While there are many interrelated causes, two of the main ones are a failure to make long-term investments in drug development pipelines and a hostile regulatory climate toward animal, especially rodent, research...Coming on top of the closure two years ago of Pfizer's R&D center in Sandwich, UK, where 2,400 people were employed, the announcement of at least 700 job losses at AstraZeneca "risks further reducing the UK's collective capability" in drug development, Downs said

The academic PI sits on the drug development team, so instead of hiring a key opinion leader to come in once a year and tell us whether we're doing a good job, we usually have the expert in that pathway, in that biology, in that target, someone who's worked on it for decades, actually sitting on our drug development team," Lindberg said

This is certainly good news for the pharmaceutical industry and biotechs that are active in AD drug development

This is certainly good news for the pharmaceutical industry and biotechs that are active in AD drug development...Biomarker Development Following the Science The FDA makes clear, however, that there's no getting around the need for biomarker development to go hand in hand with drug development in early AD

Sunshine Biopharma Inc., of Montreal, said it started negotiations with several contract manufacturing organizations for the GMP manufacturing of 1 kg of Adva-27a, its drug in development for treating breast cancer that has become resistant to existing therapeutics

The FDA published a notice in the Federal Register about the public workshop called "Drug Development for Chronic Fatigue Syndrome...It's the first such workshop held as part of the Patient-Focused Drug Development initiative, mandated in the authorization of the Prescription Drug User Fee Act, and a prime topic, given the uproar over the agency's refusal to approve Ampligen (rintatolimod) after a negative advisory panel meeting in December. (See BioWorld Today, Dec. 21, 2012.) Ampligen was the

Changes in the scientific understanding of how to modulate SIRT1 could affect drug development timetables, according to an analysis of the paper scheduled for the March 18 issue of BioWorld Insight

Founded in 2007, Auven is structured as a private equity fund that also operates as a drug development company

The Reproductive Health Drugs and the Drug Safety and Risk Management advisory committees voted 20-1 that sponsors of calcitonin drugs in development should be required to submit fracture efficacy data for approval

The first signs surfaced in about 2007 that maybe China and India would not soon become the drug-development giants that the U.S

Zhangjiang Biotech Pharmaceutical Base will be able to consult with HUYA's experts in drug development and commercialization, while HUYA will have the first opportunity to evaluate certain R&D projects conducted at the base

Repurposing approved drugs – many of which already are being used for symptom relief – to give them official labels for chronic fatigue syndrome (CFS) will be one topic at an FDA-sponsored workshop next month on drug development for CFS and myalgic encephalomyelitis (ME

The Reproductive Health Drugs and the Drug Safety and Risk Management advisory committees voted 20-1 that sponsors of calcitonin drugs in development should be required to submit fracture efficacy data for approval

QIDP designation is under the GAIN Act included in the 2012-passed FDASIA legislation and is designed to provide drug development with incentives for creating new antibacterial and antifungal drugs

Deals 4SC AG signed a preclinical drug development deal in inflammatory skin disease with Leo Pharma A/S. Ablynx NV and Spirogen Ltd

I have to confess, it is very difficult to break from the classic paradigm of single-target drug development." – Winston Ko, chairman and CEO of Genervon Biopharmaceuticals Inc

The problem is that the traditional drug development approach of designing single-target drugs for CNS diseases simply hasn't worked, said Winston Ko, chairman and CEO of Genervon Biopharmaceuticals Inc., a firm he founded in 2002 to develop MNTF, a family of nine master regulators of the CNS...I have to confess, it is very difficult to break from the classic paradigm of single-target drug development," he said

Although three of the seven centers are focused on life sciences – and a fourth has a significant life sciences strand – none will perform discovery research leading to drug development, although Science Foundation Ireland (SFI) continues to fund basic life sciences research through its principal investigators program

4SC AG could earn up to €96 million (US$125 million) in option and milestone payments arising out of a preclinical drug development deal in inflammatory skin disease with Leo Pharma A/S, as well as double-digit royalties on eventual product sales