More generally, similar approaches have the potential to allow researchers to probe the genes and proteins responsible for a whole range of phenotypes in both microorganisms and cell cultures, including the causes of drug resistance in tumor cell lines

Moreover, the metabolite caused the release of pro-inflammatory cytokines in cell culture, resulting in pain when it was injected into animals

They then grew such enriched populations in cell culture and tested whether treatment with the chemotherapies doxorubicin or cisplatin affected their growth...It did – by speeding it up: In cell culture, treated cells also formed more and larger colonies than untreated ones

In cancer cell culture, Ablitech has demonstrated the ability to release the prodrug moieties placed on DNA and RNA strands through a basic mechanism that doesn't require special enzymes or processes

Using three-dimensional cell cultures, the authors found that mutant p53 led cells to become unable to form so-called acinar structures, which keep breast cells organized – among other things, they help to prevent out-of-control cell division – under normal circumstances...In cell culture, the cells kept dividing for several weeks, and "when transplanted into mice, the programmed cells gave rise to ectopic fat pads with the morphological and functional characteristics of white or brown adipose

In both cell culture and in vivo experiments, Mukhopadhyay and Linstedt showed the binding rerouted shiga toxin into the lysosome

Id1 high cells form so-called tumor spheres in cell culture, which is one hallmark of a cancer stem cell

Id1 high cells form so-called tumor spheres in cell culture, which is one hallmark of a cancer stem cell

Using cell culture studies, the authors showed that expression of Niemann-Pick C1–like 1 or NPC1L1 cholesterol uptake receptor is necessary for hepatitis C to infect liver cells...Both RNA silencing and antibodies to the receptor blocked infection of cells with hepatitis C in cell culture

The Georgia team is currently testing in which types of cells – including human cell culture lines – the system could be used to silence RNA

Moore and her team demonstrated that in cell culture, netrin-expressing macrophages did not migrate toward a source of CCL2

The new data address concerns about tumors from a study of lorcaserin carcinogenicity in rats, as well as cell culture studies on serotonin subtype 2 receptor activity

The retinal pigment epithelium usually does not have adult stem cells, but the authors were able to generate such stem cells from mature cells in cell culture

To keep most adult cells going in cell culture requires changing their gene expression

But in cell culture studies, the authors found the antibody's actions of FGFR1 were "sufficient" to replicate the effects of recombinant FGF21

and cytokine reagents, diagnostics and growth factor supplements for the cell culture and biotech manufacturing industries

8,044,201, titled "Stem Cell Cultures," which claims Thiazovivin, a small-molecule Rho-associated kinase inhibitor, as well as compositions and cell culture media comprising Thiazovivin

BPTC, of Woburn, Mass., just completed a survey of commercial mammalian cell culture facilities worldwide

BPTC, of Woburn, Mass., just completed a survey of commercial mammalian cell culture facilities worldwide