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Sperm-Killing Weed Killers?

2 Taste Genes Turn Out to Be Critical for Male Fertility

By Anette Breindl
Science Editor

Tuesday, July 2, 2013
Two proteins involved in sensing taste also play a very different role, researchers have discovered. In the taste system, the receptors TAS1R3 and GNAT3, part of the G protein that transduces TAS1R3's signaling, cooperate on sweet and umami tastes. But in the testicles, they are critical for male fertility. Genetically engineered mice lacking functional versions of both proteins were unable to produce healthy sperm and, consequently, offspring.

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