However, those investments can involve big pharma spinouts – a feature of European drug development – as well as classical start-ups and newly formed companies emerging from restructuring events...Papiernik characterized the current realignment in drug development as a division of labor

Gentium SpA, of Villa Guardia, Italy, inked an agreement with the National University Corporation Hamamatsu University School of Medicine (HUSM), Fukushima Medical University and LINK Healthcare to provide drug and technical support to a clinical trial of defibrotide, a drug in development for veno-occlusive disease, in healthy adults

However, those investments can involve big pharma spinouts – a feature of European drug development – as well as classical start-ups and newly formed companies emerging from restructuring events...Papiernik characterized the current realignment in drug development as a division of labor

Gentium SpA., of Villa Guardia, Italy, inked an agreement with the National University Corporation Hamamatsu University School of Medicine (HUSM), Fukushima Medical University and LINK Healthcare to provide drug and technical support to a clinical trial of defibrotide, a drug in development for veno-occlusive disease, in healthy adults

Schnee said he believes the timing of the Phase III trial of Ularitide could not be better, coming as another front-running drug in development for the treatment of acute heart failure, Novartis AG's serelaxin (RLX030), delivered mixed Phase III data

Schnee said he believes the timing of the Phase III trial of Ularitide could not be better, coming as another front-running drug in development for the treatment of acute heart failure, Novartis AG's serelaxin (RLX030), delivered mixed Phase III data

But drug development expertise is thin on the ground, an issue that is exacerbated by the absence of any native big pharma firms and by the absence of other forms of assistance

is proving that, in drug development, it pays to stay flexible

To facilitate this, the company is establishing Chorus Canada in Montreal – an autonomous unit of Lilly, a global early phase drug development network...Using this approach, Chorus has been able to reach decisions on drug development about 12 months earlier and at about half the cost of the current industry model. (See BioWorld Today, Feb. 1, 2010.) These initiatives are beginning to have an impact

The government gave us special money in the aftermath of the AstraZeneca layoffs, to put together, in an academic setting, a drug development toolbox," Mathias Uhlen, managing director of SciLifeLab Stockholm, told BioWorld International...Those highly experienced scientists are developing service-based businesses based around various aspects of drug development research, while on gardening leave from AstraZeneca

Lorus Therapeutics Inc., of Toronto, partnered with Cancer Research UK's Drug Development Office (DDO) and the charity's commercial arm, Cancer Research Technology, to move a cancer treatment into clinical testing

the investment is $295M, with Hisun holding a 51% share and Pfizer holding 49% 9/14/12 Sanofi SA (Paris) Global Alliance for TB Drug Development ND Research and collaboration deal to accelerate the discovery and development of compounds against tuberculosis The two parties will work together to further optimize and develop several compounds in Sanofi's library that have demonstrated activity against Mycobacterium tuberculosis 9/21/12 SFJ Pharmaceuticals Group (San Francisco) Pfizer Inc. (New

The idea for the database predated TransCelerate BioPharma Inc., the industry's new collaborative effort to accelerate drug development, but that will serve now as a foundation for the initiative

drug development experience with ICR's expertise in blood cancer biology 9/7/12 BioLineRx Ltd. (Jerusalem) Biokine Therapeutics Ltd. (Rehovot, Israel) $0.25 Exclusive, worldwide license agreement for the development and commercialization of BL-8040, a selective antagonist of chemokine receptor CXCR4 There is no up-front payment, but BioLineRx will pay a monthly development fee ranging from $50,000 to $100,000, as well as a $250,000 milestone payment, plus royalties on a sliding scale for any

Citing oncology, immunology, psoriasis, Crohn's disease and neurology as the most attractive therapeutic areas for drug development and partnering, Conover advised biotechs to structure deals that provide most of the economics at the outset rather than relying on follow-up agreements

Also, at a time when drug development costs are skyrocketing, dermatology offers a drug development pathway that's "probably a little more predictable and a little shorter compared to something like oncology or diabetes," he noted

RXi Pharmaceuticals Corp., of Westborough, Mass., reported pharmacokinetics from a Phase I study of RXI-109, an sd-rxRNA drug in development for dermal scarring after surgery or trauma and hypertrophic scars and keloids

Earlier this year, Janssen and nine other companies joined forces to create TransCelerate BioPharma Inc., an initiative aimed at identifying and overcoming common drug development challenges to improve the quality of clinical studies. (See BioWorld Today, Sept. 26, 2012

Egenix Inc., of Millbrook, N.Y., appointed Bob Bishop, Jerry Shipps, Alan Cooper and Arshad Siddiqui to its drug development team, and added Rainer Fuchs to its board