto, Calif...marker protein Gene for stem cell marker protein, encoded protein, antibodies, purification methods