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Biotech-Biotech Collaborations: Modified And Terminated Agreements: Nov. 1 - Dec. 20, 2012
under the terms, TA Sciences will pay Geron a nonrefundable, up-front termination and assignment fee of $2.5 million, and Asia Biotech and TA Sciences will remove all references to Geron from all online and printed marketing materials 12/11/12 Notes: The date indicated refers to the BioWorld Today issue in which the news item can be found. ** Denotes the date the item ran in BioWorld InternationalBioWorld Insight | Wednesday, December 26, 2012 -
Clinic Roundup
BioAlliance Pharma SA, of Paris, said the European Independent Board of Experts held its first meeting on the ReLive Phase III trial evaluating the efficacy of Livatag (doxorubicin Transdrug) in primary liver cancer and recommended continuing the global, multicenter, randomized study without modification. (See BioWorld International, June 29, 2011BioWorld Today | Friday, December 21, 2012 -
Targeting RORgamma, Phenex, J&J Ink $135M Collaboration
What we have counted is all clinical milestones up to and including approval," Claus Kremoser, CEO of Ludwigshafen, Germany-based Phenex told BioWorld InternationalBio Perspectives | Wednesday, December 19, 2012 -
Dutalys Gets First Taker for Bispecific Antibody Platform
It will cover half of the budget for next year," Thomas von Rüden, an angel investor who is acting as a business advisor to the company, told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, December 19, 2012 -
Epithelial Cells Eat Neighbors, Influence Lung Inflammation
In the body, almost any cell can eat other cells," Kodi Ravichandran told BioWorld InternationalBy Anette Breindl | BioWorld International | Wednesday, December 19, 2012 -
MorphoSys Gets $70M for Abd Serotec Unit; Focusing on R&D
The Abd Serotec unit comprises three main components: the company's in-house research antibody business, Antibodies by Design, along with Biogenesis Ltd., of Poole, UK, which MorphoSys acquired in 2005 for £5.25 million (US$8.5 million), and Oxford, UK-based Serotec Ltd., which it acquired for €29.3 million in cash and shares in 2006. (See BioWorld International, Jan. 16, 2006.) Revenues for the business peaked at €20.2 million in 2010 but dropped to €19.3 million in 2011 and looked likely toBy Cormac Sheridan | BioWorld International | Wednesday, December 19, 2012 -
CHMP Backs Biotie Therapies' Selincro in Alcohol Dependence
The 10-year market exclusivity starts ticking from the formal commission decision," Biotie CEO Timo Veromaa told BioWorld International...The company disclosed last week that its Parkinson's disease drug tozadenant (SYN115), which it is co-developing with UCB SA, of Brussels, Belgium, hit the primary endpoint of a Phase IIb trial. (See BioWorld International, Dec. 12, 2012.)By Cormac Sheridan | BioWorld International | Wednesday, December 19, 2012 -
Evotec Finds New Partner for NMDA Drugs in Janssen Deal
We've worked hard to reposition and find another partner, and this is a validation of that effort," Polywka told BioWorld International...Roche had options to buy back the compounds, but decided against doing so in May 2011, after Evotec terminated a Phase II proof-of-concept trial of lead product EVT 101 in treatment-resistant depression because of difficulties in recruiting patients. (See BioWorld International, May 25, 2011.) That decision cost Evotec $65 million due if Roche had exercised theBy Nuala Moran | BioWorld International | Wednesday, December 19, 2012 -
Targeting RORgamma, Phenex, J&J Ink $135M Collaboration
What we have counted is all clinical milestones up to and including approval," Claus Kremoser, CEO of Ludwigshafen, Germany-based Phenex told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, December 19, 2012 -
MorphoSys Gets $70M for Abd Serotec Unit; Focusing on R&D
The Abd Serotec unit comprises three main components: the company's in-house research antibody business, Antibodies by Design, along with Biogenesis Ltd., of Poole, UK, which MorphoSys acquired in 2005 for £5.25 million (US$8.5 million), and Oxford, UK-based Serotec Ltd., which it acquired for €29.3 million in cash and shares in 2006. (See BioWorld International, Jan. 16, 2006.) Revenues for the business peaked at €20.2 million in 2010 but dropped to €19.3 million in 2011 and looked likely toBy Cormac Sheridan | BioWorld Today | Tuesday, December 18, 2012 -
Evotec Finds New Partner for NMDA Drugs in Janssen Deal
Roche had options to buy back the compounds, but decided against doing so in May 2011, after Evotec terminated a Phase II proof-of-concept trial of lead product EVT 101 in treatment-resistant depression because of difficulties in recruiting patients. (See BioWorld International, May 25, 2011.) That decision cost Evotec $65 million due if Roche had exercised the right to take EVT 101 back in-house, plus a further $225 million in development and commercial milestones if the product had made it toBy Nuala Moran | BioWorld Today | Tuesday, December 18, 2012 -
CHMP Backs Biotie Therapies' Selincro in Alcohol Dependence
The company disclosed last Tuesday that its Parkinson's disease drug tozadenant (SYN115), which it is co-developing with UCB SA, of Brussels, Belgium, hit the primary endpoint of a Phase IIb trial. (See BioWorld International, Dec. 12, 2012.)By Cormac Sheridan | BioWorld Today | Monday, December 17, 2012 -
Evotec Finds New Partner for NMDA Drugs in Janssen Deal
Roche had options to buy back the compounds, but decided against doing so in May 2011, after Evotec terminated a Phase II proof-of-concept trial of lead product EVT 101 in treatment-resistant depression because of difficulties in recruiting patients. (See BioWorld International, May 25, 2011.) That decision cost Evotec $65 million due if Roche had exercised the right to take EVT 101 back in-house, plus a further $225 million in development and commercial milestones if the product had made it toBy Nuala Moran | BioWorld Today | Monday, December 17, 2012 -
Sofinnova Closes $312M 7th Fund; Bets on Life Sciences
Life sciences is what has provided most of the returns at Sofinnova over a long period of time, across all of the funds," managing partner, Antoine Papiernik, told BioWorld InternationalBio Perspectives | Wednesday, December 12, 2012 -
Clavis Shares Boosted on Elacytarabine Data in AML
43 percent is a good signal," Olav Hellebø, CEO of Oslo, Norway-based Clavis told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, December 12, 2012 -
Study Confirms Zytiga's Benefit in Earlier-Stage Prostate Cancer
Andy Burrows, director of investor relations at BTG, told BioWorld International that analysts are predicting "at least a $500 million increase in sales" as a result of the label extensions in the U.SBy Nuala Moran | BioWorld International | Wednesday, December 12, 2012 -
Whole-Genome Sequencing Gets $161M Boost in Britain
The tax breaks on offer would attract money from a swath of midrange earners at a time when low interest rates mean returns on traditional savings and investment instruments have hit rock bottom, the BIA said. (See BioWorld International, Sept. 5, 2012.) Stephen Whitehead, chief executive of the Association of the British Pharmaceutical Industry, echoed Bates' assessment, saying a lot more needs to be done to maintain the UK's standing as an attractive place for pharma companies to operateBy Nuala Moran | BioWorld International | Wednesday, December 12, 2012 -
Biotie Edges Up on Tozadenant Phase IIb Data in Parkinson's
The decrease associated with tozadenant was "clinically relevant and statistically highly significant," Biotie CEO Timo Veromaa told BioWorld InternationalBioWorld International | Wednesday, December 12, 2012 -
Sofinnova Closes $312M 7th Fund; Bets on Life Sciences
Life sciences is what has provided most of the returns at Sofinnova over a long period of time, across all of the funds," managing partner, Antoine Papiernik, told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, December 12, 2012 -
Metabolic Network Analysis Yields Heart Disease Genes
Panos Deloukas, senior group leader in the department of human genetics at the Wellcome Trust Sanger Institute, told BioWorld International: "We have found new genetic risk factors for CADBy Sharon Kingman | BioWorld International | Wednesday, December 5, 2012
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