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CHMP Backs Biotie Therapies' Selincro in Alcohol Dependence
The company disclosed last Tuesday that its Parkinson's disease drug tozadenant (SYN115), which it is co-developing with UCB SA, of Brussels, Belgium, hit the primary endpoint of a Phase IIb trial. (See BioWorld International, Dec. 12, 2012.)By Cormac Sheridan | BioWorld Today | Monday, December 17, 2012 -
Evotec Finds New Partner for NMDA Drugs in Janssen Deal
Roche had options to buy back the compounds, but decided against doing so in May 2011, after Evotec terminated a Phase II proof-of-concept trial of lead product EVT 101 in treatment-resistant depression because of difficulties in recruiting patients. (See BioWorld International, May 25, 2011.) That decision cost Evotec $65 million due if Roche had exercised the right to take EVT 101 back in-house, plus a further $225 million in development and commercial milestones if the product had made it toBy Nuala Moran | BioWorld Today | Monday, December 17, 2012 -
Sofinnova Closes $312M 7th Fund; Bets on Life Sciences
Life sciences is what has provided most of the returns at Sofinnova over a long period of time, across all of the funds," managing partner, Antoine Papiernik, told BioWorld InternationalBio Perspectives | Wednesday, December 12, 2012 -
Clavis Shares Boosted on Elacytarabine Data in AML
43 percent is a good signal," Olav Hellebø, CEO of Oslo, Norway-based Clavis told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, December 12, 2012 -
Study Confirms Zytiga's Benefit in Earlier-Stage Prostate Cancer
Andy Burrows, director of investor relations at BTG, told BioWorld International that analysts are predicting "at least a $500 million increase in sales" as a result of the label extensions in the U.SBy Nuala Moran | BioWorld International | Wednesday, December 12, 2012 -
Whole-Genome Sequencing Gets $161M Boost in Britain
The tax breaks on offer would attract money from a swath of midrange earners at a time when low interest rates mean returns on traditional savings and investment instruments have hit rock bottom, the BIA said. (See BioWorld International, Sept. 5, 2012.) Stephen Whitehead, chief executive of the Association of the British Pharmaceutical Industry, echoed Bates' assessment, saying a lot more needs to be done to maintain the UK's standing as an attractive place for pharma companies to operateBy Nuala Moran | BioWorld International | Wednesday, December 12, 2012 -
Biotie Edges Up on Tozadenant Phase IIb Data in Parkinson's
The decrease associated with tozadenant was "clinically relevant and statistically highly significant," Biotie CEO Timo Veromaa told BioWorld InternationalBioWorld International | Wednesday, December 12, 2012 -
Sofinnova Closes $312M 7th Fund; Bets on Life Sciences
Life sciences is what has provided most of the returns at Sofinnova over a long period of time, across all of the funds," managing partner, Antoine Papiernik, told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, December 12, 2012 -
Metabolic Network Analysis Yields Heart Disease Genes
Panos Deloukas, senior group leader in the department of human genetics at the Wellcome Trust Sanger Institute, told BioWorld International: "We have found new genetic risk factors for CADBy Sharon Kingman | BioWorld International | Wednesday, December 5, 2012 -
German Court Opens Door on Embryonic Stem Cell Patents
That resulted in last year's ruling, which for some sounded the death knell for human ESC research in Europe. (See BioWorld Today, Oct. 19, 2011.) "People were really jumping to all sorts of conclusions after the CJEU decision was given," Nick Bassil, patent attorney at Kilburn & Strode in London, told BioWorld International...They have effectively acknowledged that there are technologies that you can use to get embryonic stem cells that don't result in the destruction of an embryo," Paul ChapmanBy Cormac Sheridan | BioWorld International | Wednesday, December 5, 2012 -
Orphan Europe, Erytech Ink Deal for New Asparaginase
We produce the final batch in our own GMP facility," Erytech CEO Pierre-Olivier Goineau told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, December 5, 2012 -
Approvals Up, Revenues Down, but R&D Productivity on Mend
Companies are facing up to two dimensions of momentum," Julian Remnant, R&D advisory partner at the consultant firm Deloitte, and co-author of the study, told BioWorld InternationalBy Nuala Moran | BioWorld International | Wednesday, December 5, 2012 -
Cardiorentis' Heart Failure Trial Backed by $131M Investment
They have put in €100 million to buy the asset and complete the Phase III trial of Ularitide," he told BioWorld InternationalBy Nuala Moran | BioWorld International | Wednesday, December 5, 2012 -
Asceneuron Latest Ascension From Merck's Geneva Ashes
We don't have them prioritized," Armstrong told BioWorld International...We've worked to get a portfolio of programs together that target very distinct mechanisms of action in Alzheimer's disease," Bulthuis told BioWorld InternationalBy Marie Powers | BioWorld International | Wednesday, December 5, 2012 -
Genovax Cancer Vaccine Deal a First for Eporgen's Portfolio
We believe it can be much broader than that," Eporgen's president, Konstantinos Efthymiopoulos, told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, December 5, 2012 -
Venture Capital And Other Investments In Private Biotechnology Companies: November 2012
Canterbury, UK $27 Ziarco received $27M through a Series A round led by Biotechnology Venture Fund LP and including Pfizer Venture Investments 11/5/12 Notes: Currency conversions are based on exchange rates at the time of the deal. ** Denotes the date the item ran in BioWorld InternationalBioWorld Insight | Monday, December 3, 2012 -
NeuroVive Entering Chinese Market with Sihuan Alliance
The up-front is not as important as the 10 percent royalty rate, which is a significant achievement for us," Mikael Bronnegard, CEO of NeuroVive, told BioWorld InternationalBy Nuala Moran | BioWorld International | Wednesday, November 28, 2012 -
Sweden Bolstering Research Despite an Uncertain Climate
It is a major beneficiary of a recent increase in Sweden's science budget. (See BioWorld International, Sep. 12, 2012.) At SEK40 million (US$6 million) per year for the next four years, SciLifeLab's funding for drug development is, Uhlen said, "a drop in the ocean" compared with big pharma's R&D spend, although the available cash should leverage additional external funding...It's a wonderful opportunity," CEO Anders Dahlstrand told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, November 28, 2012 -
MorphoSys Backs Dutch Firm Lanthio in $6M Series A Round
We've trained Lactococcus lactis bacteria to introduce lanthionine rings into any peptide that we're interested in," CEO Bart Wuurman told BioWorld International...We haven't allocated a fixed amount that we want to invest," MorphoSys' chief financial officer, Jens Holstein, told BioWorld InternationalBy Cormac Sheridan | BioWorld International | Wednesday, November 28, 2012 -
Apitope Plans 2013 Financing to Advance Autoimmune Drugs
We want funds to get the two products to the end of Phase I, so a reasonable amount is needed for that," Keith Martin, CEO, told BioWorld InternationalBy Nuala Moran | BioWorld International | Wednesday, November 28, 2012
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