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Chance Observation Triggers Idea to Treat Polycystic Kidneys
Alessandra Boletta, associate scientist at the Dulbecco Telethon Institute and head of the research unit at the San Raffaele Scientific Institute in Milan, Italy, told BioWorld International: "We have found that the cells affected by this disease have a defective capacity to use energy and specifically are unable to use sugar to generate energy in the most common wayBy Sharon Kingman | BioWorld International | Wednesday, April 3, 2013 -
Themis Plans Trials for Dengue and Chikungunya Vaccines
The inventive step was to create a vector out of it," Themis CEO and co-founder Erich Tauber told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, April 3, 2013 -
Synthon to Debut New Focus with HER2-ADC Data at AACR
Jacques Lemmens, CEO of Synthon, told BioWorld International that ADCs "represent the future of antibody treatments for cancerBy Nuala Moran | BioWorld International | Wednesday, April 3, 2013 -
As Aastrom Falters, ReNeuron Advances Its CLI Cell Therapy
We're hoping to get that trial completed within 18 months," ReNeuron CEO Michael Hunt told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, April 3, 2013 -
ChronTech's Stock Plummets on HCV Vaccine Phase II Miss
plc. (See BioWorld International, Aug. 3, 2011.) Lynch, a former chairman and CEO of Amarin, is still in situ, but several other board members parted company with ChronTech last month, including William Hall, a virologist based at University College DublinBy Cormac Sheridan | BioWorld Today | Wednesday, April 3, 2013 -
ChronTech's Stock Plummets on HCV Vaccine Phase II Miss
plc. (See BioWorld International, Aug. 3, 2011.) Lynch, a former chairman and CEO of Amarin, is still in situ, but several other board members parted company with ChronTech last month, including William Hall, a virologist based at University College DublinBy Cormac Sheridan | BioWorld International | Wednesday, April 3, 2013 -
Clavis Faces Merger, Shutdown in Wake of Elacytarabine Miss
Olav Hellebo, CEO of Oslo, Norway-based Clavis, told BioWorld International it was the end for the technology...The fall was a smaller hit in relative terms than the news of the Phase II failure of CO-101 on Nov. 12, 2012, when Clavis' share price dropped from NOK66 to NOK8. (See BioWorld International, Nov. 14, 2012.)By Nuala Moran | BioWorld International | Wednesday, April 3, 2013 -
Biotech Mergers And Acquisitions: Sept. 1, 2012 - March 28, 2013#
For stock-based deals that have been completed, the final value was calculated based on the closing price before the merger's completion was announced. ** Denotes the date the item ran in BioWorld International. @ Conversions of non-U.SBioWorld Insight | Monday, April 1, 2013 -
Aastrom Terminates CLI Trial; Restructures, Shifts to DCM
Late last year, the Cell Therapy Catapult Center, a UK-based incubator for the cell therapy sector, determined that there is limited investment in the field from commercial backers, with big pharma observing and waiting, while SMEs (small and medium-sized enterprises) that are active lack the finance and breadth of resources needed to advance rapidly. (See BioWorld International, Dec. 12, 2012.) The center cited a lack of understanding within the pharma industry of what types of therapies areBy Catherine Shaffer | BioWorld Today | Thursday, March 28, 2013 -
SARcode Investors Reap 120% ROI in Sale to Shire
It's a nice benchmark, if you will, for a first-in-class drug for dry eye," Garheng Kong, general partner at Menlo Park, Calif.-based Sofinnova and SARcode board member, told BioWorld International...Jessica Mann, spokeswoman for Dublin, Ireland-based Shire, told BioWorld International the company was attracted to the asset because of its product differentiation potential and because it targets an area with significant unmet needBio Perspectives | Wednesday, March 27, 2013 -
SEEK's $38M to Back Spin-off; Keeps Vaccine, Antiviral Focus
has been used in other drugs, but never combined with ibuprofen before," Stoloff told BioWorld InternationalBioWorld International | Wednesday, March 27, 2013 -
SARcode Investors Reap 120% ROI in Sale to Shire
It's a nice benchmark, if you will, for a first-in-class drug for dry eye," Garheng Kong, general partner at Menlo Park, Calif.-based Sofinnova and SARcode board member, told BioWorld International...Jessica Mann, spokeswoman for Dublin, Ireland-based Shire, told BioWorld International the company was attracted to the asset because of its product differentiation potential and because it targets an area with significant unmet needBy Cormac Sheridan | BioWorld International | Wednesday, March 27, 2013 -
Immune Modulation Could Speed Bone Fracture Healing
Hans-Dieter Volk, head of the Berlin-Brandenburg Center for Regenerative Therapies (BCRT) and director of the Institute for Medical Immunology in Berlin, told BioWorld International: "Our work opens the door to two developmentsBy Sharon Kingman | BioWorld International | Wednesday, March 27, 2013 -
Santhera Withdraws Raxone MAA, Plans Resubmission
It's a number that would be of interest to the CHMP," Santhera CEO Thomas Meier told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, March 27, 2013 -
GW Pharma Files for $50M IPO with Sativex in Phase III
investors," Justin Gover, CEO told BioWorld InternationalBy Nuala Moran | BioWorld International | Wednesday, March 20, 2013 -
ThromboGenics Banks $59M Milestone on EU Approval
Ninety-five percent of them get acquired – that's just a given," Jan De Kerpel, analyst at KBC Securities in Brussels, Belgium, told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, March 20, 2013 -
Anticancer Drugs May Hold Key to Parasite Treatment
Matthew Berriman, a co-author of the paper, and group leader for parasite genomics at the Wellcome Trust Sanger Institute, told BioWorld International: "This work lays everything out for the entire tapeworm research community to mine, and provides a shortcut to drug discoveryBy Sharon Kingman | BioWorld International | Wednesday, March 20, 2013 -
Safinamide Hits Endpoints in Two Parkinson's Phase III Trials
Ravi Anand, chief medical officer at Milan, Italy-based Newron told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, March 20, 2013 -
Helmedix Lands Seed Funding to Back Helminth Peptide R&D
By the end, we hope to have a lead candidate, know the mode of action and be ready to consider clinical development," Thompson told BioWorld InternationalBy Nuala Moran | BioWorld International | Wednesday, March 20, 2013 -
Grants, Contracts And Awards To Biotech Companies: Oct. 1, 2012 - March 14, 2013
Company (Location) Funding Institution Amount (US$M) Type Details Date OCTOBER Addex Therapeutics SA (Geneva) Swiss Commission for Technology and Innovation CHF0.7 ($0.748) Grant For development of allosteric modulators for neurodegenerative and psychiatric diseases 10/3/12 Advanced Cancer Therapeutics Inc. (Louisville, Ky.) National Cancer Institute $0.158 Phase I SBIR grant To support the development of an inhibitor of glycolysis targeting 6-phosphofructo-2 kinase/fructose 2,6-biphosphatase 3BioWorld Insight | Monday, March 18, 2013
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